Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
rRNA methylase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| ErmF | Card DatabaseReslit | 58 | Erythromycin, Clindamycin +7 |
| Seattle, Wash.|Montevideo, Uruguay|DeKalb County, Ga., human colon, Texas|Kenya, Japan, Minnesota, China, Denmark|Europe, Europe, Michigan, USA, UK, United States, Spain, Iran, Africa|Asia|Europe|North America|South America|global, California, Australia, Brazil, Norway, Shandong|Hebei|Jiangsu|Guangxi|Fujian|Henan|Guangdong, Bangladesh, Southern Germany|various, Shandong Province, China, India, Belgium, NSW, Australia, USA, Poland, Israel, Europe|Austria|Hungary |
| 1986, 1999, 2001, 2007, 2008, 2009, 2013, 2014, 2015, 2017, 2018, 2019, 2020, 2021, 2022, 2023, 2024, 2025 |
| X58717|Y08615|Z21523|M15332|X58285 |
| AAA88675.1 |
| Erm(F) | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 30 | STREPTOGRAMIN, CLINDAMYCIN +15 | Bacteroides thetaiotaomicron +55 | Denmark|United States|Ethiopia|England|Singapore|Asia|Belgium|Kenya|New Zealand, Global, India, Alberta, Denmark, Canada, Brazil, Minnesota, Shandong|Hebei|Jiangsu|Guangxi|Fujian|Henan|Guangdong, Shanxi Province, Belgium|Germany|Hungary|Slovenia|Turkey, Bulgaria, Europe, Australia | 1987, 1991, 2001, 2003, 2014, 2015, 2018, 2019, 2020, 2021, 2022, 2023, 2024, 2025, 2026 | AJ311171.1 | CAC47934.1 |
| erm(F) | ResFinder Database | 1 | QUINUPRISTIN, PRISTINAMYCIN IA +4 | Bacteroides fragilis | - | 1986 | M14730, M17808, M62487 | - |
| erm F | Reslit | 1 | Macrolide | Escherichia coli | Europe | 2021 | - | - |
Erythromycin-resistant Neisseria gonorrhoeae and oral commensal Neisseria spp. carry known rRNA methylase genes.
The study identifies the presence of known rRNA methylase genes (ermB, ermC, and ermF) in erythromycin-resistant Neisseria gonorrhoeae and oral commensal Neisseria spp., which confer resistance to erythromycin.
Evidence for extensive resistance gene transfer among Bacteroides spp. and among Bacteroides and other genera in the human colon.
The study shows extensive horizontal gene transfer of tetracycline resistance gene tetQ and erythromycin resistance genes ermF, ermG, and ermB among Bacteroides species and between Bacteroides and other genera in the human colon.
Characterization of the 13-kilobase ermF region of the Bacteroides conjugative transposon CTnDOT.
The study characterizes the ermF region in the Bacteroides conjugative transposon CTnDOT, identifying it as a source of resistance to erythromycin and clindamycin.
Characterization of the 13-kilobase ermF region of the Bacteroides conjugative transposon CTnDOT.
Acquired macrolide resistance genes in pathogenic Neisseria spp. isolated between 1940 and 1987.
The study identified the presence of acquired macrolide resistance genes erm(B), erm(C), erm(F), and mef(A) in Neisseria gonorrhoeae and Neisseria meningitidis isolates from 1940 to 1987. These genes were found in isolates dating back to 1955 and 1963, demonstrating the long-standing presence of these resistance mechanisms.
Bacteroides: the good, the bad, and the nitty-gritty.
The review discusses the role of Bacteroides species as commensals and pathogens, highlighting their complex relationships with the host, their resistance mechanisms, and their impact on health and disease.
Genetic tools for studying Capnocytophaga canimorsus.
The study describes the development of genetic tools for Capnocytophaga canimorsus, including the identification of functional resistance genes ermF, cfxA, and tetQ, which can be used as selection markers for plasmid maintenance in C. canimorsus and other Capnocytophaga species.
Nucleotide sequence of ermFU, a macrolide-lincosamide-streptogramin (MLS) resistance gene encoding an RNA methylase from the conjugal element of Bacteroides fragilis V503.
Nucleotide sequence of ermFU, a macrolide-lincosamide-streptogramin (MLS) resistance gene encoding an RNA methylase from the conjugal element of Bacteroides fragilis V503.
