cmlA5

chloramphenicol acetyltransferase

Validation StatusCandidate

Overview

Mechanism: nonenzymatic chloramphenicol resistance
Validation Method: cloning in E. coli and MIC testing
Drug Classes: chloramphenicol
Organisms: Escherichia coli
Papers: 1
Databases: Reslit

Papers1

Characterization of In53, a class 1 plasmid- and composite transposon-located integron of Escherichia coli which carries an unusual array of gene cassettes.

PMID 11114922 · 2001

The study characterizes In53, a unique class 1 integron in Escherichia coli that carries multiple antibiotic resistance gene cassettes, including aadB, arr-2, cmlA5, qacI, aacA1b/orfG, oxa10, and aadA1, each contributing to resistance against various antibiotics.

Gene Information

Gene Name: cmlA5
Allele: CmlA5
Encodes: chloramphenicol acetyltransferase
Source Database: Reslit
Mechanism: nonenzymatic chloramphenicol resistance
Confers Resistance To: chloramphenicol
Organisms Tested In: • Escherichia coli
Validation Method: cloning in E. coli and MIC testing
Sequence Accession: AF205943

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cmlA5

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