erm(52)

methyltransferase

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic target alteration
Validation Method: detection via SRST2 against ResFinder/ARGannot databases
Drug Classes: Macrolide, Lincosamide, Streptogramin b, MACROLIDE
Organisms: Clostridioides difficile
Geographic Location: Asia|Europe|North America|Australia/New Zealand
Papers: 1
Databases: Card DatabaseReference Gene CatalogReslit

Papers1

A species-wide genetic atlas of antimicrobial resistance in Clostridioides difficile.

PMID 34793295 · 2021

This study identifies multiple AMR genes and mutations in Clostridioides difficile, including ermB, tetM, mefH, and various mutations in gyrA, gyrB, rpoB, pbp1, and pbp3. These findings highlight the widespread nature of AMR in C. difficile and its potential role in the spread of the bacterium.

Gene Information

Gene Name: erm(52)
Allele: Erm(52)
Encodes: methyltransferase
Source Database: Reslit
Confers Resistance To: MacrolideLincosamideStreptogramin b
Organisms Tested In: • Clostridioides difficile
Geographic Location: Asia|Europe|North America|Australia/New Zealand
Validation Method: detection via SRST2 against ResFinder/ARGannot databases
Sequence Accession: BK013348

PMID N/A

Gene Information

Gene Name: erm(52)
Allele: Erm(52)
Encodes: 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(52)
Source Database: Reference Gene Catalog
Mechanism: antibiotic target alteration
Confers Resistance To: MACROLIDE
Organisms Tested In: • Clostridioides difficile
Sequence Accession: MW269959.1
Protein Accession: QQM99828.1
Notes: ARO:3007041

PMID N/A

Gene Information

Gene Name: erm(52)
Allele: Erm(52)
Encodes: 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(52), Erm 23S ribosomal RNA methyltransferase
Source Database: Card Database
Mechanism: antibiotic target alteration
Confers Resistance To: MACROLIDE
Organisms Tested In: • Clostridioides difficile
Sequence Accession: MW269959.1
Protein Accession: QQM99828.1
Notes: ARO:3007041

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erm(52)

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