Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
type A-10 chloramphenicol O-acetyltransferase
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| H121R | - | - | - | phenicols | Reslit | Candidate |
Mdt(A), a new efflux protein conferring multiple antibiotic resistance in Lactococcus lactis and Escherichia coli.
Research Article
Mdt(A), a new efflux protein conferring multiple antibiotic resistance in Lactococcus lactis and Escherichia coli.
Research Article
Sequence of the 50-kb conjugative multiresistance plasmid pRE25 from Enterococcus faecalis RE25.
Research Article
Sequence of the 50-kb conjugative multiresistance plasmid pRE25 from Enterococcus faecalis RE25.
Research Article
Axe-Txe, a broad-spectrum proteic toxin-antitoxin system specified by a multidrug-resistant, clinical isolate of Enterococcus faecium.
Research Article
Axe-Txe, a broad-spectrum proteic toxin-antitoxin system specified by a multidrug-resistant, clinical isolate of Enterococcus faecium.
Research Article
Axe-Txe, a broad-spectrum proteic toxin-antitoxin system specified by a multidrug-resistant, clinical isolate of Enterococcus faecium.
Research Article
Chloramphenicol resistance transposable element TnSs1 of Streptococcus suis, a transposon flanked by IS6-family elements.
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Chloramphenicol resistance transposable element TnSs1 of Streptococcus suis, a transposon flanked by IS6-family elements.
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Identification and characterization of a shuttle plasmid with antibiotic resistance gene from Staphylococcus aureus.
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Cloning and nucleotide sequence analysis of a chloramphenicol acetyltransferase gene from Vibrio anguillarum.
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Cloning and nucleotide sequence analysis of a chloramphenicol acetyltransferase gene from Vibrio anguillarum.
Research Article
Cloning and nucleotide sequence analysis of a chloramphenicol acetyltransferase gene from Vibrio anguillarum.
Research Article
Nucleotide sequence and structural relationships of a chloramphenicol acetyltransferase encoded by the plasmid pSCS6 from Staphylococcus aureus.
Research Article
Characterization of isolates of Salmonella enterica serovar typhimurium displaying high-level fluoroquinolone resistance in Japan.
Research Article
The study identifies high-level fluoroquinolone-resistant Salmonella enterica serovar Typhimurium isolates with mutations in gyrA (S83F, D87N/G) and parC (S80R), along with resistance genes blaOXA-30, aadA1, dhfr12, aadA2, aac3, catA, and tetRA.
Cloning and sequence analysis of a plasmid-encoded chloramphenicol acetyltransferase gene from Staphylococcus intermedius.
Research Article
Cloning and sequence analysis of a plasmid-encoded chloramphenicol acetyltransferase gene from Staphylococcus intermedius.
Research Article
Occurrence of chloramphenicol resistance and corresponding resistance genes in members of the Staphylococcus sciuri group.
Research Article
Nucleotide sequence and phylogeny of a chloramphenicol acetyltransferase encoded by the plasmid pSCS7 from Staphylococcus aureus.
Research Article
A unified approach to molecular epidemiology investigations: tools and patterns in California as a case study for endemic shigellosis.
Research Article
The study identified the presence of tetB, catA, and blaTEM genes in Shigella isolates, which confer resistance to tetracycline, chloramphenicol, and ampicillin, respectively. These genes were detected through PCR analysis in a significant proportion of the isolates.
Identification of source and sink populations for the emergence and global spread of the East-Asia clone of community-associated MRSA.
Research Article
The study identifies distinct antibiotic resistance gene profiles in Staphylococcus aureus ST59 isolates from the USA and East Asia, with the East Asia clade exhibiting higher resistance to beta-lactams, chloramphenicol, tetracyclines, and macrolides.
Outer Membrane Proteins form Specific Patterns in Antibiotic-Resistant Edwardsiella tarda.
Research Article
The study identifies specific outer membrane protein patterns associated with antibiotic resistance in Edwardsiella tarda, highlighting the role of plasmid-encoded genes such as tetA, tetR, and catA in mediating resistance to tetracycline and chloramphenicol.
