Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
type B-3 chloramphenicol O-acetyltransferase CatB8
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| CatB8 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 37 | CHLORAMPHENICOL, Chloramphenicol +1 |
| China, China|Beijing, China, Los Angeles County, California, USA|Los Angeles County, Thailand|Nepal, South Korea, Vietnam|Southeast Asia, Egypt, United States, northwest China, Alexandria, Egypt, Fiji, Cambodia, Europe, China|North America|Asia|Europe|Africa|Other, Egypt|Tunisia|Middle East|North Africa, Iran |
| 2003, 2012, 2013, 2016, 2018, 2019, 2020, 2021, 2022, 2023, 2024, 2025 |
| AF227506.1 |
| AAF61918.1 |
| catB8 | Card DatabaseResFinder Database | 2 | CHLORAMPHENICOL | Klebsiella pneumoniae +1 | - | 2003 | AF227506 | AAM92461.1 |
Salmonella enterica serovar typhi strains isolated in Korea containing a multidrug resistance class 1 integron.
Salmonella enterica serovar typhi strains isolated in Korea containing a multidrug resistance class 1 integron.
Salmonella enterica serovar typhi strains isolated in Korea containing a multidrug resistance class 1 integron.
Salmonella enterica serovar typhi strains isolated in Korea containing a multidrug resistance class 1 integron.
Novel gene cassettes and integrons in antibiotic-resistant bacteria isolated from urban wastewaters.
Analysis of antibiotic resistance in bacteria isolated from the surface microlayer and underlying water of an estuarine environment.
Clonal spread of carbapenem non-susceptible Acinetobacter baumannii in an intensive care unit in a teaching hospital in China.
The study identifies blaOXA-23 as the primary carbapenem resistance determinant in Acinetobacter baumannii isolates, alongside aacA4, catB8, and aadA1 contributing to aminoglycoside and chloramphenicol resistance. The clonal complex CC92, particularly ST92 and ST75, was prevalent in carbapenem-non-susceptible isolates.
Complete sequence of pOZ176, a 500-kilobase IncP-2 plasmid encoding IMP-9-mediated carbapenem resistance, from outbreak isolate Pseudomonas aeruginosa 96.
Complete genome analysis of three Acinetobacter baumannii clinical isolates in China for insight into the diversification of drug resistance elements.
The study identifies multiple AMR genes and resistance islands in three multidrug-resistant Acinetobacter baumannii isolates, highlighting the role of genomic plasticity in the dissemination of resistance mechanisms.
Molecular characterization and antimicrobial susceptibility of Acinetobacter baumannii isolates obtained from two hospital outbreaks in Los Angeles County, California, USA.
The study identified multiple AMR genes including blaOXA-23, blaOXA-51-like, aacA4, catB8, and aadA1, along with mutations in gyrA and parC genes, which are associated with resistance to carbapenems, fluoroquinolones, and aminoglycosides in Acinetobacter baumannii isolates from two hospital outbreaks.
Impact of Wastewater Treatment on the Prevalence of Integrons and the Genetic Diversity of Integron Gene Cassettes.
The study identified various antibiotic resistance genes within integron gene cassettes in wastewater treatment plants, including aadA1, aadA2, aadA5, blaOXA-1, blaOXA-10, blaOXA-101, blaOXA-129, blaOXA-21, blaOXA-28, catB8, dfrA14, erm, qacE2, sul1, tet, orfD, and orfA, which confer resistance to aminoglycosides, beta-lactams, chloramphenicol, trimethoprim, sulfonamides, tetracyclines, and quaternary ammonium compounds.
First Report of Coexistence of Three Different MDR Plasmids, and That of Occurrence of IMP-Encoding Plasmid in Leclercia adecarboxylata.
The study reports the first identification of three different multidrug-resistant (MDR) plasmids in a single clinical isolate of Leclercia adecarboxylata, including the blaIMP-8 gene encoded on an IMP-encoding plasmid. These plasmids harbor various AMR genes such as blaIMP-8, aacC2, aadA2, mph(A), sul1, qacED1, mer, chrA, dfrA12, tmrB, catA1, catB8, tet(C), blaCTX-M-9, and blaTEM-1.
