Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(T)
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Erm(T) | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 51 | STREPTOGRAMIN, TYLOSIN +15 |
| Taiwan, Germany|United Kingdom|Ireland|France|Malta|Abu Dhabi|Hong Kong|Australia|Trinidad & Tobago|United States|Italy|Spain|Portugal|Switzerland|Canada|Middle East|USA|Asia|UK, United States|USA, Global, Spain, Ireland, The Gambia, global|Europe|Belgium, Portugal, Bangladesh|Sweden, United Kingdom|Colombia, China, USA, Denmark, Hawai'i|Hawaiʻi Island, Netherlands, Germany, Minnesota, Henan|Hubei|Hunan|Anhui|Jiangxi|Shaanxi|Shanxi, Chiang Mai province, Northern Thailand|Thailand, France, Shanxi Province, Canada, Ghana, Norway, Slovak Republic, La Rioja, Spain, Vermont, South China, Europe, Sardinia, Italy |
| 1994, 2001, 2003, 2005, 2011, 2013, 2014, 2017, 2018, 2019, 2020, 2021, 2022, 2023, 2024, 2025 |
| AF310974.1 |
| AAG37071.1 |
| ErmT | Card DatabaseReslit | 30 | Erythromycin, Macrolide +5 | Streptococcus bovis +22 | Taiwan, France, Toronto, Ontario, Canada, China, United States, Canada, Africa|Asia|Europe|North America|South America|global, North America|Europe|International Space Station, Portugal, Canada|United Kingdom|Alberta, Spain, West Virginia, USA, Swiss Canton Tessin|various herds|Switzerland, Denmark, India, Latvia, Spain|Portugal|Germany|UK|Switzerland|Thailand|Italy, Canterbury, New Zealand, Europe|Africa|North America|South America|Asia|Oceania, Japan, Brazil | 2001, 2013, 2014, 2015, 2016, 2017, 2018, 2021, 2022, 2023, 2024, 2025 | CP007631|CP007632|SRP040805 | AAA98096.1 |
| ermT-02 | Reslit | 1 | Macrolide, Lincosamide +1 | - | Australia | 2020 | SRP201741 | - |
| erm(T) | ResFinder Database | 1 | QUINUPRISTIN, PRISTINAMYCIN IA +4 | Plasmid pGT633, Streptococcus pasteurianus, Lactobacillus sp. PC121B, Limosilactobacillus fermentum | - | 1994 | M64090, AY894138, AF310974, AJ488494 | - |
Sequence analyses of a broad host-range plasmid containing ermT from a tylosin-resistant Lactobacillus sp. Isolated from swine feces.
Sequence analyses of a broad host-range plasmid containing ermT from a tylosin-resistant Lactobacillus sp. Isolated from swine feces.
High prevalence of inducible erythromycin resistance among Streptococcus bovis isolates in Taiwan.
The study reports the high prevalence of inducible erythromycin resistance among Streptococcus bovis isolates in Taiwan, with the majority of resistant strains carrying the ermT or ermB gene.
Sequence and genetic organization of the 19.3-kb erythromycin- and dalfopristin-resistance plasmid pLME300 from Lactobacillus fermentum ROT1.
Sequence and genetic organization of the 19.3-kb erythromycin- and dalfopristin-resistance plasmid pLME300 from Lactobacillus fermentum ROT1.
The erm(T) gene is flanked by IS1216V in inducible erythromycin-resistant Streptococcus gallolyticus subsp. pasteurianus.
The study identifies the erm(T) gene, which confers inducible erythromycin resistance in Streptococcus gallolyticus subsp. pasteurianus, and shows that it is flanked by IS1216V elements.
The erm(T) gene is flanked by IS1216V in inducible erythromycin-resistant Streptococcus gallolyticus subsp. pasteurianus.
The erm(T) gene is flanked by IS1216V in inducible erythromycin-resistant Streptococcus gallolyticus subsp. pasteurianus.
A field guide to pandemic, epidemic and sporadic clones of methicillin-resistant Staphylococcus aureus.
The study characterizes various methicillin-resistant Staphylococcus aureus (MRSA) clones, highlighting their antimicrobial resistance and virulence-associated markers, with a focus on SCC mec types and PVL status.
The gut as reservoir of antibiotic resistance: microbial diversity of tetracycline resistance in mother and infant.
