dfr13

dihydrofolate reductase

Validation StatusCandidate

Overview

Validation Method: sequencing and biochemical analysis
Drug Classes: Trimethoprim
Organisms: Escherichia coli, Salmonella enterica serovar Choleraesuis
Geographic Location: South Africa
Papers: 1
Databases: Reslit

Papers1

New Gene Cassettes for Trimethoprim Resistance, dfr13, and Streptomycin-spectinomycin Resistance, aadA4, Inserted on a Class 1 Integron.

PMID 10639362 · 2000

The study identifies two new gene cassettes, dfr13 and aadA4, which confer resistance to trimethoprim and streptomycin-spectinomycin, respectively. These genes were characterized through sequencing and biochemical analysis.

Gene Information

Gene Name: dfr13
Allele: dfr13
Encodes: dihydrofolate reductase
Source Database: Reslit
Confers Resistance To: Trimethoprim
Organisms Tested In: • Escherichia coli
• Salmonella enterica serovar Choleraesuis
Geographic Location: South Africa
Validation Method: sequencing and biochemical analysis
Sequence Accession: Z50802

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dfr13

Gene Information