Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(37)
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Erm(37) | Card DatabaseReference Gene CatalogResFinder Database | 4 | Clindamycin, Azithromycin, Erythromycin, Telithromycin, Clarithromycin, Macrolide antibiotic, Lincosamide antibiotic, Streptogramin b antibiotic, Streptogramin antibiotic, Streptogramin a antibiotic +1 more | Mycobacterium tuberculosis CCDC5180, Mycobacterium tuberculosis H37Rv | - | 1998, 2004 | CP002885.1 | AHJ55183.1 |
| erm37 | Reslit | 3 | Macrolides, Lincosamides | Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium pinnipedii | Italy | 2023 | PRJEB66335 | - |
Molecular basis of intrinsic macrolide resistance in the Mycobacterium tuberculosis complex.
Research Article
Molecular basis of intrinsic macrolide resistance in the Mycobacterium tuberculosis complex.
Research Article
Antimicrobial Resistance Mechanisms in Mycobacterium tuberculosis
Review
The paper discusses the molecular mechanisms of drug resistance in Mycobacterium tuberculosis, focusing on genes like pncA, rspA, erm37, tlyA, eis, BlaC, mfpA, IniBAC, EfP, and Tap, which are involved in resistance to pyrazinamide, macrolides, lincosamides, capreomycin, viomycin, kanamycin, β-lactams, fluoroquinolones, isoniazid, ethambutol, and multiple antibiotics.
Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents.
Research Article
The study identifies the erm37 gene as a determinant of macrolide resistance in Mycobacterium tuberculosis, and demonstrates that sequanamycins can overcome this resistance.
Genomics insights into a Mycobacterium pinnipedii isolate causing tuberculosis in a captive South American sea lion (Otaria flavescens) from Italy.
Research Article
The study identified intrinsic resistance genes erm-37 and aac(2')-Ic in a Mycobacterium pinnipedii isolate from a sea lion, conferring resistance to macrolides and aminoglycosides, respectively.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Research Article
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