Antibiotic resistance genes in the vaginal microbiota of primates not normally exposed to antibiotics.
The study identified tetracycline resistance genes (tet(M), tet(W), tet(Q)) and erythromycin resistance genes (ermB, ermF) in the vaginal microbiota of primates not typically exposed to antibiotics, indicating the presence of antibiotic resistance genes in these animals despite limited antibiotic exposure.
Antimicrobial Resistance in Bacteria: Mechanisms and Current Challenges
This paper characterizes several beta-lactamases, including TEM-1, SHV-1, CTX-M-15, and NDM-1, which confer resistance to various beta-lactam antibiotics. It also identifies erm(B) and mef(A) as mechanisms of macrolide, lincosamide, and streptogramin B resistance. Additionally, aadA1 and aac(6')-Ib are noted for aminoglycoside resistance, while catA1 and floR contribute to chloramphenicol resistance. The vanA gene is associated with glycopeptide resistance, and mcr-1 is linked to polymyxin resistance.
PCR-based detection of resistance genes in anaerobic bacteria isolated from intra-abdominal infections.
The study identified several resistance genes, including cepA, cfiA, cfxA, tetQ, ermF, and mefA, in anaerobic bacteria isolated from intra-abdominal infections in Japan. A mutation in the gyrA gene was also found to confer resistance to fluoroquinolones.
Mechanisms of reduced susceptibility and genotypic prediction of antibiotic resistance in Prevotella isolated from cystic fibrosis (CF) and non-CF patients.
Role of peptidylarginine deiminase (PPAD) in the development of experimental periodontitis and arthritis
The study demonstrates that a PAD-deficient strain of Porphyromonas gingivalis was associated with reduced periodontal inflammation and decreased experimental arthritis severity in a mouse model.
Shotgun metagenomics reveals a wide array of antibiotic resistance genes and mobile elements in a polluted lake in India.
The study identified a diverse array of antibiotic resistance genes in a polluted lake in India, including sul2, qnrD, aph(6)-Id, aph(3′)-Ib, CMY2, qnrS, ant(3′)-Ia, dfrB1/dfrB5/dfrB6/dfrB8, GES, ere(A)/ere(C), qnrC, mph(E), dfrA1/dfrA15/dfrA25/dfrA30, erm(F), ant(2′)-Ia, cmlA, and tet(39). These genes conferred resistance to various classes of antibiotics, highlighting the significant presence of resistance mechanisms in the polluted environment.
Characterization of a multidrug-resistant, novel Bacteroides genomospecies.
Metronidazole- and Carbapenem-Resistant Bacteroides thetaiotaomicron Isolated in Rochester, Minnesota, in 2014.
The study identifies multiple antimicrobial resistance genes in a metronidazole- and carbapenem-resistant Bacteroides thetaiotaomicron isolate, including nimD, cat, tetX, tetQ, ermF, and a novel beta-lactamase gene.
ErmF and ereD are responsible for erythromycin resistance in Riemerella anatipestifer.
The study identifies ermF, ermFU, and ereD as the primary genes responsible for erythromycin resistance in Riemerella anatipestifer, demonstrating their role through cloning and MIC testing.
Sampling and Pooling Methods for Capturing Herd Level Antibiotic Resistance in Swine Feces using qPCR and CFU Approaches.
The study identified several antibiotic resistance genes in swine fecal samples using qPCR, including tetracycline resistance genes (tet(A), tet(B), tet(C), tet(M), tet(O), tet(W)), erythromycin resistance genes (ermB, ermF), sulfonamide resistance genes (sulI, sulII), beta-lactam resistance genes (blaCTX-M-1 group, blaCMY-2, blaSHV family), and glycopeptide resistance gene (vanA).
The prevalence of enterotoxin and antibiotic resistance genes in clinical and intestinal Bacteroides fragilis group isolates in Turkey.
The prevalence of enterotoxin and antibiotic resistance genes in clinical and intestinal Bacteroides fragilis group isolates in Turkey.
The prevalence of enterotoxin and antibiotic resistance genes in clinical and intestinal Bacteroides fragilis group isolates in Turkey.
Nucleotide sequence analysis of Tn4551: use of ermFS operon fusions to detect promoter activity in Bacteroides fragilis.
Nucleotide sequence analysis of Tn4551: use of ermFS operon fusions to detect promoter activity in Bacteroides fragilis.