Exploring the Genome and Phenotype of Multi-Drug Resistant Klebsiella pneumoniae of Clinical Origin.
Research Article
The study identified multiple antimicrobial resistance genes in 11 multidrug-resistant Klebsiella pneumoniae isolates, including ESBL genes (blaCTX-M-15, blaSHV-12, blaTEM-1B), fluoroquinolone resistance genes (oqxAB, qnrB), and others such as catA, catB, tet, sul, dfr, and fosA. These genes contribute to resistance against various antibiotics, highlighting the complex resistance profile of these isolates.
Serotype Diversity and Antimicrobial Resistance among Salmonella enterica Isolates from Patients at an Equine Referral Hospital.
Research Article
The study identified various AMR genes in Salmonella enterica isolates from equine patients, including beta-lactamases, aminoglycoside modifying enzymes, and genes conferring resistance to tetracyclines, macrolides, and other antibiotics.
The Genomic Basis of Intrinsic and Acquired Antibiotic Resistance in the Genus Serratia.
Research Article
The study identified 123 distinct antibiotic resistance genes (ARGs) in the genus Serratia, including intrinsic and acquired resistance genes, as well as efflux pump-related genes. Key findings include the detection of various beta-lactamases, aminoglycoside resistance genes, quinolone resistance genes, and efflux pumps. Notably, the study highlights the presence of plasmid-borne ARGs in nosocomial strains and the role of efflux pumps in multidrug resistance.
Genomic analysis of Klebsiella pneumoniae isolates from Malawi reveals acquisition of multiple ESBL determinants across diverse lineages.
Research Article
The study identified multiple ESBL genes, including bla CTX-M-15, several bla SHV, bla TEM-63, and bla OXA-10, along with other AMR genes across diverse lineages of K. pneumoniae isolates from Malawi. No carbapenem resistance genes were detected, but plasmids similar to carbapenem resistance-associated plasmid pNDM-mar were found.
Comparative Genomic Analyses Reveal Core-Genome-Wide Genes Under Positive Selection and Major Regulatory Hubs in Outlier Strains of Pseudomonas aeruginosa.
Research Article
The study identified genes under positive selection in Pseudomonas aeruginosa outlier strains, including oprD, which is implicated in carbapenem resistance through reduced uptake.
An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation.
Research Article
The study identifies an extensively drug-resistant (XDR) sublineage II.1 of Salmonella Typhimurium ST313 in the Democratic Republic of the Congo, carrying resistance genes such as catA, blaTEM1, dfrA, blaSHV-2A, mphA, qnrS, and gyrA mutations, along with an IncHI2 plasmid pSTm-ST313-II.1.
Characterization of the First mecA-Positive Multidrug-Resistant Staphylococcus pseudintermedius Isolated from an Argentinian Patient.
Research Article
The study characterizes the first mecA-positive multidrug-resistant Staphylococcus pseudintermedius isolate from an Argentinean patient, identifying several AMR genes and mutations associated with resistance to multiple antibiotics.
Novel Mobilizable Genomic Island GEI-D18A Mediates Conjugational Transfer of Antibiotic Resistance Genes in the Multidrug-Resistant Strain Rheinheimera sp. D18.
Research Article
The study characterizes a novel mobilizable genomic island, GEI-D18A, in the multidrug-resistant strain Rheinheimera sp. D18, which carries several antibiotic resistance genes including aadA1, aacA3, tet(B), catA, dfrA37, and three sul1 genes. The transferability of GEI-D18A was confirmed through mating experiments, demonstrating its role in the conjugational transfer of antibiotic resistance genes.
Prevalence of Cefotaxime-Resistant Escherichia coli Isolates from Healthy Cattle and Sheep in Northern Spain: Phenotypic and Genome-Based Characterization of Antimicrobial Susceptibility.
Research Article
The study identified various AMR genes in cefotaxime-resistant E. coli isolates from cattle and sheep in the Basque Country, including bla CTX-M-14, bla CMY-2, and others, highlighting the prevalence of ESBL and AmpC-producing strains.
