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embC

NCBI Pathogen Isolates
Bacterial genomes carrying this gene
NCBI Reference Gene Catalog
Known alleles and reference sequences
AMR Rules
Browse AMR rules for embC
Validation StatusCandidate

Overview

Papers
2
Mutations
6

Mutations

Protein ChangeNucleotide ChangeMechanismOrganismResistance ToDatabaseValidation Status
L251R--Mycobacterium tuberculosis
Ethambutol
ResFinder
Established
E187E--Mycobacterium tuberculosis
Ethambutol
ResFinder
Established
A244T--Mycobacterium tuberculosis
Ethambutol
ResFinder
Established
T270I--Mycobacterium tuberculosis
Ethambutol
ResFinder
Established
A254G--Mycobacterium tuberculosis
Ethambutol
ResFinder
Established
A247P--Mycobacterium tuberculosis
Ethambutol
ResFinder
Established
Papers2
1

Tuberculosis drug resistance mutation database.

PMID 19209951 · 2009

Mutation Information

embC: p.L251RembC: p.A244TembC: p.A254GembC: p.A247P
Protein Change
L251R, A244T, A254G, A247P
Organisms
Mycobacterium tuberculosis
Confers Resistance To
Ethambutol
Source Database
ResFinder
2

Evolution of high-level ethambutol-resistant tuberculosis through interacting mutations in decaprenylphosphoryl-β-D-arabinose biosynthetic and utilization pathway genes.

PMID 23995136 · 2013

Mutation Information

embC: p.E187EembC: p.T270I
Protein Change
E187E, T270I
Organisms
Mycobacterium tuberculosis
Confers Resistance To
Ethambutol
Source Database
ResFinder