The study identified various tetracycline resistance genes, including tet(M), tet(L), erm(T), tet(W), tet(O), and tet(X), in the gut microbiota of a mother and her infant. It also discovered a novel composite transposon, Tn 6079, carrying tet(M), tet(L), and erm(T) in the infant's gut, highlighting the potential for horizontal gene transfer and maternal transmission of antibiotic resistance.
Antimicrobial Resistance in Bacteria: Mechanisms and Current Challenges
This paper characterizes several beta-lactamases, including TEM-1, SHV-1, CTX-M-15, and NDM-1, which confer resistance to various beta-lactam antibiotics. It also identifies erm(B) and mef(A) as mechanisms of macrolide, lincosamide, and streptogramin B resistance. Additionally, aadA1 and aac(6')-Ib are noted for aminoglycoside resistance, while catA1 and floR contribute to chloramphenicol resistance. The vanA gene is associated with glycopeptide resistance, and mcr-1 is linked to polymyxin resistance.
Novel erm(T)-carrying multiresistance plasmids from porcine and human isolates of methicillin-resistant Staphylococcus aureus ST398 that also harbor cadmium and copper resistance determinants.
The study identifies novel erm(T)-carrying multiresistance plasmids from porcine and human isolates of methicillin-resistant Staphylococcus aureus ST398, which also harbor cadmium and copper resistance determinants.
Clonal dynamics of nasal Staphylococcus aureus and Staphylococcus pseudintermedius in dog-owning household members. Detection of MSSA ST(398).
The study identified the presence of the MLS B resistance gene erm(T) and the cadmium resistance operon cadDX in MSSA ST398 isolates, highlighting their resistance mechanisms.
Clonal complex 398 methicillin susceptible Staphylococcus aureus: a frequent unspecialized human pathogen with specific phenotypic and genotypic characteristics.
The study identifies the ermT gene as a significant contributor to erythromycin resistance in CC398 MSSA strains, distinguishing them from CC398 LA-MRSA strains.
Methicillin-sensitive Staphylococcus aureus CC398 in intensive care unit, France.
The study identifies methicillin-sensitive Staphylococcus aureus clonal complex 398 (MSSA CC398) as a significant clone in an ICU setting in France, highlighting its resistance to erythromycin through the presence of the ermT gene.
A novel erythromycin resistance plasmid from Bacillus sp. strain HS24, isolated from the marine sponge Haliclona simulans.
The study identifies a novel 5.8 kb erythromycin resistance plasmid, pBHS24B, carrying the erm(T) gene, which confers erythromycin resistance in Bacillus sp. HS24 and Bacillus subtilis 168.
Population structure and antimicrobial resistance of invasive serotype IV group B Streptococcus, Toronto, Ontario, Canada.
The study identified ermTR and ermT genes associated with macrolide resistance, and tetM gene associated with tetracycline resistance in serotype IV group B Streptococcus strains.
Inducible Expression of both ermB and ermT Conferred High Macrolide Resistance in Streptococcus gallolyticus subsp. pasteurianus Isolates in China.
The study identifies that the inducible expression of both ermB and ermT genes confers high macrolide resistance in S. gallolyticus subsp. pasteurianus isolates from China.
Short-term increase in prevalence of nasopharyngeal carriage of macrolide-resistant Staphylococcus aureus following mass drug administration with azithromycin for trachoma control.
The study identified the presence of macrolide resistance genes msr, erm(C), and erm(T) in Staphylococcus aureus isolates following mass drug administration with azithromycin, contributing to increased prevalence of macrolide-resistant strains.
Bacteria from Animals as a Pool of Antimicrobial Resistance Genes.
The paper discusses the role of bacteria from animals as a reservoir of antimicrobial resistance genes, highlighting the presence of various AMR genes such as erm(B), tet(M), cfr, and others in different bacterial species, emphasizing their contribution to the spread of resistance.
Population and Whole Genome Sequence Based Characterization of Invasive Group A Streptococci Recovered in the United States during 2015.
The study identified several AMR genes and mutations in invasive group A streptococci, including ermT, ermB, ermTR, tetM, lsaC, mef, msrD, and mutations in ParC and GyrA that confer resistance to macrolides, tetracycline, and fluoroquinolones.
Prevalence and Genetic Basis of Antimicrobial Resistance in Non-aureus Staphylococci Isolated from Canadian Dairy Herds.
