drrab

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ABC transporter

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to drrab

AMR Rules

Browse AMR rules for drrab

Validation StatusCandidate

Overview

Validation Method: efflux assays in E. coli and in vitro using inside-out membrane vesicles
Drug Classes: ethidium bromide
Organisms: Streptomyces peucetius, Escherichia coli
Papers: 1
Databases: Reslit

Papers1

The DrrAB efflux system of Streptomyces peucetius is a multidrug transporter of broad substrate specificity.

PMID 24634217 · 2014

The DrrAB efflux system of Streptomyces peucetius is a multidrug transporter capable of exporting doxorubicin, Hoechst 33342, and ethidium bromide, demonstrating broad substrate specificity.

Gene Information

Gene Name: drrab
Allele: drrAB
Encodes: ABC transporter
Source Database: Reslit
Confers Resistance To: ethidium bromide
Organisms Tested In: • Streptomyces peucetius
• Escherichia coli
Validation Method: efflux assays in E. coli and in vitro using inside-out membrane vesicles

The DrrAB efflux system of Streptomyces peucetius is a multidrug transporter of broad substrate specificity.

PMID 24634217 · 2014

The DrrAB efflux system of Streptomyces peucetius is a multidrug transporter capable of exporting doxorubicin, Hoechst 33342, and ethidium bromide, demonstrating broad substrate specificity.

Gene Information

Gene Name: drrab
Allele: drrAB
Encodes: multidrug transporter
Source Database: Reslit
Confers Resistance To: ethidium bromide
Organisms Tested In: • Streptomyces peucetius
• Escherichia coli
Validation Method: kinetic analysis of efflux in inside-out membrane vesicles and E. coli cells

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drrab

View on PubMed

ABC transporter

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to drrab

AMR Rules

Browse AMR rules for drrab

Validation StatusCandidate

Overview

Validation Method: efflux assays in E. coli and in vitro using inside-out membrane vesicles
Drug Classes: ethidium bromide
Organisms: Streptomyces peucetius, Escherichia coli
Papers: 1
Databases: Reslit

Papers1

The DrrAB efflux system of Streptomyces peucetius is a multidrug transporter of broad substrate specificity.

PMID 24634217 · 2014

The DrrAB efflux system of Streptomyces peucetius is a multidrug transporter capable of exporting doxorubicin, Hoechst 33342, and ethidium bromide, demonstrating broad substrate specificity.

Gene Information

Gene Name: drrab
Allele: drrAB
Encodes: ABC transporter
Source Database: Reslit
Confers Resistance To: ethidium bromide
Organisms Tested In: • Streptomyces peucetius
• Escherichia coli
Validation Method: efflux assays in E. coli and in vitro using inside-out membrane vesicles

The DrrAB efflux system of Streptomyces peucetius is a multidrug transporter of broad substrate specificity.

PMID 24634217 · 2014

The DrrAB efflux system of Streptomyces peucetius is a multidrug transporter capable of exporting doxorubicin, Hoechst 33342, and ethidium bromide, demonstrating broad substrate specificity.

Gene Information

Gene Name: drrab
Allele: drrAB
Encodes: multidrug transporter
Source Database: Reslit
Confers Resistance To: ethidium bromide
Organisms Tested In: • Streptomyces peucetius
• Escherichia coli
Validation Method: kinetic analysis of efflux in inside-out membrane vesicles and E. coli cells

Comments (0)

No comments yet. Be the first to comment!

drrab

Gene Information

Gene Information

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drrab

Gene Information

Gene Information