Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
D-serine, L- and D-alanine, and glycine transporter
Overview
Reslit |
| Candidate |
| - | - | Mycobacterium tuberculosis | Cycloserine | Reslit | Candidate |
| - | - | Mycobacterium tuberculosis | Cycloserine | Reslit | Candidate |
A point mutation in cycA partially contributes to the D-cycloserine resistance trait of Mycobacterium bovis BCG vaccine strains.
A point mutation in the cycA gene of Mycobacterium bovis BCG, resulting in a G122S amino acid substitution, partially contributes to D-cycloserine resistance. The mutation affects the transporter's function, reducing D-cycloserine uptake and contributing to resistance.
Characterization of Escherichia coli D-cycloserine transport and resistant mutants.
The study identifies cycA as a gene that confers resistance to d-cycloserine in Escherichia coli when grown in minimal medium, but not in complex or biologically relevant media. Additionally, mutations in dadA and pnp were found to increase DCS resistance.
Genomic analysis of Mycobacterium tuberculosis variant bovis strains isolated from bovine in the state of Mato Grosso, Brazil.
The study identified multiple AMR genes and mutations in Mycobacterium tuberculosis variant bovis strains from Mato Grosso, Brazil, including resistance to pyrazinamide, isoniazid, rifampicin, streptomycin, ethambutol, ethionamide, fluoroquinolones, kanamycin, capreomycin, paraminosalicylic acid, cycloserine, bedaquiline, linezolid, and delamanid.
Global pathogenomic analysis identifies known and candidate genetic antimicrobial resistance determinants in twelve species.
Two candidate AMR genes, cycA and frdD, were experimentally validated in E. coli BW25113, showing conditional resistance to ciprofloxacin and ampicillin, respectively.
No comments yet. Be the first to comment!
© 2026 ResLit. Data sourced from PubMed literature analysis.
Built for antimicrobial resistance research