A Longitudinal Evaluation of the Bacterial Pathogens Colonizing Chronic Non-Healing Wound Sites at a United States Military Treatment Facility in the Pacific Region.
Research Article
The study identified multiple antimicrobial resistance genes in bacterial isolates from chronic non-healing wounds, including beta-lactamases, aminoglycoside modifying enzymes, macrolide resistance genes, and others. These genes were found in various bacterial species such as E. coli, S. aureus, P. aeruginosa, and others.
Antibiotic resistance plasmid composition and architecture in Escherichia coli isolates from meat.
Research Article
The study characterizes various AMR genes in plasmids from meat-derived E. coli isolates, highlighting the diversity and clustering of resistance genes such as bla CTX-M-1, aadA5, sul2, and others, along with their association with specific plasmid incompatibility groups.
Emerging carbapenem-resistant Klebsiella pneumoniae sequence type 16 causing multiple outbreaks in a tertiary hospital in southern Vietnam.
Research Article
The study identifies carbapenem-resistant Klebsiella pneumoniae sequence type 16 causing multiple outbreaks in a hospital in Vietnam. Key AMR genes include blaOXA-181, blaOXA-48, and mutations in gyrA and parC contributing to fluoroquinolone resistance. Colistin resistance was due to disruption of the mgrB gene by an IS L3-like element.
IncFIB-4.1 and IncFIB-4.2 Single-Replicon Plasmids: Small Backbones with Large Accessory Regions.
Research Article
The study characterizes several AMR genes and mutations in IncFIB-4.1 and IncFIB-4.2 plasmids, highlighting their role in conferring resistance to various antibiotics.
Distribution of ESBL/AmpC-Escherichia coli on a Dairy Farm.
Research Article
The study identified ESBL/AmpC-producing E. coli on a dairy farm, with a high prevalence in calves. Key resistance genes included blaCTX-M-1, blaCTX-M-15, floR, strA, strB, catA, aadA, dfrA, tetA, tetR, tetY, mph(A), and TEM-105.
Farming Practice Influences Antimicrobial Resistance Burden of Non-Aureus Staphylococci in Pig Husbandries.
Research Article
The study found that organic and alternative pig farming practices are associated with reduced antimicrobial resistance (AMR) in non-aureus staphylococci (NAS) compared to conventional farming. Specific AMR genes such as mecA, blaZ, blaPC1, and others were more prevalent in conventional farms, while organic farms showed lower levels of AMR genes for aminoglycosides, phenicols, and tetracyclines.
Intra-host variation of genetic lineages or AMR genotypes of CoPS
Research Article
The study identifies various AMR genes including blaZ, dfrA, dfrG, ermB, catA, aac6′-aph2″, tet(M), dfrK, and ant4′ in Staphylococcus aureus and Staphylococcus pseudintermedius isolates. Additionally, a mutation in grlA (S80F) was found to confer fluoroquinolone resistance.
A Genomic Snapshot of Antibiotic-ResistantEnterococcus faecalis within Public Hospital Environments in South Africa.
Research Article
The study identified tet(M) and erm(B) as the most common antibiotic-resistant genes in Enterococcus faecalis isolates from South African hospitals, along with other resistance genes such as dfrG, catA, and optrA.
Genomic Features of Antimicrobial Resistance in Staphylococcus pseudintermedius Isolated from Dogs with Pyoderma in Argentina and the United States: A Comparative Study.
Research Article
The study identified various antimicrobial resistance genes and mutations in Staphylococcus pseudintermedius isolates from dogs in Argentina and the United States, highlighting differences in resistance profiles between the two regions.
Genetic characterization of MDR genomic elements carrying two aac(6')-aph(2") genes in feline-derived clinical Enterococcus faecalis isolate.
Research Article
The study identified a multidrug-resistant E. faecalis isolate (ESC1) carrying a novel composite transposon with two aac(6')-aph(2") genes, along with several other resistance genes on plasmids, contributing to resistance against multiple antibiotics.
