Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
carbapenemase
Overview
Evaluation of a Commercial Multiplex PCR for Rapid Detection of Multi Drug Resistant Gram Negative Infections.
The study evaluates a commercial multiplex PCR (MT PCR) for detecting resistance genes in multi-drug resistant gram-negative organisms. It identifies several resistance genes, including blaIMP11, blaOXA48, TEM, and CTX-M-1, demonstrating the PCR's sensitivity and specificity for detecting these genes.
Bla-OXA48 gene microorganisms outbreak, in a tertiary Children's Hospital, Over 3 years (2012-2014): Case Report.
The study describes an outbreak of Klebsiella pneumoniae OXA48 (KOXA48) in a tertiary children's hospital from 2012 to 2014, highlighting the importance of studying the susceptibility of the epidemic strain to antiseptics and surface disinfectants. The KOXA48 strain was found to be resistant to carbapenems and showed limited susceptibility to the surface disinfectant Sanitbio, leading to the reinforcement of disinfection protocols.
Susceptibility rates of clinically important bacteria collected from intensive care units against colistin, carbapenems, and other comparative agents: results from Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART).
The study identified bla KPC and bla OXA48 carbapenemase genes in carbapenem-insusceptible Klebsiella pneumoniae isolates and mcr-1 colistin resistance gene in Enterobacter cloacae isolates.
First Study of Antimicrobial Activity of Ceftazidime-Avibactam and Ceftolozane-Tazobactam Against Pseudomonas aeruginosa Isolated from Patients with Urinary Tract Infection in Tehran, Iran.
The study identified several beta-lactamase and carbapenemase genes, including bla OXA10, bla VIM, bla OXA48, bla OXA2, bla CTX-M, bla PER, and bla NDM, which contribute to resistance against ceftazidime-avibactam and ceftolozane-tazobactam in Pseudomonas aeruginosa isolates from Iran.
Antibiotic resistance and virulence genes profiling of Vibrio cholerae and Vibrio mimicus isolates from some seafood collected at the aquatic environment and wet markets in Eastern Cape Province, South Africa.
The study identified various antibiotic resistance genes and virulence genes in Vibrio cholerae and Vibrio mimicus isolates from seafood samples in South Africa, highlighting the presence of resistance to multiple antibiotics including polymyxin B, ampicillin, and fluoroquinolones.
Biofilm-producing and carbapenems-resistant Escherichia coli nosocomial uropathogens: a cross-sectional study.
The study identified blaOXA48 and blaVIM genes as contributors to carbapenem resistance in biofilm-producing UPEC isolates, highlighting the need for targeted infection control measures.
Phenotypic and molecular characterization of multidrug-resistant Enterobacterales isolated from clinical samples in Palestine: a focus on extended-spectrum β-lactamase- and carbapenemase-producing isolates.
The study identified several AMR genes, including blaTEM, blaSHV, blaCTXm, blaNDM, blaOXA48, and blaKPC, which confer resistance to various beta-lactam antibiotics. These genes were detected in multidrug-resistant Enterobacterales isolates from clinical samples in Palestine.
Carbapenem resistance in gram-negative pathogens in an Iranian hospital: high prevalence of OXA-type carbapenemase genes.
The study identified a high prevalence of OXA-type carbapenemase genes, particularly bla OXA48, bla OXA143, and bla OXA58, among carbapenem-resistant gram-negative bacteria in an Iranian hospital.
Clinical evaluation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections: a prospective study.
The study evaluated a multiplex droplet digital PCR (ddPCR) assay for diagnosing bloodstream infections, identifying key AMR genes such as bla KPC, bla NDM, bla VIM, bla IMP, bla OXA48, vanA, vanM, and mecA in clinical isolates.
Rapid Simultaneous Detection of the Clinically Relevant Carbapenemase Resistance Genes blaKPC, blaOXA48, blaVIM and blaNDM with the Newly Developed Ready-to-Use qPCR CarbaScan LyoBead.
The study introduces the qPCR CarbaScan LyoBead assay, a robust and efficient tool for detecting clinically relevant carbapenemase resistance genes, including blaKPC, blaOXA48, blaVIM, and blaNDM. The assay demonstrated 100% specificity and sensitivity across a diverse range of bacterial strains.
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