The study identified several AMR genes and mutations in non-aureus staphylococci from Canadian dairy herds, including blaZ, mecA, fexA, norA, sav1866, dha, mphC, msrA, tet38, tetK, tetL, tetM, folP, and mprF. Mutations in mprF and rpoC were associated with daptomycin resistance, while mutations in cls were not linked to resistance.
Increasing macrolide resistance among Streptococcus agalactiae causing invasive disease in non-pregnant adults was driven by a single capsular-transformed lineage, Portugal, 2009 to 2015.
The study identifies a significant increase in macrolide resistance among Streptococcus agalactiae isolates causing invasive disease in non-pregnant adults in Portugal, primarily linked to the expansion of a specific capsular-transformed lineage (CC1) harboring resistance genes such as erm(B), erm(TR), erm(T), mef(E), tet(M), tet(O), and tet(L).
The draft genomes and investigation of serotype distribution, antimicrobial resistance of group B Streptococcus strains isolated from urine in Suzhou, China.
The study identified several AMR genes in GBS isolates from urine in Suzhou, including tetM, ermB, mefE, lnuB, and others, associated with resistance to tetracycline, erythromycin, clindamycin, and fluoroquinolones.
Bifidobacterial Dominance of the Gut in Early Life and Acquisition of Antimicrobial Resistance.
High levels of Bifidobacterium in early life are associated with reduced levels of antimicrobial resistance (AMR) in the gut microbiome. Specifically, the gene ermX, encoding a 23S rRNA methyltransferase, was found to be significantly enriched in high-Bifidobacterium samples and is associated with resistance to macrolides, lincosamides, and streptogramin B.
High prevalence of spa type t571 among methicillin-susceptible Staphylococcus aureus from bacteremic patients in a French University Hospital.
The study identifies the ermT gene as the primary mechanism of erythromycin resistance in spa type t571 strains of methicillin-susceptible Staphylococcus aureus.
Severe Disseminated Infection with Emerging Lineage of Methicillin-Sensitive Staphylococcus aureus
The study reports a case of severe disseminated infection caused by methicillin-sensitive Staphylococcus aureus (MSSA) clonal complex 398, which exhibited resistance to penicillin, erythromycin, and clindamycin due to the presence of the blaZ and erm(T) genes.
Microbiological and clinical characteristics of Streptococcus gallolyticus subsp. pasteurianus infection in China.
The study characterizes the AMR genes and mutations in Streptococcus gallolyticus subsp. pasteurianus isolates from China, identifying erm(B), erm(A), erm(T), mef(A/E), tet(L), tet(O), and tet(M) as major contributors to erythromycin, clindamycin, and tetracycline resistance.
Manure Application Did Not Enrich Antibiotic Resistance Genes in Root Endophytic Bacterial Microbiota of Cherry Radish Plants.
The study found that manure application increased the occurrence of antibiotic resistance genes (ARGs) in the rhizosphere and phyllosphere of cherry radish, but not in the endophytic bacterial microbiota of the root, which is the edible part of the plant.
Unexpected relationships between frequency of antimicrobial resistance, disease phenotype and emm type in group A Streptococcus.
The study identifies specific AMR genes such as tet(M), erm(B), mef(A), msr(D), tet(O), erm(A), ant(6)-Ia, aph(3')-III, and erm(T) associated with resistance to tetracycline, erythromycin, clindamycin, and aminoglycosides in group A Streptococcus (GAS) strains. These genes are linked to high-frequency resistance in certain emm types, particularly emm11, emm75, emm77, and emm92, which are overrepresented in invasive GAS infections.
Antimicrobial Resistance and Virulence Gene Profiles of Methicillin-Resistant and -Susceptible Staphylococcus aureus From Food Products in Denmark.
The study identified several antimicrobial resistance genes, including blaZ, tet(K), tet(L), tet(M), and various erm genes, in Staphylococcus aureus isolates from food products in Denmark. Additionally, the tst gene was detected in CC398 and CC45 isolates, indicating the presence of toxic shock syndrome toxin.
In Vitro Pharmacodynamic Analyses Help Guide the Treatment of Multidrug-Resistant Enterococcus faecium and Carbapenem-Resistant Enterobacter cloacae Bacteremia in a Liver Transplant Patient.
The study identifies various AMR genes and mutations in Enterococcus faecium and Enterobacter hormaechei isolates from a liver transplant patient, highlighting their roles in resistance to multiple antibiotics.
