Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
dihydrofolate reductase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| DfrA24 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 6 | Trimethoprim, TRIMETHOPRIM +1 | Escherichia coli +1 | Sweden, China | 2007, 2010, 2022 |
| AJ972619|AM403715 |
| CAI99385.1 |
| dfrA24 | Card DatabaseResFinder Database | 2 | TRIMETHOPRIM | Escherichia coli | - | 2007 | AJ972619 | CAI99385.1 |
Two new dfr genes in trimethoprim-resistant integron-negative Escherichia coli isolates.
Two new trimethoprim resistance genes, dfrA24 and dfrA26, were identified in integron-negative Escherichia coli isolates.
Two new dfr genes in trimethoprim-resistant integron-negative Escherichia coli isolates.
Two new dfr genes in trimethoprim-resistant integron-negative Escherichia coli isolates.
Two new dfr genes in trimethoprim-resistant integron-negative Escherichia coli isolates.
Two new dfr genes in trimethoprim-resistant integron-negative Escherichia coli isolates.
Molecular characterisation of trimethoprim resistance in Escherichia coli and Klebsiella pneumoniae during a two year intervention on trimethoprim use.
The study identified various dfr genes, including dfrA1, dfrA17, dfrA5, dfrA7, dfrA8, dfrA12, dfrA14, dfrA24, and dfrA26, as major contributors to trimethoprim resistance in E. coli and K. pneumoniae. The distribution of these genes remained largely unchanged during the intervention period.
Multidrug Resistance Genes Carried by a Novel Transposon Tn7376 and a Genomic Island Named MMGI-4 in a Pathogenic Morganella morganii Isolate.
The study identifies a novel transposon Tn7376 and a genomic island MMGI-4 in a multidrug-resistant Morganella morganii isolate, carrying multiple antimicrobial resistance genes including dfrA24, mph(A), aadA1, sul1, floR, catA2, cmlA1, aph(3')-Ia, aac(6')-Ib-cr, tet(A), tet(B), arr-3, blaTEM-1B, blaDHA-17, blaCARB-2, blaOXA-1, blaCTX-M-3, and fosA3.
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