erm(40)

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rRNA methylase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to erm(40)

AMR Rules

Browse AMR rules for erm(40)

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic target alteration
Validation Method: PCR and sequencing
Drug Classes: Macrolides, Clindamycin, Clarithromycin, Erythromycin, Telithromycin, Lincomycin, Macrolide antibiotic, Lincosamide antibiotic, Streptogramin antibiotic
Organisms: Mycobacterium mageritense, Mycolicibacterium mageritense
Papers: 1
Databases: Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Papers1

Intrinsic macrolide resistance in rapidly growing mycobacteria.

Research Article

PMID 17005837 · 2006

This study identifies erm genes in various rapidly growing mycobacteria species, demonstrating their role in intrinsic macrolide resistance.

Gene Information

Gene Name: erm(40)
Allele: Erm(40)
Encodes: rRNA methylase
Source Database: Reslit
Confers Resistance To: macrolides
Organisms Tested In: • Mycobacterium mageritense
Validation Method: PCR and sequencing
Sequence Accession: AY154657|AY487229|AY570506|DQ144638|DQ144639|DQ144640|AY570506|DQ144641|DQ144642|DQ447745|DQ144643|DQ435604|DQ435605

Intrinsic macrolide resistance in rapidly growing mycobacteria.

Research Article

PMID 17005837 · 2006

Gene Information

Gene Name: erm(40)
Allele: Erm(40)
Encodes: 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(40)
Source Database: Reference Gene Catalog
Mechanism: antibiotic target alteration
Confers Resistance To: CLINDAMYCINCLARITHROMYCINERYTHROMYCIN
Organisms Tested In: • Mycolicibacterium mageritense
Sequence Accession: AY570506.1
Protein Accession: AAS76623.1
Notes: ARO:3004606

Intrinsic macrolide resistance in rapidly growing mycobacteria.

Research Article

PMID 17005837 · 2006

Gene Information

Gene Name: erm(40)
Allele: Erm(40)
Encodes: 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(40)
Source Database: Card Database
Mechanism: antibiotic target alteration
Confers Resistance To: CLINDAMYCINCLARITHROMYCINERYTHROMYCIN
Organisms Tested In: • Mycolicibacterium mageritense
Sequence Accession: AY570506.1
Protein Accession: AAS76623.1
Notes: ARO:3004606

Intrinsic macrolide resistance in rapidly growing mycobacteria.

Research Article

PMID 17005837 · 2006

Gene Information

Gene Name: erm(40)
Allele: erm(40)
Source Database: ResFinder Database
Mechanism: Target modification
Confers Resistance To: TELITHROMYCINLINCOMYCINCLINDAMYCINERYTHROMYCIN
Organisms Tested In: • Mycolicibacterium mageritense
Sequence Accession: AY570506
Notes: 23S rRNA methylase; Natural in different Mycobacterium sp.

Intrinsic macrolide resistance in rapidly growing mycobacteria.

Research Article

PMID 17005837 · 2006

Gene Information

Gene Name: erm(40)
Allele: erm(40)
Encodes: Erm 23S ribosomal RNA methyltransferase
Source Database: Card Database
Mechanism: antibiotic target alteration
Confers Resistance To: MACROLIDE ANTIBIOTICLINCOSAMIDE ANTIBIOTICCLARITHROMYCINSTREPTOGRAMIN ANTIBIOTICERYTHROMYCINCLINDAMYCIN
Organisms Tested In: • Mycolicibacterium mageritense
Sequence Accession: AY570506.1
Protein Accession: AAS76623.1
Notes: ARO:3004606

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erm(40)

View on PubMed

rRNA methylase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to erm(40)

AMR Rules

Browse AMR rules for erm(40)

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic target alteration
Validation Method: PCR and sequencing
Drug Classes: Macrolides, Clindamycin, Clarithromycin, Erythromycin, Telithromycin, Lincomycin, Macrolide antibiotic, Lincosamide antibiotic, Streptogramin antibiotic
Organisms: Mycobacterium mageritense, Mycolicibacterium mageritense
Papers: 1
Databases: Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Papers1

Intrinsic macrolide resistance in rapidly growing mycobacteria.

Research Article

PMID 17005837 · 2006

This study identifies erm genes in various rapidly growing mycobacteria species, demonstrating their role in intrinsic macrolide resistance.

Gene Information

Gene Name: erm(40)
Allele: Erm(40)
Encodes: rRNA methylase
Source Database: Reslit
Confers Resistance To: macrolides
Organisms Tested In: • Mycobacterium mageritense
Validation Method: PCR and sequencing
Sequence Accession: AY154657|AY487229|AY570506|DQ144638|DQ144639|DQ144640|AY570506|DQ144641|DQ144642|DQ447745|DQ144643|DQ435604|DQ435605

Intrinsic macrolide resistance in rapidly growing mycobacteria.

Research Article

PMID 17005837 · 2006

Gene Information

Gene Name: erm(40)
Allele: Erm(40)
Encodes: 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(40)
Source Database: Reference Gene Catalog
Mechanism: antibiotic target alteration
Confers Resistance To: CLINDAMYCINCLARITHROMYCINERYTHROMYCIN
Organisms Tested In: • Mycolicibacterium mageritense
Sequence Accession: AY570506.1
Protein Accession: AAS76623.1
Notes: ARO:3004606

Intrinsic macrolide resistance in rapidly growing mycobacteria.

Research Article

PMID 17005837 · 2006

Gene Information

Gene Name: erm(40)
Allele: Erm(40)
Encodes: 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(40)
Source Database: Card Database
Mechanism: antibiotic target alteration
Confers Resistance To: CLINDAMYCINCLARITHROMYCINERYTHROMYCIN
Organisms Tested In: • Mycolicibacterium mageritense
Sequence Accession: AY570506.1
Protein Accession: AAS76623.1
Notes: ARO:3004606

Intrinsic macrolide resistance in rapidly growing mycobacteria.

Research Article

PMID 17005837 · 2006

Gene Information

Gene Name: erm(40)
Allele: erm(40)
Source Database: ResFinder Database
Mechanism: Target modification
Confers Resistance To: TELITHROMYCINLINCOMYCINCLINDAMYCINERYTHROMYCIN
Organisms Tested In: • Mycolicibacterium mageritense
Sequence Accession: AY570506
Notes: 23S rRNA methylase; Natural in different Mycobacterium sp.

Intrinsic macrolide resistance in rapidly growing mycobacteria.

Research Article

PMID 17005837 · 2006

Gene Information

Gene Name: erm(40)
Allele: erm(40)
Encodes: Erm 23S ribosomal RNA methyltransferase
Source Database: Card Database
Mechanism: antibiotic target alteration
Confers Resistance To: MACROLIDE ANTIBIOTICLINCOSAMIDE ANTIBIOTICCLARITHROMYCINSTREPTOGRAMIN ANTIBIOTICERYTHROMYCINCLINDAMYCIN
Organisms Tested In: • Mycolicibacterium mageritense
Sequence Accession: AY570506.1
Protein Accession: AAS76623.1
Notes: ARO:3004606

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erm(40)

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erm(40)

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