Home Browse Genes Browse Mutations Download Collaborators About

Browse AMR Genes

Explore antimicrobial resistance genes from the literature

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research

Home Browse Genes Browse Mutations Download Collaborators About

Browse GenesdfrA46

dfrA46

trimethoprim-resistant dihydrofolate reductase DfrA46

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to dfrA46

Browse AMR rules for dfrA46

Validation StatusConfirmed2+ DBs

Overview

Mechanism: Purine synthesis
Drug Classes: TRIMETHOPRIM
Organisms: Vibrio cholerae
Papers: 1
Databases: Card DatabaseReference Gene CatalogResFinder Database

Papers1

1

Presence of dfr6 gene cassette in superintegron of non-O1/non-O139 strain of Vibrio cholerae.

PMID 19704128 · 2009

Gene Information

Gene Name: dfrA46
Allele: DfrA46
Encodes: trimethoprim-resistant dihydrofolate reductase DfrA46
Source Database: Reference Gene Catalog
Mechanism: Purine synthesis
Confers Resistance To: TRIMETHOPRIM
Organisms Tested In: • Vibrio cholerae
Sequence Accession: FJ905898.1
Protein Accession: ACY06082.1
Notes: ARO:3004547

2

Presence of dfr6 gene cassette in superintegron of non-O1/non-O139 strain of Vibrio cholerae.

PMID 19704128 · 2009

Gene Information

Gene Name: dfrA46
Allele: DfrA46
Encodes: trimethoprim-resistant dihydrofolate reductase DfrA46
Source Database: ResFinder Database
Mechanism: Purine synthesis
Confers Resistance To: TRIMETHOPRIM
Organisms Tested In: • Vibrio cholerae
Sequence Accession: FJ905898.1
Protein Accession: ACY06082.1
Notes: ARO:3004547

3

Presence of dfr6 gene cassette in superintegron of non-O1/non-O139 strain of Vibrio cholerae.

PMID 19704128 · 2009

Gene Information

Gene Name: dfrA46
Allele: DfrA46
Encodes: trimethoprim-resistant dihydrofolate reductase DfrA46
Source Database: Card Database
Mechanism: Purine synthesis
Confers Resistance To: TRIMETHOPRIM
Organisms Tested In: • Vibrio cholerae
Sequence Accession: FJ905898.1
Protein Accession: ACY06082.1
Notes: ARO:3004547

Comments (0)

No comments yet. Be the first to comment!

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research