Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
zinc tolerance
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| czcD | Reslit | 9 | - | Salmonella enterica +9 | United States, Azores archipelago, Alberta, China, Brazil, Danakil Depression, Afar Region, Ethiopia, Nîmes (France)|Québec (Canada), Malaysia, Mekong Delta, Vietnam | 2014, 2015, 2018, 2021, 2022, 2023, 2024, 2025 | KJ862079|KJ862112|KM516031|KM516054 |
| - |
| CzcD | Reslit | 1 | - | Acinetobacter baumannii | - | 2016 | NZ_CP008706.1 | - |
In-feed use of heavy metal micronutrients in U.S. swine production systems and its role in persistence of multidrug-resistant salmonellae.
The study identified the pcoA gene associated with copper tolerance and the czcD gene associated with zinc tolerance in Salmonella isolates from swine, feed, and barn floors.
Natural hot spots for gain of multiple resistances: arsenic and antibiotic resistances in heterotrophic, aerobic bacteria from marine hydrothermal vent fields.
The study identifies multiple antibiotic and heavy metal resistance genes in marine hydrothermal vent bacteria, highlighting the presence of plasmid-encoded resistance mechanisms and the coexistence of resistance to various metals and antibiotics.
Copper Resistance of the Emerging Pathogen Acinetobacter baumannii.
The study identifies several putative copper resistance genes in Acinetobacter baumannii, including ActP2/CopA1, CopA/CueO, CueR, CzcA, CzcB, CzcC, CzcD, PcoA, CopB, CopC, CopR/CusR, CopS/CusS, and ActP1/CopA2, which are involved in copper detoxification and efflux mechanisms.
Integrative Conjugative Element ICEHs1 Encodes for Antimicrobial Resistance and Metal Tolerance in Histophilus somni.
The study identifies the integrative conjugative element ICEHs1 in Histophilus somni, which carries the tetracycline resistance gene tet(H), the multidrug efflux pump gene ebrB, and metal tolerance genes mco, czcD, and acr3. The element is capable of horizontal transfer and contributes to increased antimicrobial and metal resistance in H. somni.
Heavy Metal Resistance in Salmonella Typhimurium and Its Association With Disinfectant and Antibiotic Resistance.
The study identified heavy metal resistance genes (HMRGs) such as czcD, pcoC, and cnrA in Salmonella Typhimurium isolates, which were associated with resistance to multiple antibiotics and disinfectants. These genes were found to be transferable via conjugation, indicating their potential to spread resistance.
Mucilaginibacter sp. Strain Metal(loid) and Antibiotic Resistance Isolated from Estuarine Soil Contaminated Mine Tailing from the Fundão Dam.
The study identifies multiple AMR genes in Mucilaginibacter sp. 21p, including genes for resistance to quinolones, aminoglycosides, beta-lactamases, sulfonamides, tetracyclines, daptomycin, arsenic, zinc, manganese, cobalt, and cadmium. These genes are part of efflux pumps and other resistance mechanisms, indicating the strain's adaptability to metal(loid) and antibiotic stressors in contaminated environments.
Shotgun Metagenomics-Guided Prediction Reveals the Metal Tolerance and Antibiotic Resistance of Microbes in Poly-Extreme Environments in the Danakil Depression, Afar Region.
The study identified numerous antibiotic resistance genes (ARGs) and metal resistance genes (MRGs) in the metagenomes of Lake Afdera and the Assale salt plain in the Danakil Depression. Key ARGs included beta-lactamases (ACC-1, OXA-58, OXA-363, OXA-212, NDM-17, OXA-134, ACT-29, LRA-19), efflux pumps (emrB, abeM, abeS, mgrA, adeJ, MexC, adeL, adeH), sulfonamide resistance genes (sul1, sul2), tetracycline resistance genes (tet39, tetX, tetK), and others. MRGs included copper resistance genes (copC, copD), cadmium resistance gene (cadD), mercury resistance gene (merA), chromate resistance genes (chrB, chrA), nickel-cobalt-cadmium resistance genes (nccA, nccB), cobalt-zinc-cadmium resistance gene (czcD), arsenic resistance gene (arsO), lead resistance gene (pbrA), and mercury resistance genes (merB, merR, MIR).
Deciphering pathogenicity and virulence of the first Staphylococcus debuckii isolate from diabetic foot osteomyelitis.
The study characterizes the first Staphylococcus debuckii isolate from diabetic foot osteomyelitis, identifying genes associated with virulence and resistance, including tetK, ebpS, qacA/qacR, czcD, norA, mdeA, and sdrM.
Genomic characterisation of nasal isolates of coagulase-negative Staphylococci from healthy medical students reveals novel Staphylococcal cassette chromosome mec elements.
The study identified novel Staphylococcal cassette chromosome mec (SCC mec ) elements in four methicillin-resistant coagulase-negative Staphylococci (CoNS) isolates from healthy medical students. The isolates harbored various antimicrobial resistance genes, including mecA, blaZ, mphC, msrA, tetK, fusC, fusF, qacA, qacB, qacC, norA, copB, arsC, cadC, cadD, copZ, copA, copR, and czcD, which conferred resistance to beta-lactams, macrolides, tetracyclines, fusidic acid, quaternary ammonium compounds, fluoroquinolones, and heavy metals.
Antibiotic resistance and pathogenicity of Shiga-toxin-producing Escherichia coli (STEC) and non-STEC isolated from goats in the Mekong Delta, Vietnam.
The study identified several antibiotic resistance genes, including blaampC, tetA, sulII, qnrA, aadA1, and czcD, in E. coli isolates from goats in the Mekong Delta, Vietnam. It also detected virulent genes such as stx1, stx2, eae, and hlyA.
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