Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
chloramphenicol efflux MFS transporter Cmx
Overview
The 51,409-bp R-plasmid pTP10 from the multiresistant clinical isolate Corynebacterium striatum M82B is composed of DNA segments initially identified in soil bacteria and in plant, animal, and human pathogens.
The 51,409-bp R-plasmid pTP10 from the multiresistant clinical isolate Corynebacterium striatum M82B is composed of DNA segments initially identified in soil bacteria and in plant, animal, and human pathogens.
Under the influence of the active deodorant ingredient 4-hydroxy-3-methoxybenzyl alcohol, the skin bacterium Corynebacterium jeikeium moderately responds with differential gene expression.
Dermabacter hominis: a usually daptomycin-resistant gram-positive organism infrequently isolated from human clinical samples.
The study characterizes the antimicrobial resistance profile of Dermabacter hominis, identifying resistance to daptomycin, erythromycin, clindamycin, and other antibiotics. It also identifies specific genes associated with resistance, including erm(X), cmx, strAB, sul1, and a mutation in gyrA linked to fluoroquinolone resistance.
Complete Genome Sequence of Corynebacterium imitans DSM 44264, Isolated from a Five-Month-Old Boy with Suspected Pharyngeal Diphtheria.
The genome of Corynebacterium imitans DSM 44264 reveals the presence of several antibiotic resistance genes, including erm(X), aphA1-IAB, strA-strB, and cmx, which are consistent with its multidrug-resistant profile.
Characterization and antimicrobial susceptibility of one antibiotic-sensitive and one multidrug-resistant Corynebacterium kroppenstedtii strain isolated from patients with granulomatous mastitis.
The study identified multidrug-resistant Corynebacterium kroppenstedtii strain CNM633/14 carrying resistance genes erm(X), tet(W), cmx, aphA1-IAB, strAB, and sul1, which confer resistance to various antibiotics including erythromycin, clarithromycin, azithromycin, clindamycin, tetracycline, chloramphenicol, kanamycin, streptomycin, and cotrimoxazole.
Intraclonal Genome Stability of the Metallo-β-lactamase SPM-1-producing Pseudomonas aeruginosa ST277, an Endemic Clone Disseminated in Brazilian Hospitals.
The study identifies the blaSPM-1 gene as a key factor in carbapenem resistance in Pseudomonas aeruginosa ST277 isolates, along with other resistance genes in genomic islands.
Dissemination of antibiotic resistance genes from antibiotic producers to pathogens.
The study provides evidence for the transfer of antibiotic resistance genes from actinobacteria to proteobacteria, highlighting the role of the 'carry-back' mechanism in the dissemination of resistance genes such as cmx and lmrA.
Genome sequence of a multidrug-resistant Corynebacterium striatum isolated from bloodstream infection from a nosocomial outbreak in Rio de Janeiro, Brazil.
The study reports the draft genome of a multidrug-resistant Corynebacterium striatum isolate, identifying several resistance genes including tetA, tetB, vanW, ermX, aph(3')-Ia, strA-strB, bla, and cmx, along with a mutation in the gyrA gene contributing to quinolone resistance.
Virulence Characteristics and an Action Mode of Antibiotic Resistance in Multidrug-Resistant Pseudomonas aeruginosa.
The study identifies several AMR genes including aadB, aac(6')-31, aph(3')-VIa, blaOXA-1, sul1, and cmx in multidrug-resistant Pseudomonas aeruginosa strains, along with a gyrA mutation (T83I) conferring fluoroquinolone resistance.
Associations between antimicrobial use and the faecal resistome on broiler farms from nine European countries.
The study identified several antimicrobial resistance genes associated with antimicrobial use on broiler farms, including bla TEM, erm (B), tet (W), aadA cluster, cmx, and dfrA1.
Bloodstream and catheter-related infections due to different clones of multidrug-resistant and biofilm producer Corynebacterium striatum.
The study identified multiple AMR genes (ermX, aphA, cmx) and mutations in the gyrA gene associated with fluoroquinolone resistance in multidrug-resistant Corynebacterium striatum isolates.
Characterization of a SPM-1 metallo-beta-lactamase-producing Pseudomonas aeruginosa by comparative genomics and phenotypic analysis.
The study characterizes the multidrug-resistant Pseudomonas aeruginosa isolate CCBH4851, identifying several AMR genes including blaSPM-1, sul1, rmtD, blaOXA-56, aac(6')-I, aadA7, cmx, and bcr, as well as mutations in oprD and mexZ contributing to resistance.
Pan-Genome Analysis of Delftia tsuruhatensis Reveals Important Traits Concerning the Genetic Diversity, Pathogenicity, and Biotechnological Properties of the Species.
The study identifies multiple antimicrobial resistance genes in Delftia tsuruhatensis, including aminoglycoside, sulfonamide, trimethoprim, tetracycline, and phenicol resistance genes, indicating the potential for multidrug resistance in this species.
Carbendazim shapes microbiome and enhances resistome in the earthworm gut.
Carbendazim (CBD) increases the abundance and diversity of antibiotic resistance genes (ARGs) in the earthworm gut, particularly multidrug, glycopeptide, tetracycline, and sulfonamide resistance genes.
Evaluating the potential of third generation metagenomic sequencing for the detection of BRD pathogens and genetic determinants of antimicrobial resistance in chronically ill feedlot cattle.
