eefB

efflux pump

Validation StatusCandidate

Overview

Validation Method: quantitative real-time RT-PCR and expression analysis
Drug Classes: Cefepime, Ceftazidime, Chloramphenicol
Organisms: Klebsiella pneumoniae
Papers: 1
Databases: Reslit

Papers1

Role of the two component signal transduction system CpxAR in conferring cefepime and chloramphenicol resistance in Klebsiella pneumoniae NTUH-K2044.

PMID 22496764 · 2012

The CpxAR two-component system contributes to resistance against cefepime and chloramphenicol in Klebsiella pneumoniae NTUH-K2044 by modulating efflux pump expression and outer membrane protein profiles.

Gene Information

Gene Name: eefB
Allele: eefB
Encodes: efflux pump
Source Database: Reslit
Confers Resistance To: CefepimeCeftazidimeChloramphenicol
Organisms Tested In: • Klebsiella pneumoniae
Validation Method: quantitative real-time RT-PCR and expression analysis
Sequence Accession: BAH60994.1|YP_002917062.1

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eefB

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