Unusual accumulation of a wide array of antimicrobial resistance mechanisms in a patient with cytomegalovirus-associated hemophagocytic lymphohistiocytosis: a case report.
Effects of Low-Dose Antibiotics on Gut Immunity and Antibiotic Resistomes in Weaned Piglets.
The study identified two transferrable ARGs, Erm(T) and tcr3, which conferred resistance to macrolide and tetracycline, respectively, in weaned piglets exposed to low-dose antibiotics.
Effects of Low-Dose Antibiotics on Gut Immunity and Antibiotic Resistomes in Weaned Piglets.
The study identified two transferrable ARGs, Erm(T) and tcr3, which conferred resistance to macrolide and tetracycline, respectively, in weaned piglets exposed to low-dose antibiotics.
Evaluation of commercial probiotics for antimicrobial resistance genes.
The study found that 94% of the evaluated commercial probiotics contained at least one transferable antimicrobial resistance (AMR) gene, with 82% containing two or more. The most commonly detected AMR genes were tetK (68%) and sul2 (60%).
A Peek into the Plasmidome of Global Sewage
The study identifies several antimicrobial resistance (AMR) genes in plasmidomes from global sewage samples, highlighting the prevalence of macrolide, lincosamide, streptogramin B, and quinolone resistance genes on plasmids.
Environmental Surveillance and Characterization of Antibiotic Resistant Staphylococcus aureus at Coastal Beaches and Rivers on the Island of Hawai'i.
The study identified various antibiotic resistance genes in Staphylococcus aureus isolates from coastal beaches and rivers on the island of Hawai'i, highlighting the presence of multidrug-resistant strains.
Extensive Horizontal Gene Transfer within and between Species of Coagulase-Negative Staphylococcus.
The study identifies various antimicrobial resistance genes in CoNS species, including mecA, norA, vatB, vgaB, lsaB, erm(43), ermT, fusD, fusF, and salA, which confer resistance to beta-lactams, fluoroquinolones, lincosamides, macrolides, streptogramins, fusidic acid, and other antimicrobial agents. These genes are associated with horizontal gene transfer and recombination, highlighting the dynamic nature of CoNS evolution.
Misidentification of meticillin-resistant Staphylococcus aureus by the Cepheid Xpert MRSA NxG assay, the Netherlands, February to March 2021.
The study reports two false-negative results in detecting meticillin-resistant Staphylococcus aureus (MRSA) using the Cepheid Xpert MRSA NxG assay. The isolates were resistant to multiple antibiotics, including beta-lactams, aminoglycosides, and tetracyclines, and carried resistance genes such as blaZ, mecA, erm(T), aac(6')-aph(2"), tet(L), and tet(M).
Co-conjugation of Virulence Plasmid and KPC Plasmid in a Clinical Klebsiella pneumoniae Strain.
The study characterizes a carbapenem-resistant hypervirulent Klebsiella pneumoniae strain that harbors a conjugative virulence plasmid and a bla KPC–2-bearing plasmid. The virulence plasmid contains multiple resistance genes, including bla KPC–2, qnrB4, bla DHA–1, sul1, msr(E), mph(E), bla TEM–1B, aac(3)-IId, bla SHV–12, mph(A), bla CTX–M–65, bla TEM–1B, fosA3, and rmtB. The study also shows that these plasmids can be transferred to other bacterial strains, contributing to the spread of multidrug-resistant and hypervirulent K. pneumoniae.
Distribution and Clonal Diversity of Staphylococcus aureus and Other Staphylococci in Surface Waters: Detection of ST425-t742 and ST130-t843 mecC-Positive MRSA Strains.
The study identified mecC-positive MRSA strains ST425-t742 and ST130-t843 in surface waters, along with various AMR genes such as mecC, blaZ, ermT, msr(A/B), vgaA, tetL, mecA, mph(C), aac(6')-Ie-aph(2'')-Ia, aph(3')-IIIa, dfrA, fusB, and catpC221 in Staphylococcus aureus and coagulase-negative staphylococci.
erm(T)-Mediated Macrolide-Lincosamide Resistance in Streptococcus suis.
The study identified the erm(T) gene in two Streptococcus suis isolates, SC262-ST954 and SC117-ST1314, which conferred macrolide-lincosamide resistance. The gene was located on a plasmid and an ICE, and was transmissible to other bacteria like S. aureus and S. pneumoniae.
