Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
drug transporter
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| G123E | - | - | Escherichia coli | Aminoglycoside | Reslit | Candidate |
Analysis of a complete library of putative drug transporter genes in Escherichia coli.
The study identified 20 genes in Escherichia coli that confer resistance to various antimicrobial agents, including novel drug resistance determinants such as yceE, yceL, yidY, ydgFE, yegO, cusA, and ybjYZ. Additionally, several previously known genes were found to have broader resistance spectra than previously reported.
Complete genome sequence and phenotype microarray analysis of Cronobacter sakazakii SP291: a persistent isolate cultured from a powdered infant formula production facility.
The study identified several AMR genes in Cronobacter sakazakii SP291, including tellurite resistance genes (terX, terW, terA, terB, terC, terD), heavy metal efflux genes (cusS, cusR, cusC, cusF, czcB, czcA, cusA, copG, pcoS, pcoB, pcoA), and oxidative stress resistance genes (yebA, yibP, hmp, grxB, grxC).
Effects of Copper Addition on Copper Resistance, Antibiotic Resistance Genes, and intl1 during Swine Manure Composting.
The study found that copper addition affected the abundance of copper resistance genes (CRGs) and antibiotic resistance genes (ARGs) during swine manure composting. Specifically, the absolute abundances of pcoA, tcrB, erm(A), erm(B), and intI1 decreased, while those of copA and cusA increased. The high concentration of copper slowed down the dissipation of CRGs, ARGs, and intI1 during composting.
Porcine commensal Escherichia coli: a reservoir for class 1 integrons associated with IS26.
The study identified 17 antimicrobial resistance genes (ARGs) in 103 class 1 integron-positive Escherichia coli strains from porcine feces, highlighting the prevalence of multidrug-resistant commensal E. coli in pigs and their potential role in the dissemination of resistance genes.
Characterization of an Environmental Multidrug-Resistant Acinetobacter seifertii and Comparative Genomic Analysis Reveals Co-occurrence of Antimicrobial Resistance and Metal Tolerance Determinants.
The study characterizes an environmental multidrug-resistant Acinetobacter seifertii isolate (SAb133) and identifies multiple antimicrobial resistance genes, metal tolerance genes, and virulence factors. Key findings include the presence of bla ADC–25, bla TEM, and various efflux pump genes, along with metal tolerance genes and virulence factors.
Comparative analysis of multidrug resistance plasmids and genetic background of CTX-M-producing Escherichia coli recovered from captive wild animals.
The study identifies multiple AMR genes and mutations in MDR E. coli strains from captive wild animals, highlighting the presence of CTX-M-8 and CTX-M-65 beta-lactamases, along with various other resistance mechanisms such as aminoglycoside, tetracycline, and fluoroquinolone resistance genes, as well as mutations in quinolone resistance-determining regions.
Identification of a Cluster of Extended-spectrum Beta-Lactamase-Producing Klebsiella pneumoniae Sequence Type 101 Isolated From Food and Humans.
The study identifies a cluster of extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae sequence type 101 isolated from food and humans, highlighting the potential role of food as a source of multidrug-resistant bacteria transmission to humans.
First Description of Various Bacteria Resistant to Heavy Metals and Antibiotics Isolated from Polluted Sites in Tunisia.
The study identified the presence of blaTEM, blaSHV, silE, cusA, and merA genes in environmental bacteria isolated from polluted sites in Tunisia, indicating resistance to antibiotics and heavy metals.
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