Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
trimethoprim-resistant dihydrofolate reductase DfrA10
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| DfrA10 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 11 | TRIMETHOPRIM, Trimethoprim | Escherichia coli +9 |
| Australia, Belgium, Global, United States|coastal wetlands, China, Poland, Pakistan|China|United States|United Kingdom|Canada|Australia|Spain|Denmark|UAE|Ethiopia|India|South Asia |
| 2003, 2004, 2017, 2019, 2020, 2022, 2023, 2024 |
| L06418.4 |
| AAA92749.1 |
| dfrA10 | Card DatabaseResFinder Database | 2 | TRIMETHOPRIM | Escherichia coli +1 | - | 1987 | L06418 | AHG97174.1 |
In34, a complex In5 family class 1 integron containing orf513 and dfrA10.
In34, a complex In5 family class 1 integron containing orf513 and dfrA10.
The study identifies and characterizes the class 1 integron In34, which contains multiple antibiotic resistance genes including aadB, dfrA10, aphA1, catA1, blaTEM, and sul1. These genes confer resistance to various antibiotics such as gentamicin, kanamycin, tobramycin, trimethoprim, chloramphenicol, ampicillin, and sulfamethoxazole.
In34, a complex In5 family class 1 integron containing orf513 and dfrA10.
In34, a complex In5 family class 1 integron containing orf513 and dfrA10.
Salmonella genomic island 1 multidrug resistance gene clusters in Salmonella enterica serovar Agona isolated in Belgium in 1992 to 2002.
The study identifies various multidrug resistance gene clusters in Salmonella enterica serovar Agona, including SGI1-A, SGI1-G, and several deletion variants. Key genes include floR, aadA2, pse-1, dfrA10, and orf513, which confer resistance to multiple antibiotics.
Antimicrobial Resistance in Bacteria: Mechanisms and Current Challenges
This paper characterizes several beta-lactamases, including TEM-1, SHV-1, CTX-M-15, and NDM-1, which confer resistance to various beta-lactam antibiotics. It also identifies erm(B) and mef(A) as mechanisms of macrolide, lincosamide, and streptogramin B resistance. Additionally, aadA1 and aac(6')-Ib are noted for aminoglycoside resistance, while catA1 and floR contribute to chloramphenicol resistance. The vanA gene is associated with glycopeptide resistance, and mcr-1 is linked to polymyxin resistance.
The region of the IncN plasmid R46 coding for resistance to beta-lactam antibiotics, streptomycin/spectinomycin and sulphonamides is closely related to antibiotic resistance segments found in IncW plasmids and in Tn21-like transposons.
Characterization of Four Multidrug Resistance Plasmids Captured from the Sediments of an Urban Coastal Wetland.
Four multidrug resistance plasmids were captured from the sediments of an urban coastal wetland. These plasmids carried various resistance genes, including beta-lactamases, tetracycline resistance genes, sulfonamide resistance genes, and others, conferring resistance to multiple antibiotics.
High Prevalence of Metallo-β-Lactamase-Producing Enterobacter cloacae From Three Tertiary Hospitals in China.
The study identified multiple metallo-beta-lactamase genes, including blaNDM-1, blaIMP-26, blaIMP-4, blaIMP-1, blaVIM-4, and blaKPC-2, as major contributors to carbapenem resistance in Enterobacter cloacae isolates from three hospitals in China.
Mechanisms Protecting Acinetobacter baumannii against Multiple Stresses Triggered by the Host Immune Response, Antibiotics and Outside-Host Environment.
This review discusses the mechanisms that protect Acinetobacter baumannii against multiple stresses, including those from the host immune response, antibiotics, and the outside environment. It highlights the role of surface glycoconjugates, outer membrane components, and various virulence factors in evading immune defenses and surviving adverse conditions.
In Vitro Assessment of Antimicrobial Activity of Phytobiotics Composition towards of Avian Pathogenic Escherichia coli (APEC) and Other E. coli Strains Isolated from Broiler Chickens.
The study identifies several AMR genes in E. coli strains, including aadA, strA/strB, aphA1, aphA2, tetA, tetB, sul1, sul2, sul3, dfrA1, dfrA10, dfrA12, floR, and blaSHV, which confer resistance to various antibiotics such as streptomycin, neomycin, tetracycline, sulfonamides, trimethoprim, chloramphenicol, and cephalosporins.
Combatting extensively drug-resistant Salmonella: a global perspective on outbreaks, impacts, and control strategies.
The paper discusses the emergence and global spread of extensively drug-resistant (XDR) Salmonella, highlighting the resistance mechanisms involving genes such as blaCTX-M-15, floR, cat1, cat2, strA, strB, aacC(3), aadA, ant(3")-Ia, aph(3)-IIa, tet(A), tet(B), tet(D), tet(G), tet(H), dfrA10, dhfrXII, sul1, sul2, sul3, mphA, and ermB.
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