Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
transcriptional regulator
Overview
Evolution of Colistin Resistance in the Klebsiella pneumoniae Complex Follows Multiple Evolutionary Trajectories with Variable Effects on Fitness and Virulence Characteristics.
The study identifies multiple genetic mutations and insertions associated with colistin resistance in Klebsiella pneumoniae complex strains, including mutations in phoP, phoQ, crrAB, crrC, wzc, rho, and lptD, as well as insertions of IS5 and IS102 elements.
Drug efflux and lipid A modification by 4-L-aminoarabinose are key mechanisms of polymyxin B resistance in the sepsis pathogen Enterobacter bugandensis.
The study identifies crrC, kexD, arnBCADTEF, acrABTolC, phoPQ, and crrAB as key genes involved in polymyxin B resistance in Enterobacter bugandensis through mechanisms involving drug efflux and lipid A modification with 4-L-aminoarabinose.
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