Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
trimethoprim-resistant dihydrofolate reductase DfrA31
Overview
Identification of acquired antimicrobial resistance genes.
Research Article
The study presents ResFinder, a web-based tool for identifying acquired antimicrobial resistance genes in whole-genome data. It successfully identifies resistance genes with high accuracy and agrees with phenotypic testing. The tool detects various resistance genes across different bacterial species, including beta-lactamases, aminoglycoside modifying enzymes, tetracycline resistance genes, and others.
Population genomics of the food-borne pathogen Vibrio fluvialis reveals lineage associated pathogenicity-related genetic elements.
Research Article
The study identified 21 antimicrobial resistance genes in Vibrio fluvialis, with 19 of them predominantly present in VflPop2. The tetracycline resistance gene tet(35) was found in 95% of VflPop2 strains, highlighting its significance in the population. Additionally, the plasmid pBD146 was associated with resistance to trimethoprim-sulfamethoxazole, and the presence of dfr6 gene in pBD146 was linked to this resistance.
Genomic diversity and antimicrobial resistance of Vibrio cholerae isolates from Africa: a PulseNet Africa initiative using nanopore sequencing to enhance genomic surveillance.
Research Article
The study identified a high prevalence of trimethoprim resistance genes (dfrA1, dfrA15, dfrA31) and other resistance genes such as floR, strA, strB, varG, blaCARB-2, aadA1, aadA2, sul1, sul2, catB9, tet(C), tet(G), tet(59), qacEdelta, and blaCMY-4 in Vibrio cholerae isolates from Africa. Fluoroquinolone resistance mutations (gyrA_S83I and parC_S85L) and nitrofuran resistance mutations (nfsA_R169C and nfsB_Q5*) were also prevalent.
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