Antimicrobial and Biocide Resistance among Feline and Canine Staphylococcus aureus and Staphylococcus pseudintermedius Isolates from Diagnostic Submissions.
The study identified various antimicrobial resistance genes in feline and canine Staphylococcus aureus and Staphylococcus pseudintermedius isolates, including blaZ, mecA, mecC, tet(K), tet(M), erm(A), erm(B), erm(C), erm(T), msr(A), aadE, aacA-aphD, aphA3, aadD, dfrG, lnu(B), and lsa(E). These genes conferred resistance to multiple antibiotics such as penicillins, tetracyclines, macrolides, aminoglycosides, and others.
Antimicrobial Resistance and Clonal Lineages of Staphylococcus aureus from Cattle, Their Handlers, and Their Surroundings: A Cross-Sectional Study from the One Health Perspective.
The study identified various antimicrobial resistance genes in Staphylococcus aureus isolates from cattle, farm workers, and their environment, highlighting the potential for transmission between hosts and the need for monitoring AMR in One Health contexts.
The impacts of viral infection and subsequent antimicrobials on the microbiome-resistome of growing pigs.
The study identified ermG as a gene that increased in abundance in the feces of treated pigs compared to those that did not receive post-PRRS antimicrobials, indicating its role in macrolide, lincosamide, and streptogramin B resistance.
Genomic insight into the integrative conjugative elements from ICEHpa1 family.
The study identifies four novel ICEHpa1 variants (ICE Gpa1818, ICE Gpa1808, ICE Gpa1807, and ICE Gpa1815) carrying diverse resistance genes, including tetracycline, streptomycin, gentamicin, sulfamethoxazole/trimethoprim, florfenicol, and amoxicillin resistance genes.
Exploring the mobilome and resistome of Enterococcus faecium in a One Health context across two continents.
The study identifies various AMR genes in Enterococcus faecium, including vanA, vanB, ermB, ermT, ermA, aad(6), aph(3')-IIIa, aac(6')-Ie-aph(2')-Ia, sat-4, tetM, tet(W/N/W), dfrG, dfrF, lnuB, optrA, and lsaE, which are associated with different habitats and geographic locations.
The resistomes of Mycobacteroides abscessus complex and their possible acquisition from horizontal gene transfer.
The study identifies numerous AMR genes in Mycobacteroides abscessus complex, highlighting the widespread presence of resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, glycopeptides, and others. Key findings include the detection of beta-lactamases like blaLAP-1 and blaTLA-2, 23S rRNA methyltransferases such as erm(33), erm(43), and erm(44), and various aminoglycoside modifying enzymes. Additionally, vancomycin resistance genes like vanA, vanB, and vanC were identified, along with efflux pump genes contributing to multidrug resistance.
Genetic diversity and variation in antimicrobial-resistance determinants of non-serotype 2 Streptococcus suis isolates from healthy pigs.
The study identified 18 AMR genes in non-serotype 2 Streptococcus suis isolates from healthy pigs, including genes conferring resistance to aminoglycosides, macrolides, lincosamides, tetracyclines, oxazolidinones, nucleosides, and phenicols.
Web-based prediction of antimicrobial resistance in enterococcal clinical isolates by whole-genome sequencing.
The study evaluated the accuracy of whole-genome sequencing (WGS) for predicting antimicrobial resistance in enterococcal clinical isolates. It identified several AMR genes and mutations, including aac(6')-aph(2"), erm(B), erm(T), tet(L), tet(M), vanA, vanB, vanD, optrA, poxtA, and mutations in gyrA and parC, which were validated through genomic sequencing and phenotypic AST.
Metagenomic analysis reveals patterns and hosts of antibiotic resistance in different pig farms.
The study identified various antibiotic resistance genes (ARGs) in pig manure samples from different regions of Shanxi, China, highlighting the prevalence of tetracycline, aminoglycoside, macrolide, and phenicol resistance genes. Key ARGs included tet(W), tet(40), tet(Q), erm(B), erm(F), mef(A), aph(3')-III, ant(6)-Ia, cfr(C), floR, blaACI-1, optrA, cat, cfxA4, cfxA5, blaCTX-M-105, blaCTX-M-65, fexB, erm(T), mdf(A), and ole(B).