Association between selected antimicrobial resistance genes and antimicrobial exposure in Danish pig farms.
The study identified several antimicrobial resistance (AMR) genes, including ermB, ermF, sulI, sulII, tet(M), tet(O), and tet(W), and examined their association with antimicrobial exposure in Danish pig farms. The results showed complex relationships between antimicrobial exposure and AMR gene levels, with varying correlations depending on the specific gene and antimicrobial class.
Comparison of antimicrobial resistance genes in feedlots and urban wastewater.
The study identified various antimicrobial resistance genes in feedlots and urban wastewater, highlighting the prevalence of sulfonamide, tetracycline, macrolide, fluoroquinolone, and β-lactam resistance genes in different environments.
Linking the Effect of Antibiotics on Partial-Nitritation Biofilters: Performance, Microbial Communities and Microbial Activities.
The study identified several genes associated with antibiotic resistance in a partial-nitritation biofilter exposed to a mixture of antibiotics. These included ermF, carA, and msrA for azithromycin resistance, gyrA and grlB mutations for norfloxacin resistance, and sul123 for sulfamethoxazole resistance.
Complete nucleotide sequence and transcription of ermF, a macrolide-lincosamide-streptogramin B resistance determinant from Bacteroides fragilis.
The study identifies ermF as a macrolide-lincosamide-streptogramin B resistance determinant in Bacteroides fragilis, encoding an rRNA methylase that confers resistance to macrolides, lincosamides, and streptogramin B.
Complete nucleotide sequence and transcription of ermF, a macrolide-lincosamide-streptogramin B resistance determinant from Bacteroides fragilis., Nucleotide sequence analysis of Tn4551: use of ermFS operon fusions to detect promoter activity in Bacteroides fragilis., Nucleotide sequence of ermFU, a macrolide-lincosamide-streptogramin (MLS) resistance gene encoding an RNA methylase from the conjugal element of Bacteroides fragilis V503.
Detection of critical antibiotic resistance genes through routine microbiome surveillance.
The study identifies various antibiotic resistance genes (ARGs) associated with multidrug resistance, including macrolide, beta-lactam, tetracycline, and methicillin resistance genes, highlighting the presence of these genes in postmortem microbiome samples.
Complete hybrid genome assembly of clinical multidrug-resistant Bacteroides fragilis isolates enables comprehensive identification of antimicrobial-resistance genes and plasmids.
The study identifies multiple antimicrobial resistance genes in multidrug-resistant Bacteroides fragilis isolates, including cfiA, nim, erm, tet, and others, using hybrid genome assembly and ABRicate screening.
Antimicrobial Resistance in Clostridium and Brachyspira spp. and Other Anaerobes.
The paper describes the antimicrobial resistance mechanisms in Clostridium and Brachyspira spp. and other anaerobes, focusing on the genetic basis of resistance to various antibiotics, including tetracyclines, macrolides, lincosamides, chloramphenicol, and others. It highlights the role of specific genes such as tet, erm, and cat in conferring resistance.
Metagenomic analysis reveals the microbiome and resistome in migratory birds.
The study identifies numerous antibiotic resistance genes (ARGs) in migratory birds, highlighting the presence of mcr-1, beta-lactamases, tetracycline resistance genes, and other resistance mechanisms. These findings suggest that migratory birds could serve as reservoirs and potential vectors for spreading ARGs into the environment.
Higher Prevalence of Multi-Antimicrobial Resistant Bacteroides spp. Strains Isolated at a Tertiary Teaching Hospital in China.
The study identifies the cfiA gene as the primary mechanism of carbapenem resistance in Bacteroides fragilis, along with other resistance genes such as cfxA, cepA, ermF, and nim. These genes contribute to resistance against various antibiotics including carbapenems, cefoxitin, clindamycin, and metronidazole.
Evolution of antibiotic resistance at low antibiotic concentrations including selection below the minimal selective concentration.
The study identifies ermF, intI1, and mphA as genes that show positive selection under specific antibiotic concentrations, highlighting their role in antibiotic resistance development at low concentrations.
Identification and characterization of invasive multi-drug-resistant (MDR) Bacteroides genomospecies in Canada.
The study identifies a novel multidrug-resistant Bacteroides genomospecies carrying the nimE gene associated with metronidazole resistance, along with other resistance genes such as tetQ, cfiA13, and erm(F).
