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Browse GenescspA

cspA

surface lipoprotein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to cspA

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Validation StatusCandidate

Overview

Validation Method: mutant generation and serum sensitivity assays
Organisms: Borrelia burgdorferi
Papers: 1
Databases: Reslit

Papers1

1

CspA-mediated binding of human factor H inhibits complement deposition and confers serum resistance in Borrelia burgdorferi.

PMID 19451251 · 2009

CspA mediates serum resistance in Borrelia burgdorferi by binding human factor H, thereby inhibiting complement deposition.

Gene Information

Gene Name: cspA
Allele: cspA
Encodes: surface lipoprotein
Source Database: Reslit
Organisms Tested In: • Borrelia burgdorferi
Validation Method: mutant generation and serum sensitivity assays

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research