The study identified various antimicrobial resistance genes (ARGs) in metagenomic sequencing data from chronically ill feedlot cattle, including genes conferring resistance to beta-lactams, aminoglycosides, macrolides, phenicols, tetracyclines, and trimethoprim. Notably, tetH was the most frequently detected resistance gene, and several ARGs were found to be associated with integrative and conjugative elements (ICEs).
The resistomes of Mycobacteroides abscessus complex and their possible acquisition from horizontal gene transfer.
The study identifies numerous AMR genes in Mycobacteroides abscessus complex, highlighting the widespread presence of resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, glycopeptides, and others. Key findings include the detection of beta-lactamases like blaLAP-1 and blaTLA-2, 23S rRNA methyltransferases such as erm(33), erm(43), and erm(44), and various aminoglycoside modifying enzymes. Additionally, vancomycin resistance genes like vanA, vanB, and vanC were identified, along with efflux pump genes contributing to multidrug resistance.
The pan-genome of the emerging multidrug-resistant pathogen Corynebacterium striatum.
The study identifies 15 antimicrobial resistance genes in Corynebacterium striatum, including genes conferring resistance to aminoglycosides, tetracyclines, chloramphenicol, macrolides, lincosamides, streptogramins, sulfonamides, and cationic antiseptics. These genes are often located in genomic islands and mobile genetic elements, highlighting the role of horizontal gene transfer in the spread of multidrug resistance.
Antimicrobial Resistance and Genetic Diversity of Pseudomonas aeruginosa Strains Isolated from Equine and Other Veterinary Samples.
The study identified several AMR genes in Pseudomonas aeruginosa strains isolated from equine and other veterinary samples, including beta-lactamases, aminoglycoside modifying enzymes, quinolone resistance genes, sulfonamide resistance genes, phenicol resistance genes, tetracycline resistance genes, and efflux pumps. Additionally, genes conferring resistance to quaternary ammonium compounds were detected.
Multidrug-resistant toxigenic Corynebacterium diphtheriae sublineage 453 with two novel resistance genomic islands.
Two multidrug-resistant toxigenic Corynebacterium diphtheriae isolates were analyzed, revealing two novel resistance genomic islands carrying 12 resistance genes, including ermX, cmx, aph(3')-Ib, aph(6)-Id, aadA1, dfrA15, sul1, cmlA, cmlR, and tet(33). Additionally, mutations in rpoB and gyrA were associated with resistance to rifampicin and ciprofloxacin, respectively.
Genomic and phenotypic analysis of a novel clinical isolate of Corynebacterium pyruviciproducens.
The study identified several AMR genes in Corynebacterium pyruviciproducens strain WYJY-01, including ermX, aph(3')-Ia, aph(3″)-Ib, aph(6)-Id, and cmx, which confer resistance to macrolide, lincosamide, streptogramin, aminoglycoside, and phenicol antibiotics.
Infection by a multidrug-resistant Corynebacterium diphtheriae strain: prediction of virulence factors, CRISPR-Cas system analysis, and structural implications of mutations conferring rifampin resistance.
Contribution of the Mobilome to the Configuration of the Resistome of Corynebacterium striatum.
The study identified 20 antimicrobial resistance genes in Corynebacterium striatum, with ErmX being the most prevalent. These genes are mainly associated with plasmid sequence regions and class 1 integrons, highlighting the role of mobile genetic elements in the dissemination of resistance.
Prevalence, Virulence Genes, Drug Resistance and Genetic Evolution of Trueperella pyogenes in Small Ruminants in Western China.
The study identified eight resistance genes in Trueperella pyogenes isolates from small ruminants in western China, including ant(2")-Ia, ant(3")-Ia, cmlA1, cmx, erm(X), lnu(A), sul1, and tet(W). These genes conferred resistance to various antibiotics such as gentamicin, chloramphenicol, erythromycin, clindamycin, sulfisoxazole, and tetracycline.
Microbial spectrum and resistance of odontogenic abscesses - microbiological analysis using next generation sequencing.
The study identified multiple AMR genes in odontogenic abscesses using NGS, including genes conferring resistance to tetracyclines, macrolides, lincosamides, aminoglycosides, chloramphenicol, sulfonamides, penicillins, and others. Notably, Fusobacterium showed resistance to clindamycin.
Comparative genomics of Pseudomonas paraeruginosa.
The study identifies various AMR genes and mutations in Pseudomonas paraeruginosa, including carbapenemases like blaVIM-2, blaVIM-6, blaVIM-28, and blaKPC-2, as well as efflux pump genes (mexAB-oprM, mexCD-oprJ, etc.), and mutations in oprD, mexS, mexR, mexZ, lasR, mvfR, and vqsM that contribute to antibiotic resistance.
Population structure and antimicrobial resistance of Corynebacterium diphtheriae in Victoria, Australia.
The study identified multiple AMR genes and mutations in contemporary Corynebacterium diphtheriae isolates from Victoria, Australia, including pbp2m, erm(X), aph(3')-Ia, aph(6)-Id, aph(3'')-Ib, tet(W), tet(33), tet(O), cmx, sul1, dfrA15, and mutations in gyrA and rpoB. These genes and mutations confer resistance to various antimicrobials such as penicillin, erythromycin, gentamicin, tetracycline, chloramphenicol, sulfamethoxazole, trimethoprim, ciprofloxacin, and rifampicin.
Genomic and phenotypic diversity among taxonomically ambiguous clinical Corynebacterium isolates.
The study identified multiple AMR genes, including erm(X), tet(W), and aminoglycoside modifying enzymes, in various Corynebacterium species, highlighting extensive antimicrobial resistance in clinical isolates.
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