erm tr

methylase

Validation StatusCandidate

Overview

Mechanism: methylation of 23S rRNA
Validation Method: PCR and phenotypic analysis
Drug Classes: Erythromycin
Organisms: Streptococcus pyogenes
Geographic Location: Mexico|USA
Papers: 1
Databases: Reslit

Papers1

Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains isolated from invasive and non-invasive infections from Mexico and the USA during 1999-2010.

PMID 22217469 · 2012

The study identified mef A, erm B, and erm TR as the primary genes responsible for erythromycin resistance in Streptococcus pyogenes isolates from Mexico and the USA. The M phenotype was linked to mef A, while the cMLS and iMLS phenotypes were associated with erm B and erm TR, respectively.

Gene Information

Gene Name: erm tr
Allele: erm TR
Encodes: methylase
Source Database: Reslit
Mechanism: methylation of 23S rRNA
Confers Resistance To: Erythromycin
Organisms Tested In: • Streptococcus pyogenes
Geographic Location: Mexico|USA
Validation Method: PCR and phenotypic analysis

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erm tr

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