Sewer biofilm microbiome and antibiotic resistance genes as function of pipe material, source of microbes, and disinfection: field and laboratory studies.
This study identified various antibiotic resistance genes (ARGs) in sewer biofilms, including sul1, blaTEM, tet(G), tet(O), tet(W), and ermF, which were detected in field and simulated sewer biofilm samples. The research also explored the effects of disinfection protocols on biofilm persistence.
Genomic Background and Phylogeny of cfiA-Positive Bacteroides fragilis Strains Resistant to Meropenem-EDTA.
The study identifies two new metallo-beta-lactamase genes, cfiA14b and cfiA28, in Bacteroides fragilis strains resistant to meropenem-EDTA. Additionally, various other AMR genes such as aadS, aac(3'), ermF, lnu(AN2), vatA, mef(En2), tetX, tetQ, cat, bexA, bexB, qacE, cusR, mexAB-oprM, mexJK-oprM, mexXY-oprM, acrEF-tolC, and mdtEF-tolC were characterized.
Antibiotic resistance pattern of Bacteroides fragilis isolated from clinical and colorectal specimens.
The study identified high resistance rates in Bacteroides fragilis isolates, particularly to penicillin G, tetracycline, clindamycin, and cefoxitin. Key resistance genes included tetQ, ermF, cepA, cfxA, and cfiA.
A Peek into the Plasmidome of Global Sewage
The study identifies several antimicrobial resistance (AMR) genes in plasmidomes from global sewage samples, highlighting the prevalence of macrolide, lincosamide, streptogramin B, and quinolone resistance genes on plasmids.
Metagenomic analysis of MWWTP effluent treated via solar photo-Fenton at neutral pH: Effects upon microbial community, priority pathogens, and antibiotic resistance genes.
Solar photo-Fenton treatment effectively removed a wide range of antibiotic resistance genes (ARGs) including those conferring resistance to sulfonamides, macrolides, tetracyclines, and beta-lactams. The study identified several ARGs such as sul1, sul2, tet(X), erm(F), mph(A), mph(E), msr(E), aadA, aph(3"), aph(6), strA, and blaBKC.
Danofloxacin Treatment Alters the Diversity and Resistome Profile of Gut Microbiota in Calves.
Danofloxacin treatment altered the gut microbiota diversity and resistome profile in calves, increasing the frequency and host range of several antimicrobial resistance genes (ARGs) such as aac(6')-Ib, ant9, tet40, tetW, ermF, tetL, and tetX.
Resistome Analysis in the Digestive Tract of Food-Producing Animals
The study identifies tetW and mefA as highly expressed tetracycline and macrolide resistance genes in the rumen of beef cattle, highlighting their significance in the resistome of food-producing animals.
Impact of Antibiotic Therapies on Resistance Genes Dynamic and Composition of the Animal Gut Microbiota.
The study examined the impact of antibiotic therapies on the dynamics and composition of resistance genes in the animal gut microbiota, identifying several AMR genes such as blaTEM, tetA, strA, strB, intI1, tetM, mel, floR, mcr-2, oqx B, tetC, tetG, tetO, tetW, tetX, ermB, ermF, sul1, sul2, and others, which were experimentally validated in Escherichia coli.
Quantification of antibiotic resistance genes and mobile genetic in dairy manure.
The study identified and quantified several antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) in dairy manure samples, highlighting the prevalence of sulII, tetW, ermF, tnpA, and intI1 across different manure management conditions.
The Evolutionary Trend and Genomic Features of an Emerging Lineage of Elizabethkingia anophelis Strains in Taiwan.
Genomic diversity and antimicrobial resistance of Prevotella species isolated from chronic lung disease airways.
The study identified ermF, tetQ, and cfxA as key AMR genes in Prevotella species, showing strong correlations with resistance to azithromycin, clindamycin, doxycycline, and ceftazidime. All isolates were resistant to tobramycin.
The impacts of viral infection and subsequent antimicrobials on the microbiome-resistome of growing pigs.
The study identified ermG as a gene that increased in abundance in the feces of treated pigs compared to those that did not receive post-PRRS antimicrobials, indicating its role in macrolide, lincosamide, and streptogramin B resistance.