Genomic analysis reveals high virulence and antibiotic resistance amongst phage susceptible Acinetobacter baumannii.
The study identified multiple antibiotic resistance genes in phage-susceptible Acinetobacter baumannii strains, including sulfonamide, tetracycline, beta-lactam, aminoglycoside, macrolide, and phenicol resistance genes. These findings highlight the complex resistance profiles of these strains and their potential implications for therapeutic strategies.
Genomic and phenotypic analyses of multidrug-resistant Acinetobacter baumannii NCCP 16007 isolated from a patient with a urinary tract infection.
The study identifies multiple AMR genes and mutations in the multidrug-resistant A. baumannii NCCP 16007 strain, including pmrC, pmrB, blaOXA-23, and various aminoglycoside, tetracycline, and beta-lactam resistance genes, contributing to its high resistance to polymyxin B and other antibiotics.
WGS-Based Analysis of Carbapenem-Resistant Acinetobacter baumannii in Vietnam and Molecular Characterization of Antimicrobial Determinants and MLST in Southeast Asia.
The study identified several AMR genes in carbapenem-resistant Acinetobacter baumannii strains from Vietnam, including bla OXA-51-like, bla OXA-23, bla TEM-1, and others, highlighting the widespread resistance to beta-lactams, aminoglycosides, and other antibiotics.
Deciphering Multidrug-Resistant Acinetobacter baumannii from a Pediatric Cancer Hospital in Egypt.
The study identified various AMR genes and mutations in multidrug-resistant Acinetobacter baumannii isolates from a pediatric cancer hospital in Egypt, highlighting the presence of bla NDM, bla OXA-23-like, bla OXA-51-like, and other resistance genes, along with mutations in pmrA and lptF contributing to colistin resistance.
Mouse pneumonia model by Acinetobacter baumannii multidrug resistant strains: Comparison between intranasal inoculation, intratracheal instillation and oropharyngeal aspiration techniques.
The study identified various AMR genes in two multidrug-resistant Acinetobacter baumannii strains, ACC001 and ACC002, including aminoglycoside resistance genes, tetracycline resistance genes, beta-lactamases, and sulfonamide resistance genes. These genes contribute to resistance against multiple antibiotics such as gentamicin, tobramycin, tetracycline, penicillins, cephalosporins, and sulfonamides.
Genomic Characterization of Extensively Drug-Resistant NDM-Producing Acinetobacter baumannii Clinical Isolates With the Emergence of Novel bla (ADC-257).
The study identified several AMR genes, including novel bla ADC-257, and mutations in gyrA and parC associated with fluoroquinolone resistance in extensively drug-resistant NDM-producing Acinetobacter baumannii isolates.
Carbapenem-Resistant Acinetobacter baumannii in U.S. Hospitals: Diversification of Circulating Lineages and Antimicrobial Resistance.
The study identifies multiple carbapenemase genes, including blaOXA-23 and blaOXA-207, as well as various resistance islands harboring genes such as aacA4, catB8, and armA, contributing to the multidrug resistance of CR Ab isolates in U.S. hospitals.
Molecular epidemiology and carbapenem resistance characteristics of Acinetobacter baumannii causing bloodstream infection from 2009 to 2018 in northwest China.
The study identified multiple carbapenem resistance genes, including blaOXA-23 and blaOXA-72, along with other resistance mechanisms such as 16S rRNA methylase armA and aminoglycoside-modifying enzymes. The AdeABC efflux pump was also found to contribute to carbapenem resistance.
Conjugation of plasmid harboring bla (NDM-1) in a clinical Providencia rettgeri strain through the formation of a fusion plasmid.
The study identifies multiple AMR genes, including blaNDM-1, blaOXA-10, blaPER-4, aph(3')-VI, ant(2'')-Ia, ant(3')-Ia, sul1, catB8, catA1, mph(E), and tet, in a multidrug-resistant Providencia rettgeri strain. These genes contribute to resistance against various antibiotics, including carbapenems, beta-lactams, aminoglycosides, sulfonamides, chloramphenicol, macrolides, and tetracyclines.
Molecular characterization of multidrug resistant Acinetobacter baumannii clinical isolates from Alexandria, Egypt.