Staphylococcus aureus Carriage in the Nasotracheal Cavities of White Stork Nestlings (Ciconia ciconia) in Spain: Genetic Diversity, Resistomes and Virulence Factors.
The study identified several AMR genes in Staphylococcus aureus isolates from white stork nestlings, including blaZ, ermA, ermT, tetK, and lnuA, which confer resistance to penicillin, erythromycin, clindamycin, and tetracycline. Most isolates were methicillin-susceptible (MSSA) with low levels of AMR.
Emergence of Erythromycin-Resistant Invasive Group A Streptococcus, West Virginia, USA, 2020-2021.
The study identified the emergence of erythromycin-resistant invasive group A Streptococcus (iGAS) in West Virginia, with a high prevalence of resistance mediated by the ermT, ermA, ermB, and mefA genes. The majority of isolates were resistant to erythromycin and clindamycin, with emm92 and emm11 being the most common emm types.
Genomic Diversity of Methicillin-Resistant Staphylococcus aureus CC398 Isolates Collected from Diseased Swine in the German National Resistance Monitoring Program GERM-Vet from 2007 to 2019.
The study identified numerous antimicrobial resistance (AMR) genes in methicillin-resistant Staphylococcus aureus (MRSA) CC398 isolates from diseased swine in Germany, including beta-lactam, tetracycline, macrolide, lincosamide, streptogramin B, phenicol, aminoglycoside, and fluoroquinolone resistance genes. These genes were often located on small transposons or plasmids, contributing to the multidrug resistance profile of the isolates.
Pathogenicity and Antibiotic Resistance Diversity in Clostridium perfringens Isolates from Poultry Affected by Necrotic Enteritis in Canada.
The study identified several antimicrobial resistance genes in Clostridium perfringens isolates from poultry with necrotic enteritis, including tetA, tetB, tet44, InuP, erm(T), and ant(6)-Ib. The erm(T) gene was reported for the first time in C. perfringens and conferred resistance to erythromycin.
Elucidation of the Bovine Intramammary Bacteriome and Resistome from healthy cows of Swiss dairy farms in the Canton Tessin.
The study identified the presence of the tetracycline resistance gene tetK in Mammaliicoccus sciuri isolates, which was associated with tetracycline resistance. The gene was found on small plasmids, suggesting a potential mechanism for horizontal gene transfer.
The effects of antibiotic use on the dynamics of the microbiome and resistome in pigs.
The study identified several antibiotic resistance genes (ARGs) in porcine fecal microbiota, including aacA-aphD, ermT, lnuB, strB, sul2, tetA, tetM, and blaTEM, which showed increased abundance in antibiotic-treated pigs compared to untreated pigs.
An increase in erythromycin resistance in methicillin-susceptible Staphylococcus aureus from blood correlates with the use of macrolide/lincosamide/streptogramin antibiotics. EARS-Net Spain (2004-2020).
The study identifies erm(C), erm(A), erm(T), msr(A), and mph(C) as key genes contributing to erythromycin resistance in methicillin-susceptible Staphylococcus aureus (MSSA) isolates in Spain, with a notable increase in erm(T) prevalence post-2013.
Genomic insights into plasmid-mediated antimicrobial resistance in the bacterium Bhargavaea beijingensis strain PS04.
The study identified a novel plasmid-mediated antimicrobial resistance in Bhargavaea beijingensis strain PS04, carrying the ermT and tet(L) genes, which confer resistance to macrolides, lincosamides, streptogramin B, and tetracycline.
High Diversity but Monodominance of Multidrug-Resistant Bacteria in Immunocompromised Pediatric Patients with Acute Lymphoblastic Leukemia Developing GVHD Are Not Associated with Changes in Gut Mycobiome.
The study identifies multiple multidrug-resistant bacteria, including Enterococcus faecium and Klebsiella pneumoniae, carrying various resistance genes such as msr(C), erm(T), aac(6')-li, dfrG, ant(6)-la, aph(3")-Ib, sul2, and aph(6)-ld, which confer resistance to multiple antibiotics.
Enterococcus species: insights into antimicrobial resistance and whole-genome features of isolates recovered from livestock and raw meat in Ghana.