Whole genome sequencing of the multidrug-resistant Chryseobacterium indologenes isolated from a patient in Brazil.
The study identified multiple antibiotic resistance genes and mutations in a multidrug-resistant Chryseobacterium indologenes strain, including beta-lactamases, quinolone resistance genes, tetracycline resistance genes, and efflux pumps, contributing to resistance against various antibiotics.
Exploring the Bacteriome and Resistome of Humans and Food-Producing Animals in Brazil.
The study identified various antimicrobial resistance genes (ARGs) in humans and food-producing animals in Brazil, including novel carbapenemase-encoding genes such as blaAIM-1, blaCAM-1, blaGIM-2, and blaHMB-1, which were not previously reported in Latin America. Other significant ARGs included aac(6')-Ib-cr, ermF, ermB, ermG, tetO, tetQ, tetW, qnrB10, qnrB19, qnrD1, and crpP.
Molecular Mechanisms of Drug Resistance and Epidemiology of Multidrug-Resistant Variants of Neisseria gonorrhoeae.
The paper discusses the development and evaluation of new antimicrobial agents against Neisseria gonorrhoeae, highlighting the importance of monitoring resistance mechanisms such as mutations in GyrA and ParC that confer resistance to fluoroquinolones.
A sludge bulking wastewater treatment plant with an oxidation ditch-denitrification filter in a cold region: bacterial community composition and antibiotic resistance genes.
The study identified several antibiotic resistance genes (ARGs) in a sludge bulking wastewater treatment plant, including sul1, aadA5, ErmF, tet(A), and msrE, which confer resistance to sulfonamide, aminoglycoside, macrolide, tetracycline, and other antibiotics.
Differential response to prolonged amoxicillin treatment: long-term resilience of the microbiome versus long-lasting perturbations in the gut resistome.
The study found that prolonged amoxicillin treatment leads to an increase in the abundance and diversity of antimicrobial resistance genes (ARGs) in the gut microbiome, particularly beta-lactamase genes such as cfxA and its variants, as well as tetracycline and macrolide resistance genes.
Antibiotic resistance of Riemerella anatipestifer and comparative analysis of antibiotic-resistance gene detection methods.
The study identified several antibiotic resistance genes in Riemerella anatipestifer, including OXA-209, erm(F), floR, aadS, tet(X), tet(X4), RanA, RanB, and ErmF, which confer resistance to various antibiotics such as beta-lactams, macrolides, fluoroquinolones, aminoglycosides, and tetracyclines.
Antibiotic resistance of Riemerella anatipestifer and comparative analysis of antibiotic-resistance gene detection methods.
The study identified several antibiotic resistance genes in Riemerella anatipestifer, including OXA-209, erm(F), floR, aadS, tet(X), tet(X4), RanA, RanB, and ErmF, which confer resistance to various antibiotics such as beta-lactams, macrolides, fluoroquinolones, aminoglycosides, and tetracyclines.
Antibiotic resistance of Riemerella anatipestifer and comparative analysis of antibiotic-resistance gene detection methods.
The study identified several antibiotic resistance genes in Riemerella anatipestifer, including OXA-209, erm(F), floR, aadS, tet(X), tet(X4), RanA, RanB, and ErmF, which confer resistance to various antibiotics such as beta-lactams, macrolides, fluoroquinolones, aminoglycosides, and tetracyclines.
Metagenomic analysis reveals patterns and hosts of antibiotic resistance in different pig farms.
The study identified various antibiotic resistance genes (ARGs) in pig manure samples from different regions of Shanxi, China, highlighting the prevalence of tetracycline, aminoglycoside, macrolide, and phenicol resistance genes. Key ARGs included tet(W), tet(40), tet(Q), erm(B), erm(F), mef(A), aph(3')-III, ant(6)-Ia, cfr(C), floR, blaACI-1, optrA, cat, cfxA4, cfxA5, blaCTX-M-105, blaCTX-M-65, fexB, erm(T), mdf(A), and ole(B).
Case Report: The effect of intravenous and oral antibiotics on the gut microbiome and breath volatile organic compounds over one year.
The study identified several resistance genes in Bacteroides coprophilus and Bacteroides dorei, including adeF, ermF, tetQ, ermG, and a carbapenem resistance gene, highlighting the impact of antimicrobial exposure on the gut microbiome's resistance profiles.
