The study identifies several AMR genes in multidrug-resistant Gram-negative bacteria isolated from German surface waters, highlighting the presence of clinically relevant resistance mechanisms such as bla CTX-M-1, bla CTX-M-15, mcr-1, and others.

The study reports the first autochthonous extensively drug-resistant NDM-1 Pseudomonas aeruginosa ST235 strain in Italy, highlighting the presence of multiple beta-lactamase genes, aminoglycoside modifying enzymes, and multidrug efflux pumps contributing to its extensive drug resistance.

The study identified multiple antimicrobial resistance genes in Aeromonas veronii strain MS-17-88, including beta-lactamase genes (imiS, ampS), phenicol resistance genes (floR, catB2, catB7, vat(F)), colistin resistance genes (mcr-3, mcr-7.1), tetracycline resistance genes (tet(34), tet(35), tet(E)), and a trimethoprim resistance gene (dfrA3).

The study compared hybrid assembly approaches for bacterial pathogen genomes and identified AMR genes such as blaZ, msr(A), and tet(K) in Staphylococcus aureus.

The study identifies multiple AMR genes in a multidrug-resistant Pseudomonas aeruginosa strain, including beta-lactamases (blaVEB-9, blaOXA-10, blaOXA-50, blaPDC-11), aminoglycoside resistance genes (aph(3')-IIb, aac(6')-Il, ant(2'')-Ia), fluoroquinolone resistance gene (crpP), phenicol resistance gene (catB7), and tetracycline resistance gene (tet(A)).

The study identified multiple antimicrobial resistance genes in bacterial isolates from chronic non-healing wounds, including beta-lactamases, aminoglycoside modifying enzymes, macrolide resistance genes, and others. These genes were found in various bacterial species such as E. coli, S. aureus, P. aeruginosa, and others.

The study identified various carbapenemase genes (blaNDM-1, blaNDM-5, blaVIM-1, blaVIM-6, blaOXA-23, blaOXA-58, blaOXA-66, blaOXA-69, blaOXA-91, blaOXA-181, blaOXA-50) and other resistance genes (such as armA, rmtC, rmtF, aac(3)-I, aadA1, aph(3')-Ia, aph(3')-VI, aph(3')-Via, aph(6')-Id, mphE, msrE, mphA, ereA, dfrA1, dfrA12, dfrA14, dfrA17, dfrA20, sul1, sul2, tetB, tetD, tetG, tet39, qnrVC1, qnrS1, qnrB4, floR, catA1, catA2, catB3, catB7, cmlA1, cmlA5, arr-3, arr-2, sat2, acrF, mdtM, emrD, mexA, mexE, mexX, kdeA, oxa-10, oxa-395, oxa-396, oxa-846, adc-25, dha-1, act-16, cmY, ctx-m-15, shv-67, tem-1b) in carbapenem non-susceptible clinical isolates of gram-negative bacteria in Kenya, highlighting the diversity and prevalence of multidrug resistance.

The study presents a DNA microarray-based assay for the simultaneous detection of 44 sepsis-relevant bacterial pathogens, 360 virulence factors, and 409 antibiotic resistance genes. The assay was evaluated with 14 multidrug-resistant strains, including all ESKAPE pathogens.

The study identified various AMR genes and mutations in Gram-negative bacteria isolated from chronic wounds in Ghana, including beta-lactamases, fosfomycin resistance genes, chloramphenicol resistance genes, aminoglycoside resistance genes, fluoroquinolone resistance genes, tetracycline resistance genes, sulfonamide resistance genes, trimethoprim resistance genes, and efflux pumps. Mutations in gyrA, parE, and parC were also found to contribute to fluoroquinolone resistance.

The study identifies several antimicrobial resistance genes in a genetically adapted Pseudomonas aeruginosa isolate from a COVID-19 patient, including aph(3')-IIb, blaOXA-395, blaPAO, fosA, and catB7, which confer resistance to aminoglycosides, beta-lactams, fosfomycin, and phenicols.

The study identified various AMR genes and mutations in P. aeruginosa isolates from a CF patient, including beta-lactamases, aminoglycoside-modifying enzymes, fluoroquinolone resistance genes, and mutations in regulatory and structural genes contributing to resistance against multiple antibiotics.

The study identifies bla(VIM-2) and bla(KPC-2) genes in multidrug-resistant Pseudomonas aeruginosa isolates from Colombia, highlighting their diverse genetic environments and mechanisms of resistance.

The study identifies NDM-1 and VIM-2 co-producing E. coli and OprD alterations in P. aeruginosa, highlighting the emergence of multidrug-resistant Gram-negative bacteria in hospital environments in Tunisia.

The study identifies various AMR genes and mutations in P. aeruginosa isolates from dogs and cats in Japan, highlighting the presence of high-risk clones like ST235 and the role of genetic factors in carbapenem and fluoroquinolone resistance.

The study identified multiple antibiotic resistance genes in clinical Pseudomonas aeruginosa isolates, including blaVIM-2, blaOXA-396, blaOXA-488, floR, tetG, sul1, dfrA5, dfrB2, dfrB5, aph(3)-Ib, blaPAO, catB7, and fosA, which confer resistance to various antibiotics such as beta-lactams, chloramphenicol, tetracycline, sulfonamides, trimethoprim, aminoglycosides, and fosfomycin.

The study identified 13 acquired antibiotic resistance genes in six new sequence types of multidrug-resistant Pseudomonas aeruginosa isolates from Pakistan, including beta-lactamases, aminoglycoside-modifying enzymes, and others. Mutations in the pmrA gene were also found to contribute to colistin resistance.

