cft2

predicted bifunctional protein

Validation StatusCandidate

Overview

Mechanism: confers resistance to ceftazidime through a β-lactamase domain
Validation Method: cloning in E. coli + antibiotic susceptibility assays
Drug Classes: Ceftazidime
Organisms: Escherichia coli
Geographic Location: Wisconsin
Papers: 1
Databases: Reslit

Papers1

Metagenomic analysis of apple orchard soil reveals antibiotic resistance genes encoding predicted bifunctional proteins.

PMID 20453147 · 2010

The study identifies two novel bifunctional antibiotic resistance genes, cft2 and kan4, which confer resistance to ceftazidime and kanamycin, respectively. These genes encode proteins with distinct domains that contribute to resistance mechanisms.

Gene Information

Gene Name: cft2
Allele: cft2
Encodes: predicted bifunctional protein
Source Database: Reslit
Mechanism: confers resistance to ceftazidime through a β-lactamase domain
Confers Resistance To: Ceftazidime
Organisms Tested In: • Escherichia coli
Geographic Location: Wisconsin
Validation Method: cloning in E. coli + antibiotic susceptibility assays
Sequence Accession: AOAmox2|AOCarb3|AOCefta2|AOAmox1|AOCarb11|AOCefta11|AOPip4|AOCarb2|AOCefta1|AOKan4|AOKan6|AOKan8|AOTet43

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cft2

Gene Information