A multicentre study reveals dysbiosis in the microbial co-infection and antimicrobial resistance gene profile in the nasopharynx of COVID-19 patients.
The study identified a variety of antimicrobial resistance genes in the nasopharynx of COVID-19 patients, including beta-lactamases, macrolide-lincosamide-streptogramin resistance genes, tetracycline resistance genes, and others. These genes were found to be prevalent in both symptomatic and asymptomatic patients, highlighting the importance of monitoring antimicrobial resistance in the context of the pandemic.
The oral microbiota is a reservoir for antimicrobial resistance: resistome and phenotypic resistance characteristics of oral biofilm in health, caries, and periodontitis.
The study identified various antimicrobial resistance genes (ARGs) in the oral microbiota, including mefA, msrD, ermB, ermF, cfxA, blaCSP(1), tetM, tetQ, and pgpB, which confer resistance to antibiotics such as erythromycin, azithromycin, penicillin, ampicillin, tetracycline, and colistin. These genes were found in multiple bacterial species and were associated with different resistotypes in healthy, caries, and periodontitis groups.
Epidemiological investigation and drug resistance characteristics of Riemerella anatipestifer strains from large-scale duck farms in Shandong Province, China from March 2020 to March 2022.
The study identified multiple drug resistance genes in R. anatipestifer strains, including high prevalence of tetracycline resistance gene tet X (95.9%), macrolide resistance gene ermF (77%), and others. The strains exhibited multidrug resistance, with the highest resistance to gentamicin (77%) and enrofloxacin (73%).
Anaerobic Gram-Negative Bacteria: Role as a Reservoir of Antibiotic Resistance.
The study identifies several AMR genes in anaerobic Gram-negative bacteria, including nimE for metronidazole resistance, ermF for clindamycin resistance, cfiA for imipenem resistance, cepA for piperacillin-tazobactam resistance, and cfxA for cefoxitin resistance.
Cefquinome shows a higher impact on the pig gut microbiome and resistome compared to ceftiofur.
Cefquinome treatment led to a significant increase in several antimicrobial resistance genes, including tetQ, mel, ErmF, CfxA6, lsaB, and tet(40), whereas ceftiofur primarily increased tetQ and tet(40). The resistome returned to baseline levels within 21 days post-treatment.
Fecal antibiotic resistance genes were transferred through the distribution of soil-lettuce-snail food chain.
The study identified several antibiotic resistance genes (ARGs) such as aacA43, mel_1, vanRB, tetM, tnpA-2, sul1, sul2, ermF, and vatB that were transferred through the soil-lettuce-snail food chain. These genes conferred resistance to various antibiotics including aminoglycosides, tetracyclines, sulfonamides, MLSB, and vancomycin.
Baseline azithromycin resistance in the gut microbiota of preterm born infants.
The study identifies the presence of macrolide resistance genes in the gut microbiota of preterm infants, with erm(C) and msr(A) being the most common. These genes were found in various bacterial genera, including Staphylococcus and Enterococcus.
Cattle-compost-soil: The transfer of antibiotic resistance in livestock agriculture.
The study identifies a novel plasmid carrying the erythromycin resistance gene ermF, which confers resistance to erythromycin in Bacillus wiedmannii FSL W8-0169 and Escherichia coli DH5alpha.
Using 16S rDNA and metagenomic sequencing technology to analyze the fecal microbiome of children with avoidant/restrictive food intake disorder.
The study identified several antibiotic resistance genes in the fecal microbiome of children with ARFID, including vanT, tetQ, adeF, and ermF, with ermF showing significantly higher abundance in the ARFID group compared to healthy controls.
Altered microbiota, antimicrobial resistance genes, and functional enzyme profiles in the rumen of yak calves fed with milk replacer.
The study identified 138 antimicrobial resistance genes (ARGs) in the rumen of yak calves, with tetracycline resistance being the most prevalent. The study also found that feeding milk replacer (MR) altered the rumen resistome and microbiota, increasing the abundance of Prevotella and affecting the functional enzyme profiles.
The fate of antibiotic resistance genes during anaerobic digestion of sewage sludge with ultrasonic pretreatment.
The study investigated the effect of ultrasonic pretreatment on the fate of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) during anaerobic digestion of sewage sludge. It found that ultrasonic pretreatment significantly reduced the relative abundance of ARGs and MGEs, with 60 minutes of pretreatment achieving the highest removal rate of 41.70% for total ARGs.
