Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
trimethoprim-resistant dihydrofolate reductase DfrF
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| DfrF | Card DatabaseReference Gene CatalogReslit | 10 | TRIMETHOPRIM, Trimethoprim | Enterococcus faecalis +6 | wastewater treatment plants|Canada, Alberta, Canada, China|United States of America|United Kingdom|Canada|Spain|Netherlands|France|Germany|Denmark|Europe|North America, Europe, Canada|United Kingdom|Alberta, Japan |
| 1999, 2014, 2020, 2021, 2022, 2024 |
| AF028812.1 |
| AAD01868.1 |
| dfrF | Card Database | 1 | - | Enterococcus faecalis | - | - | AF028812.1 | AAD01868.1 |
Factors that cause trimethoprim resistance in Streptococcus pyogenes.
Factors that cause trimethoprim resistance in Streptococcus pyogenes.
Comparative genomics of multidrug-resistant Enterococcus spp. isolated from wastewater treatment plants.
The study identified several AMR genes in multidrug-resistant Enterococcus spp. isolated from wastewater treatment plants, including vancomycin resistance genes (vanA, vanM, vanG, vanC), macrolide resistance genes (ermB, msrC), tetracycline resistance genes (tetL), aminoglycoside resistance genes (aad(6'), aac(6')-Ie-aph(2")-Ia, ant(9')-Ia, aph(3')-IIIa, SAT-4, ant(6')-Ia), chloramphenicol resistance gene (cat), dihydrofolate reductase genes (dfrE, dfrF, dfrG), and lincosamide resistance genes (InuB, InuG).
Surveillance of Enterococcus spp. reveals distinct species and antimicrobial resistance diversity across a One-Health continuum.
The study identified several AMR genes in Enterococcus spp., including erm(B), tet(M), optrA, dfrE, lsa(A), aac(6')-Ib, eat(A), ant(6)-Ia, aph(3')-IIIa, sat4, tet(L), bcrB, bcrC, dfrF, and dfrG, which confer resistance to various antibiotics such as macrolides, tetracyclines, oxazolidinones, trimethoprim, and aminoglycosides.
Genomic and pathogenic investigations of Streptococcus suis serotype 7 population derived from a human patient and pigs.
The study identified several AMR genes in Streptococcus suis serotype 7 strains, including tetracycline resistance genes (tet(O), tet(M), tet(W)), macrolide/lincosamide/streptogramin resistance gene (erm(B)), aminoglycoside resistance genes (ant(6)-Ia, aph(3')-IIIa, aac(6')-Ie-aph(2'')-Ia), trimethoprim resistance gene (dfrF), and chloramphenicol resistance gene (cat-TC).
River Biofilms Microbiome and Resistome Responses to Wastewater Treatment Plant Effluents Containing Antibiotics.
The study identified various antibiotic resistance genes (ARGs) in river biofilms upstream and downstream of a wastewater treatment plant (WWTP), including qnrA, qnrS, mfsA, ermC, ermX, macB, mefA_10, cat, catB3, aadB, aph(3')-III, AAC(3)-Ib, bacA_1, blaPer-1, blaIMP, blaTEM, blaKPC, blaDHA, cblA, ermC, ermY, ermX, mdtL, cusF, copD, qacA, mecA, dfrF, arnA, sul1, sulA, vat(A), IS6100, ISS1N, Intl1, blaCTX-M, blaIMP, mefA_10, tolC, mdfF, acrA, dfrA27, aac(6')-IIa, vanA, intl3, and TTV. These genes were associated with resistance to various antibiotics such as fluoroquinolones, macrolides, chloramphenicol, aminoglycosides, beta-lactams, polymyxins, sulfonamides, and others. The study also found that the resistome composition varied between upstream and downstream sites, indicating the impact of WWTP effluents on the distribution of ARGs in river biofilms.
Exploring the mobilome and resistome of Enterococcus faecium in a One Health context across two continents.
The study identifies various AMR genes in Enterococcus faecium, including vanA, vanB, ermB, ermT, ermA, aad(6), aph(3')-IIIa, aac(6')-Ie-aph(2')-Ia, sat-4, tetM, tet(W/N/W), dfrG, dfrF, lnuB, optrA, and lsaE, which are associated with different habitats and geographic locations.
The effects of antibiotic exposures on the gut resistome during hematopoietic cell transplantation in children.
The study identified 372 unique antibiotic resistance genes (ARGs) in the gut microbiome of children undergoing hematopoietic cell transplantation, with tetracycline, beta-lactam, and fluoroquinolone resistance genes being the most prevalent. Anaerobic antibiotic exposures were associated with an increase in the acquisition of new ARGs and the relative abundance of ARGs in the gut resistome.
A single amplified genome catalog reveals the dynamics of mobilome and resistome in the human microbiome.
The study identifies numerous AMR genes in oral and fecal SAGs, highlighting the presence of resistance mechanisms such as efflux pumps, quinolone resistance proteins, dihydrofolate reductases, erythromycin ribosome methyltransferases, and aminoglycoside phosphotransferases.
Characterization of Dihydrofolate Reductase Genes from Trimethoprim-Susceptible and Trimethoprim-Resistant Strains of Enterococcus faecalis.
The study identifies two dihydrofolate reductase genes, dfrE and dfrF, responsible for high-level trimethoprim resistance in Enterococcus faecalis. dfrE is an intrinsic gene, while dfrF is an acquired gene that confers resistance when expressed in E. coli.
No comments yet. Be the first to comment!
© 2026 ResLit. Data sourced from PubMed literature analysis.
Built for antimicrobial resistance research