blaoxa464

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beta-lactamase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to blaoxa464

AMR Rules

Browse AMR rules for blaoxa464

Validation StatusCandidate

Overview

Mechanism: beta-lactam resistance
Validation Method: whole genome sequencing
Drug Classes: beta lactams, penicillin, ampicillin
Organisms: Arcobacter butzleri
Geographic Location: Ghana, Shenzhen, China
Papers: 2
Databases: Reslit

Papers2

Genetic characteristics, antimicrobial resistance, and prevalence of Arcobacter spp. isolated from various sources in Shenzhen, China.

PMID 36532418 · 2022

The study identified several AMR genes in Arcobacter spp., including beta-lactamase genes (blaOXA464, blaOXA491), tetracycline resistance genes (tet(L), tet(H), tet(M)), a macrolide resistance gene (ere(A)), and aminoglycoside resistance genes (APH(3')-IIIa, ant(6)-Ia, SAT-4). Additionally, a mutation in the gyrA gene (C254T) was found to confer fluoroquinolone resistance.

Gene Information

Gene Name: blaoxa464
Allele: blaOXA464
Encodes: beta-lactamase
Source Database: Reslit
Confers Resistance To: beta lactams
Organisms Tested In: • Arcobacter butzleri
Geographic Location: Shenzhen, China
Validation Method: whole genome sequencing
Sequence Accession: SAMN30871879|SAMN30871970

Molecular characterization of Arcobacter butzleri isolates from poultry in rural Ghana.

PMID 36761899 · 2023

The study identified several antimicrobial resistance genes in Arcobacter butzleri isolates from poultry in Ghana, including blaOXA-464, tetM, ermB, and others, highlighting the presence of multidrug-resistant strains and the potential for horizontal and vertical transmission of resistance genes.