Characterization of Riemerella anatipestifer Strains Isolated from Various Poultry Species in Poland.
The study identified several AMR genes in R. anatipestifer isolates, including aminoglycoside resistance genes (aph(3′)-VII, aac(3′)-IV, aadA, strA/strB), tetracycline resistance genes (tet(A), tet(B), tet(X)), erythromycin resistance gene (ermF), chloramphenicol resistance gene (cmlA), beta-lactam resistance gene (bla TEM), and sulfonamide resistance gene (sulI).
Effects of Neolamarckia cadamba leaves extract on microbial community and antibiotic resistance genes in cecal contents and feces of broilers challenged with lipopolysaccharides.
The study found that Neolamarckia cadamba leaves extract (NCLE) reduced the abundance of antibiotic resistance genes (ARGs) in cecal contents of lipopolysaccharide (LPS)-induced broilers by maintaining microbial balance.
Metagenomics reveals the temporal dynamics of the rumen resistome and microbiome in goat kids.
The study identified numerous antibiotic resistance genes (ARGs) in the rumen of goat kids, highlighting the dynamic nature of the resistome influenced by age and diet. Key ARGs included RPOB, GYRA, GYRBA, ROB, MDTF, ACRF, ACRB, MGTA, MLS23S, TUFAB, TET44, TET32, APH2-DPRIME, SAT, BRO, TETQ, ERMF, NIMJ, ACI, MEFA, RRSC, RRSH, CAP16S, TETX, LNUC, TETW, TETO, and TET40, which were associated with resistance to various antibiotics such as drugs, MLS, tetracyclines, and others.
Heterogeneous Antibiotic Resistance Gene Removal Impedes Evaluation of Constructed Wetlands for Effective Greywater Treatment.
The study identifies several antibiotic resistance genes (ARGs) in greywater and filter bed samples, including blaTEM, sul1, intI1, tetG, tetW, and others, indicating the presence of resistance to beta-lactams, sulfonamides, tetracyclines, and other antibiotics. The research highlights the variability in ARG removal efficiency by constructed wetlands and the potential for ARG proliferation in treated greywater.
Detection of the antibiotic resistance genes content of intestinal Bacteroides, Parabacteroides and Phocaeicola isolates from healthy and carbapenem-treated patients from European countries.
The study identified and compared the prevalence of antibiotic resistance genes in intestinal Bacteroides, Parabacteroides and Phocaeicola isolates from healthy and carbapenem-treated patients in European countries, highlighting differences in gene carriage between gut microbiota and clinical strains.
Metagenomic Investigation of the Short-Term Temporal and Spatial Dynamics of the Bacterial Microbiome and the Resistome Downstream of a Wastewater Treatment Plant in the Iskar River in Bulgaria.
The study identified various antimicrobial resistance genes (ARGs) in the Iskar River downstream of a wastewater treatment plant (WWTP), including genes conferring resistance to macrolides, tetracyclines, beta-lactams, sulfonamides, and carbapenems. Notably, the carbapenemase genes bla OXA-58 and bla IMP-33-like were detected, which are typically associated with clinical settings.
Deeper Exploration of Gut Microbiome: Profile of Resistome, Virome and Viral Auxiliary Metabolic Genes of Three Ethnic Indian Groups.
The study identified tetracycline resistance genes tet(W), erm(F), and tet(Q) in the gut microbiomes of three Indian ethnic groups, with higher burdens observed in the Khargone and Ladakh groups compared to the Jaisalmer group.
The role of New World vultures as carriers of environmental antimicrobial resistance.
The study identified several antimicrobial resistance genes (ARGs) in environmental samples collected from New World vultures, including blaTEM, sul1, ermA, ermF, tetA, and tetB, which confer resistance to beta-lactams, sulfonamides, macrolides, and tetracyclines. These genes were detected in Escherichia coli, enterococci, and Salmonella spp. across different sampling sites and seasons.
The characterization of outer membrane vesicles (OMVs) and their role in mediating antibiotic-resistance gene transfer through natural transformation in Riemerella anatipestifer.
Outer membrane vesicles (OMVs) from Riemerella anatipestifer strain CH-1 were shown to transfer antibiotic resistance genes (ARGs) and plasmids to the sensitive strain RA ATCC11845 through natural transformation, leading to increased resistance to erythromycin, tetracycline, and aztreonam.
