dfrA
dihydrofolate reductase
NCBI Pathogen Isolates
Bacterial genomes carrying this gene
NCBI Reference Gene Catalog
Known alleles and reference sequences
UniProt
Protein entries specific to dfrA
AMR Rules
Browse AMR rules for dfrA
Curation StatusNot Validated
Overview
- Drug Classes
- trimethoprim
- Organisms
- Escherichia coli, Klebsiella pneumoniae
- Papers
- 1
Papers1
1
Antimicrobial Resistance Mechanisms and Molecular Detection Techniques
PMID 11585788 · 2023The paper discusses molecular detection methods for antimicrobial resistance, focusing on genes like mecA and blaZ, which confer resistance to beta-lactam antibiotics in staphylococci.
Gene Information
- Gene Name
- dfrA
- Allele
- dfr
- Encodes
- dihydrofolate reductase
- Validation Method
- PCR and sequencing
Confers Resistance To
trimethoprim
Organisms Tested In
• Escherichia coli
• Klebsiella pneumoniae
Isolation Details
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