Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
trimethoprim-resistant dihydrofolate reductase DfrA3
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| DfrA3 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 10 | TRIMETHOPRIM, Trimethoprim +1 | Plasmid pAZ1 +7 |
| Global, River Mahananda, West Bengal, India|River Mahananda, Atlantic Southwest Shelves Province|Antarctic Province|Indian South Subtropical Gyre, USA|United States|China|Sri Lanka|Germany|Greece, China, Portugal|Antarctic|South Shetland Islands|North Adriatic Sea|Bohai Sea|Adriatic Sea|Pacific Ocean|Baltic Sea |
| 2010, 2013, 2020, 2022, 2023 |
| J03306.1 |
| AAA25550.1 |
| dfrA3 | Card DatabaseResFinder Database | 2 | TRIMETHOPRIM | Plasmid pAZ1 | - | 1988 | J03306 | AAA25550.1 |
Molecular characterisation of trimethoprim resistance in Escherichia coli and Klebsiella pneumoniae during a two year intervention on trimethoprim use.
Molecular characterisation of trimethoprim resistance in Escherichia coli and Klebsiella pneumoniae during a two year intervention on trimethoprim use.
Molecular characterisation of trimethoprim resistance in Escherichia coli and Klebsiella pneumoniae during a two year intervention on trimethoprim use.
Antimicrobial Resistance in Bacteria: Mechanisms and Current Challenges
This paper characterizes several beta-lactamases, including TEM-1, SHV-1, CTX-M-15, and NDM-1, which confer resistance to various beta-lactam antibiotics. It also identifies erm(B) and mef(A) as mechanisms of macrolide, lincosamide, and streptogramin B resistance. Additionally, aadA1 and aac(6')-Ib are noted for aminoglycoside resistance, while catA1 and floR contribute to chloramphenicol resistance. The vanA gene is associated with glycopeptide resistance, and mcr-1 is linked to polymyxin resistance.
Diverse gene cassettes in class 1 integrons of facultative oligotrophic bacteria of River Mahananda,West Bengal, India.
The study identified diverse antibiotic-resistance gene cassettes in class 1 integrons of facultative oligotrophic bacteria from River Mahananda, including aadA1, aadA2, aadA4, aadA5, dfrA1, dfrA5, dfrA7, dfrA12, dfrA16, dfrA17, dfrA28, dfrA30, dfr-IIe, blaIMP-9, aacA4, aac-6′-Ib, oxa1, oxa10, and arr2.
Characterization of plasmid pAZ1 and the type III dihydrofolate reductase gene.
Global ocean resistome revealed: Exploring antibiotic resistance gene abundance and distribution in TARA Oceans samples.
The study identified 313 ARGs in the global ocean, including mcr-1, which confers resistance to colistin. The most frequent ARGs were Qac and TETB(60), associated with multidrug efflux pumps and tetracycline resistance, respectively.
Identification of Antimicrobial Resistance Determinants in Aeromonas veronii Strain MS-17-88 Recovered From Channel Catfish (Ictalurus punctatus).
The study identified multiple antimicrobial resistance genes in Aeromonas veronii strain MS-17-88, including beta-lactamase genes (imiS, ampS), phenicol resistance genes (floR, catB2, catB7, vat(F)), colistin resistance genes (mcr-3, mcr-7.1), tetracycline resistance genes (tet(34), tet(35), tet(E)), and a trimethoprim resistance gene (dfrA3).
Characteristics and Epidemiology of Extended-Spectrum β-Lactamase-Producing Multidrug-Resistant Klebsiella pneumoniae From Red Kangaroo, China.
The study identified multiple AMR genes in a multidrug-resistant Klebsiella pneumoniae isolate from a Red Kangaroo, including beta-lactamases (bla DHA–3, bla SHV–1, bla CTX–M–14, bla TEM–191, bla TEM–1, bla CTX–M–3), aminoglycoside resistance genes (aph(3″)-Ib, aph(6)-Id, aac(3)-IIa, aac(6′)-Ib-cr, aadA16, arr-3), quinolone resistance genes (qnrS1, qnrB2), macrolide resistance gene (mphA), sulfonamide resistance genes (sul3, sul1), dihydrofolate reductase (dfrA3, dfrA27), chloramphenicol resistance gene (floR), tetracycline resistance genes (tetG, tetR), and multidrug efflux pump (qacEΔ1).
Molluscs-A ticking microbial bomb.
The paper discusses the presence of antibiotic resistance genes (ARGs) in bivalve molluscs, highlighting the spread of resistance to various antibiotics such as colistin, beta-lactams, fluoroquinolones, and tetracyclines. It emphasizes the role of bivalve aquacultures in the dissemination of ARGs and the potential risks to human health through the food chain.
Complete genome sequence and comparative analysis of a Vibrio vulnificus strain isolated from a clinical patient.
No comments yet. Be the first to comment!
© 2026 ResLit. Data sourced from PubMed literature analysis.
Built for antimicrobial resistance research