efrB

ABC transporter

Validation StatusCandidate

Overview

Validation Method: cloning in E. coli + drug susceptibility tests
Drug Classes: norfloxacin, ciprofloxacin, doxycycline, acriflavine, 4',6-diamidino-2-phenylindole, tetraphenylphosphonium chloride, daunorubicin, doxorubicin
Organisms: Enterococcus faecalis, Escherichia coli
Papers: 1
Databases: Reslit

Papers1

EfrAB, an ABC multidrug efflux pump in Enterococcus faecalis.

PMID 14638474 · 2003

The study identifies and characterizes EfrAB, an ABC multidrug efflux pump in Enterococcus faecalis, which confers resistance to multiple antimicrobial agents.

Gene Information

Gene Name: efrB
Allele: efrB
Encodes: ABC transporter
Source Database: Reslit
Confers Resistance To: norfloxacinciprofloxacindoxycyclineacriflavine4',6-diamidino-2-phenylindoletetraphenylphosphonium chloridedaunorubicindoxorubicin
Organisms Tested In: • Enterococcus faecalis
• Escherichia coli
Validation Method: cloning in E. coli + drug susceptibility tests

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efrB

Gene Information