Genetic Diversity and Antimicrobial Resistance of Extraintestinal E. coli Populations Pre- and Post-Antimicrobial Therapy on Broilers Affected by Colisepticemia.
Research Article
The study identified several AMR genes and mutations in extraintestinal E. coli populations from broilers treated with enrofloxacin. Key findings include the presence of qnrB19 and qnrS1 genes, which confer fluoroquinolone resistance, and mutations in gyrA, parC, and parE genes associated with fluoroquinolone resistance. Additionally, multiple other AMR genes were detected, indicating multidrug resistance.
Identification of knowledge gaps in whole-genome sequence analysis of multi-resistant thermotolerant Campylobacter spp.
Research Article
The study identified 22 different resistance genes and gene variants, including erm(B), aph(3')-IIIa, aadE, catA, lnu(C), blaOXA, sat4, tet(O), and point mutations in gyrA, 23S rRNA, and rpsL, associated with antimicrobial resistance in thermotolerant Campylobacter spp.
Chloramphenicol acetyltransferase gene of staphylococcal plasmid pC221. Nucleotide sequence analysis and expression studies.
Research Article
Chloramphenicol acetyltransferase gene of staphylococcal plasmid pC221. Nucleotide sequence analysis and expression studies.
Research Article
Regulation of the inducible chloramphenicol acetyltransferase gene of the Staphylococcus aureus plasmid pUB112.
Research Article
Multidrug-resistant Escherichia coli causing canine pyometra and urinary tract infections are genetically related but distinct from those causing prostatic abscesses.
Research Article
The study identifies multiple AMR genes and mutations in multidrug-resistant E. coli strains causing infections in dogs and cats, including bla CTX-M-14, bla CTX-M-15, bla CTX-M-27, bla CTX-M-55, bla CMY-2, bla CMY-148, aac(6')-Ib-cr, qnrS1, qnrB6, aadA2, aadA5, aadA16, ant(3′′)-Ia, aph(3′)-Ia, aph(3′′)-Ib, aph(6)-Id, rmtB, floR, cmlA, catA, sul1, sul2, sul3, dfrA12, dfrA14, dfr17, dfrA27, tet(A), tet(B), tet(M), mph(A), erm(B), lnu(F), and arr-3, as well as the gyrA:p.S83L mutation.
Molecular basis of the persistence of chloramphenicol resistance among Escherichia coli and Salmonella spp. from pigs, pork and humans in Thailand.
Research Article
The study identifies catA and cmlA as the primary genes responsible for chloramphenicol resistance in E. coli and Salmonella isolates from Thailand, highlighting their persistence through co-selection and horizontal gene transfer.
Genomic profiling of pan-drug resistant proteus mirabilis Isolates reveals antimicrobial resistance and virulence gene landscape.
Research Article
The study identified multiple antimicrobial resistance genes in pan-drug resistant Proteus mirabilis isolates, including genes conferring resistance to aminoglycosides, beta-lactams, tetracyclines, sulfonamides, and others. These genes were found on the chromosome and contributed to the isolates' resistance to various antibiotic classes.
Culture and amplification-free nanopore sequencing for rapid detection of pathogens and antimicrobial resistance genes from urine.
Research Article
The study demonstrates the successful detection of various antimicrobial resistance genes, including blaCTX-M-15, blaCTX-M-2, blaTEM-1, blaSHV, catA, tet(J), blaOXA-356, fosB, and mepA, using nanopore sequencing in spiked urine samples.
Providencia pseudovermicola sp. nov.: redefining Providencia vermicola and unveiling multidrug-resistant strains from diabetic foot ulcers in Egypt.
Research Article
The study identifies multiple multidrug-resistant genes in Providencia pseudovermicola sp. nov., including bla CTX-M-14, bla CMY-6, bla NDM-1, qnrD1, aadA, armA, msrE, mphE, lnuF, rmtC, aac(6')-Ib10, sul1, aph(3')-Ia, qacEΔ1, and dfrA1, highlighting the significance of these genes in conferring resistance to various antibiotics.