Eradication of Helicobacter pylori reshapes gut microbiota and facilitates the evolution of antimicrobial resistance through gene transfer and genomic mutations in the gut.
H. pylori eradication led to the enrichment of various AMR genes, including beta-lactamases, macrolide phosphotransferases, erythromycin ribosome methyltransferases, sulfonamide resistance proteins, tetracycline efflux pumps, dihydrofolate reductase, quaternary ammonium compound efflux pumps, and aminoglycoside phosphotransferases. Additionally, genomic mutations in parC, parE, and gyrA were associated with fluoroquinolone resistance in E. coli.
Unveiling the silent threat: A comprehensive review of Riemerella anatipestifer - From pathogenesis to drug resistance.
This review highlights the pathogenesis, virulence factors, and antibiotic resistance genes of Riemerella anatipestifer, emphasizing its significance in poultry farming and the need for further research on its resistance mechanisms.
Potential pathogens drive ARGs enrichment during biofilms formation on environmental surfaces.
The study identifies several antibiotic resistance genes (ARGs) such as sul1, sul2, ermF, and intI-1 that are enriched in biofilms on environmental surfaces, highlighting the role of potential pathogens in ARG dissemination.
Presence of microplastic particles increased abundance of pathogens and antimicrobial resistance genes in microbial communities from the Oder river water and sediment.
The study identified several antimicrobial resistance (AMR) genes in microbial communities from the Oder river water and sediment, including blaTEM-116, erm(F), otr(C), ole(C), oqxB, dfrB3, tcr3, otr(A), vat(F), mph(E), srmB, and qepA4. These genes were associated with resistance to various antibiotics such as beta-lactams, macrolides, tetracyclines, and fluoroquinolones.
Potential pathogens and antimicrobial resistance genes in household environments: a study of soil floors and cow dung in rural Bangladesh.
The study identified multiple antimicrobial resistance genes (ARGs) in soil floors and cow dung samples from rural Bangladesh, including sul1, tet(Q), ermF, mexF, and cfxA2, which confer resistance to sulfonamides, tetracycline, macrolides, lincosamides, streptogramins, and cephalosporins.
Genomic analysis reveals two dominant strains of Ornithobacterium rhinotracheale in Austria and Hungary with distinct multidrug resistance profiles.
The study identifies distinct multidrug resistance profiles in two dominant strains of Ornithobacterium rhinotracheale from Austria and Hungary, highlighting the presence of resistance genes such as ermF, orr, tetX, and tetQ.
Natural Microbiota of Dogs and Cats as a Source and Vector of Resistance Genes-Clinical Significance.
The study identifies tetracycline resistance genes (tet(Q), tet(A)), macrolide resistance genes (mef(A), erm(B), erm(F)), and lincosamide resistance gene (lnu(C)) in the natural microbiota of dogs and cats, highlighting their potential as vectors for antimicrobial resistance.
Antimicrobial resistance is widespread among intestinal and extra-intestinal Bacteroides fragilis strains.
The study reveals that both intestinal and extra-intestinal B. fragilis strains possess comparable resistance gene profiles and antimicrobial susceptibility patterns, suggesting that intestinal strains serve as a reservoir of clinically relevant resistance determinants.
Temporal dynamics of the resistome in gilts raised in an organic operation in which semen used for artificial insemination is the primary source of antimicrobial exposure.
The study identified several tetracycline, aminoglycoside, and MLS resistance genes in the fecal microbiome of gilts, with no significant increases in ARG abundance following exposure to semen extenders containing antibiotics.
Cervicovaginal microbiome composition and absolute quantity are associated with pelvic inflammatory disease.
The study found that PID cases were associated with higher abundance of G. vaginalis and other CST IV organisms, while controls had higher levels of L. crispatus. No specific AMR genes were characterized in this paper.
Elucidation of population-based bacterial adaptation to antimicrobial treatment by single-cell sequencing analysis of the gut microbiome of a hospital patient.
The study identified 29 ARG subtypes across eight types in 13 known, five unknown, and 18 unclassified species, highlighting the complex and dynamic nature of antimicrobial resistance in the gut microbiome. Notably, the cfr(C) gene was detected in 11 bacterial species following antimicrobial treatment, with mutation patterns characterized in several species.
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