Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
two-component system histidine kinase
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| E238D | - | two-component sensor histidine kinase DacS | Clostridioides difficile | vancomycin | Reference Gene CatalogReslit | Confirmed |
| V183A | - | two-component sensor histidine kinase DacS | Clostridioides difficile | vancomycin | Reference Gene CatalogReslit | Confirmed |
| V238M | - | - | Clostridioides difficile | vancomycin | Reslit | Candidate |
| L183P | - | - | Clostridioides difficile | vancomycin | Reslit | Candidate |
Identification of pathways to high-level vancomycin resistance in Clostridioides difficile that incur high fitness costs in key pathogenicity traits.
Research Article
mutations in dacS are associated with vancomycin resistance
Genetic determinants of resistance to antimicrobial therapeutics are rare in publicly available Clostridioides difficile genome sequences.
Research Article
dacS