Genomic analysis of Salmonella enterica from cattle, beef and humans in the Greater Tamale Metropolis of Ghana.
Research Article
Four raw beef isolates harbored at least one gene conferring resistance to beta-lactam (blaTEM-1), chloramphenicol (catA), fosfomycin (fosA7), quinolone (qnrD1), or tetracycline (tet(A)).
Retrospective analysis of antimicrobial resistance of Salmonella spp. isolated from livestock and its environment in Thailand.
Research Article
The study identified several AMR genes in Salmonella isolates from livestock and their environment in Thailand, including aadA1, aadA2, aadB, aac(6')-Ia, blaTEM, tetA, tetB, catA, catB, cmlA, sulI, and dfrA1, which confer resistance to various antibiotics such as aminoglycosides, beta-lactams, tetracyclines, chloramphenicol, sulfamethoxazole, and trimethoprim.
Comparative genomics of Pseudomonas paraeruginosa.
Research Article
The study identifies various AMR genes and mutations in Pseudomonas paraeruginosa, including carbapenemases like blaVIM-2, blaVIM-6, blaVIM-28, and blaKPC-2, as well as efflux pump genes (mexAB-oprM, mexCD-oprJ, etc.), and mutations in oprD, mexS, mexR, mexZ, lasR, mvfR, and vqsM that contribute to antibiotic resistance.
Epidemiology of potential source, risk attribution of Clostridium perfringens from Egyptian broiler farms and genetic diversity of multidrug resistance strains.
Research Article
The study identified multiple AMR genes in Clostridium perfringens isolates from Egyptian broiler farms, including aminoglycoside, beta-lactam, macrolide, quinolone, sulfonamide, tetracycline, and trimethoprim resistance genes. High prevalence of multidrug-resistant strains was observed.
Epidemiology of potential source, risk attribution of Clostridium perfringens from Egyptian broiler farms and genetic diversity of multidrug resistance strains.
Research Article
The study identified multiple AMR genes in Clostridium perfringens isolates from Egyptian broiler farms, including aminoglycoside, beta-lactam, macrolide, quinolone, sulfonamide, tetracycline, and trimethoprim resistance genes. High prevalence of multidrug-resistant strains was observed.
Structural basis for antibiotic resistance by chloramphenicol acetyltransferase type A in Staphylococcus aureus.
Research Article
The study characterizes saCAT1, a type-A chloramphenicol acetyltransferase from Staphylococcus aureus, which confers resistance to chloramphenicol through enzymatic inactivation. The structural and biochemical analysis reveals the molecular basis of its catalytic activity and substrate specificity.
Plasmid-Mediated Spread of Antibiotic Resistance by Arsenic and Microplastics During Vermicomposting.
Research Article
Arsenic and microplastics significantly influenced the spread of antibiotic resistance genes (ARGs) during vermicomposting, with specific genes like bla ampC, bla LRA-1, bla FEZ-1, aph(3′)-II, ermB, vanY, mefA, catA, tetX4, bla IMP-11, aadK, ant(3′)-Ih-aac(6′)-Id, ermG, bla OXA-119, tetR, vatE, smeE, mexD, bla OXA-3, amrB, tetY, class A beta-lactamase, dfrA1, alanine adenosyltransferase JOHN-1, mdtB, mdtE, and erm-41 being enriched under various treatment conditions.
Genomic and Phenotypic Landscape of Antibiotic Resistance in Gut Lactic Acid Bacteria from Livestock Environments.
Research Article
The study identified multiple antibiotic resistance genes in lactic acid bacteria (LAB) from livestock environments, including van(T), erm(B), cat(A), tet(W), lsa(D), arr, van(Y), and qac(G). These genes conferred resistance to various antibiotics, highlighting the potential for horizontal gene transfer and the importance of monitoring LAB for AMR.
Nucleotide sequence and functional map of pC194, a plasmid that specifies inducible chloramphenicol resistance.
Research Article
Nucleotide sequence and functional map of pC194, a plasmid that specifies inducible chloramphenicol resistance.
Research Article
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