The study identified several antimicrobial resistance genes in Pseudomonas aeruginosa colonizing isolates, including bla OXA-50, aph(3′)-IIb, fosA, bla PAO, catB7, and crpP, which confer resistance to beta-lactam, aminoglycoside, fosfomycin, chloramphenicol, and ciprofloxacin. A novel sequence type ST-3910 was also reported.

The study identified multiple AMR genes and efflux pump systems in P. aeruginosa persister isolates, highlighting their multidrug-resistant phenotype and biofilm-forming capabilities.

The study identifies multiple antibiotic resistance genes (ARGs) in bla NDM-1 -positive P. aeruginosa ST308 isolates, including aac(3)-Id, aac(6′)-Il, aph(3′)-Iib, bla OXA-488, bla NDM-1, bla PDC-19a, catB7, crpP, fosA, msr(E), qnrVC1, sul2, dfrB5, floR, aadA6, aadA11, and aph(3″)-Ib. These genes confer resistance to various antibiotics such as aminoglycosides, beta-lactams, carbapenems, cephalosporins, chloramphenicol, fluoroquinolones, fosfomycin, macrolides, quinolones, sulfonamides, trimethoprim, and streptomycin.

The study reports the first detection of blaNDM-1-positive Pseudomonas aeruginosa ST308 in Greece, highlighting the presence of multiple resistance genes including blaNDM-1, blaPAO, blaOXA-10, blaOXA-488, and others, indicating multidrug resistance.

The study reports a case of domestically acquired NDM-1-producing Pseudomonas aeruginosa in a transplant patient in southern California, highlighting the presence of multiple resistance genes including blaNDM-1, blaOXA-10, blaOXA-488, blaPDC-35, blaPME-1, aac(6')-Ib9, ant(3”)-IIa, aph(3′)-IIb, aph(3′)-VIa, catB3, catB7, cmlA9, fosA, tet(D), and sul1.

The study identified multiple AMR genes and mutations in Pseudomonas aeruginosa isolates from catheter-associated urinary tract infections in Egypt, including beta-lactamases, aminoglycoside-modifying enzymes, quinolone resistance proteins, and efflux pump systems. Additionally, a pBT2436-like megaplasmid was detected, which contributes to multidrug resistance.

The study identifies high levels of antibiotic resistance in respiratory tract bacteria from patients with antibody deficiency, particularly macrolide resistance genes erm(B) and mef(A), and highlights the role of commensal streptococci as reservoirs for resistance genes.

Low-dose ozone nanobubble treatments increased the relative abundance of antimicrobial resistance genes (ARGs) in pond water, particularly those associated with efflux pumps and beta-lactam resistance.

The study identifies the presence of the blaIMP-1 gene within the Tn6411 transposon in Pseudomonas aeruginosa strains, along with aacC2 and catB7, contributing to resistance against carbapenems, aminoglycosides, and chloramphenicol.

The study identifies the NDM-1-producing Pseudomonas aeruginosa ST357 as an extensively drug-resistant strain with a unique resistome, highlighting the importance of tracking the origin of such isolates through genomic epidemiology.

The study identified multiple AMR genes, including blaDIM-1, qacE, and various efflux pump genes, in bacterial isolates from hospital disinfectants, indicating their adaptation to survive in disinfectant environments.

The study identified multiple AMR genes, including blaVEB-9, blaPDC-3, blaOXA-10, blaOXA-50, and others, in two extensively drug-resistant Pseudomonas aeruginosa isolates from Bulgaria. These genes conferred resistance to various antibiotics, including β-lactams, aminoglycosides, and fluoroquinolones.

The study identified multiple antibiotic resistance genes in Pseudomonas aeruginosa clinical isolates, including bla PDC, bla OXA, and bla VIM, which confer resistance to beta-lactams, as well as aac(6')-Il, aadA10, aph, and others that confer resistance to aminoglycosides. Additionally, genes like catB7, fosA, qnrVC1, and crpP were found to confer resistance to chloramphenicol, fosfomycin, quinolones, and fluoroquinolones, respectively.

The study identifies multiple AMR genes in the MDR P. aeruginosa strain U804, including beta-lactamases, aminoglycoside modifying enzymes, and efflux pumps, which contribute to its resistance against various antibiotics.

The study identified several antibiotic resistance genes in Pseudomonas aeruginosa S-8, including beta-lactamases (ampC, blaTEM, blaSHV, blaCTX-M), efflux pump components (mexB, mexA, oprM, acrB, tolC), and a transcriptional regulator (ampR). These genes contribute to resistance against various antibiotics such as beta-lactams, tetracycline, chloramphenicol, and fluoroquinolones.

MultiSeq-AMR is a rapid and modular nanopore amplicon-sequencing workflow that accurately detects bacterial and fungal species and a comprehensive set of antimicrobial resistance (AMR) genes from various infection sources. It exhibits high accuracy in identifying AMR genes, with 99.4% categorical agreement with whole-genome sequencing and 97.4% accuracy for AMR gene prediction in BACT/ALERT positive samples.

The study identifies various acquired antibiotic resistance genes in Pseudomonas spp., Escherichia coli, and Acinetobacter spp. in the Western Balkans and Hungary, including beta-lactamases like bla VIM-2-like, bla NDM-1, bla OXA-23, and bla OXA-66, aminoglycoside resistance genes such as aacA4, aadA2, and aphA, sulfonamide resistance gene sul1, and others. These genes confer resistance to multiple antibiotics, highlighting the complexity of antimicrobial resistance in the region.

The study identified several AMR genes and mutations in colistin-resistant P. aeruginosa isolates, including blaNDM-1, blaOXA-1028, blaOXA-904, and mutations in phoQ and basR genes associated with colistin resistance.

The study identified five AMR genes in a multidrug-resistant Pseudomonas aeruginosa isolate from peregrine falcons in Saudi Arabia, highlighting the zoonotic potential and the need for integrated AMR surveillance.