The study identified various AMR genes in multidrug-resistant Acinetobacter baumannii isolates from Alexandria, Egypt, including bla OXA-51-like variants, bla OXA-23, bla NDM-1, bla PER-7, bla GES-like, and others, highlighting the widespread resistance to beta-lactams, aminoglycosides, tetracyclines, and other antibiotics.
Whole-genome sequencing and analysis of Chryseobacterium arthrosphaerae from Rana nigromaculata.
The study identified 10 antibiotic resistance genes in Chryseobacterium arthrosphaerae strain FS91703, including genes conferring resistance to folate pathway inhibitors, penicillins, cephalosporins, carbapenems, phenicols, tetracyclines, and erythromycin. Additionally, two multidrug-resistant efflux pump genes, adeG and farA, were detected.
Molecular and clinical epidemiology of carbapenem resistant Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacterales in Fiji: a multicentre prospective observational study.
The study identified several carbapenem-resistant genes, including bla OXA-23, bla OXA-66, bla NDM-1, bla OXA-50, bla OXA-395, bla NDM-7, and bla NDM-5, in various bacterial species in Fiji.
Bacterial Genomics for National Antimicrobial Resistance Surveillance in Cambodia.
The study identified various AMR genes and mutations in bacterial isolates from Cambodia, including extended-spectrum beta-lactamase genes (blaCTX-M-15, blaCTX-M-27, blaCTX-M-55), carbapenemase genes (blaOXA-23, blaNDM-1, blaOXA-58, blaOXA-66), and colistin resistance genes (mcr-1, mcr-3, mcr-7, mcr-9). Additionally, mutations in gyrA (S83F) and parC (S84L) were found to confer fluoroquinolone resistance in Salmonella enterica serovars Paratyphi A and Typhi.
Environmental contamination with carbapenem resistant Acinetobacter baumannii in healthcare settings in Fiji: a potential source of infection.
The study identified several carbapenem-resistant Acinetobacter baumannii (CR Ab) isolates from high-touch surfaces in Fijian hospitals, revealing the presence of resistance genes such as bla OXA-23, bla NDM-1, and others, along with mutations in genes like parC and gyrA, contributing to resistance against multiple antibiotics.
A decade of genomic and phenotypic adaptation of carbapenem-resistant Acinetobacter baumannii.
The study identifies various AMR genes and mutations in carbapenem-resistant Acinetobacter baumannii isolates, including blaOXA-23, blaOXA-51-like, and several aminoglycoside resistance genes, contributing to extensive drug resistance.
Genomic insights into bacteriophages: a new frontier in AMR detection and phage therapy.
The paper discusses the identification of various AMR genes in Acinetobacter baumannii and other pathogens, highlighting their role in resistance to multiple antibiotics and the potential of phage therapy as an alternative treatment.
Global phylogeography and genomic characterization of bla(NDM-1)-positive clinical Proteus mirabilis isolates from China.
The study identifies blaNDM-1 as a key determinant of carbapenem resistance in Proteus mirabilis isolates from China, along with other resistance genes such as blaCTX-M-14, blaCTX-M-65, and blaTEM-1. It also characterizes the genomic context of blaNDM-1, including its integration into SGI1 and plasmid-borne elements.
Genomic insights into ST85 and ST158 belonging to recently emerged global clones of multidrug-resistant Acinetobacter baumannii isolates from Egypt: in vitro assessment of repurposed drug-antibiotic combinations.
The study identified multiple antibiotic resistance genes, including blaOXA-23, aadA1, armA, aph(3')-VIa, aph(3')-Ia, and ant(3'')-IIa, in multidrug-resistant Acinetobacter baumannii isolates from Egypt.
Genetic features of bla(NDM-1) harboring Klebsiella pneumoniae isolates from Kerman, Iran.
The study identifies bla(NDM-1) as a key carbapenem resistance gene in Klebsiella pneumoniae isolates from Kerman, Iran, highlighting its role in multidrug resistance and the need for monitoring its spread.
Distribution characteristics of integrons and correlation analysis of antibiotic resistance in Aeromonas hydrophila.
Class 1 integrons carrying the aminoglycoside resistance gene aadA1 and the chloramphenicol resistance gene catB8 were identified in Aeromonas hydrophila clinical isolates, directly associated with corresponding antibiotic resistance phenotypes.
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