The study identified various antimicrobial resistance genes in Enterococcus spp. isolated from livestock and raw meat in Ghana, including genes conferring resistance to erythromycin, tetracycline, chloramphenicol, and other antibiotics. Notable genes include aac(6')-Ii, aph(3')-III, ant(6)-Ia, erm(B), erm(T), msr(C), lsa(A), lsa(E), lnu(B), tet(L), tet(M), tet(S), dfrG, cat, pbp5, and ClpL.
Clinical, microbiological, and molecular characterization of pediatric invasive infections by Streptococcus pyogenes in Spain in a context of global outbreak.
The study identified tetracycline resistance mediated by tetM, erythromycin and clindamycin resistance mediated by ermB, ermT, and mefA in Streptococcus pyogenes isolates from pediatric invasive infections in Spain.
Multidrug-resistant Enterococcus faecium strains enter the Norwegian marine environment through treated sewage.
The study identified multidrug-resistant Enterococcus faecium strains carrying resistance genes such as aac(6')-Ii, erm(B), erm(T), tet(L), tet(M), and msr(C), as well as mutations in gyrA and parC contributing to ciprofloxacin resistance.
Gut diversity and the resistome as biomarkers of febrile neutropenia outcome in paediatric oncology patients undergoing hematopoietic stem cell transplantation.
The study identifies several antibiotic-resistance genes associated with febrile neutropenia in pediatric oncology patients undergoing hematopoietic stem cell transplantation, including msr(C), dfrG, erm(T), VanHAX, aac(6')-Ib, aph(3')-III, ant(6)-Ia, and aac(6')-Ii.
Genetic Diversification and Resistome of Coagulase-Negative Staphylococci from Nostrils of Healthy Dogs and Dog-Owners in La Rioja, Spain.
The study identified various AMR genes including blaZ, mecA, erm(A), erm(C), erm(T), mph(C), msr(A), vga(A), lsaB, ant4′, aac6′-aph2″, tet(K), tet(M), dfrA, dfrG, catPC221, and mupA in CoNS isolates from healthy dogs and dog-owners. Additionally, a linezolid-resistant S. epidermidis isolate was found to have multiple amino acid substitutions in 50S ribosomal proteins L3 and L4.
Hybrid Illumina-Nanopore assembly improves identification of multilocus sequence types and antimicrobial resistance genes of Staphylococcus aureus isolated from Vermont dairy farms: comparison to Illumina-only and R9.4.1 nanopore-only assemblies.
The study identified various antimicrobial resistance genes in Staphylococcus aureus isolates from Vermont dairy farms, including beta-lactam resistance genes (blaZ, blaI, blaR), tetracycline resistance genes (tet(K), tet(38)), erythromycin resistance genes (erm(T), erm(A)), lincomycin resistance gene (lnu(G)), aminoglycoside resistance genes (aaC3, ant(9)-la), multidrug resistance efflux pumps (lmrS, mepA, mepR, mepB, norA, norB, arlS, arlR, mgrA), and fosfomycin resistance gene (fosB).
Evaluation of Antimicrobial Resistancein Clinical Isolates of Enterococcus spp. Obtained from Hospital Patients in Latvia.
The study identifies several AMR genes and mutations in Enterococcus isolates, including vanB for vancomycin resistance, lsaA, lsaE, lnuB for lincosamide resistance, tetM and tetL for tetracycline resistance, aac6'-Ii, aac6'-aph2'', aph3'-III, and ant6-Ia for aminoglycoside resistance, msrC, ermB, and ermT for macrolide resistance, and mutations in gyrA, parC, pbp5, and 23S rRNA for fluoroquinolone, penicillin, and linezolid resistance.
Antimicrobial Resistance in Coagulase-Negative Staphylococci: Resistome, Mobiloome, and Relatedness
The study identifies multiple AMR genes and mutations in CoNS isolates from various hosts, highlighting the spread of multidrug resistance and the role of mobile genetic elements in the dissemination of resistance traits.
Zoonotic transmission of asymptomatic carriage Staphylococcus aureus on dairy farms in Canterbury, New Zealand.
The study identified a bovine isolate carrying the extended-spectrum beta-lactamase gene blaTEM-116, highlighting concerns about antimicrobial resistance in dairy farm environments. Multiple antimicrobial resistance genes were detected in both bovine and human isolates, including genes conferring resistance to tetracyclines, penicillins, fosfomycin, and aminoglycosides.
Antibiotic Resistance in Mammalian Wild Game: A Meta-Analysis
The study presents a comprehensive meta-analysis of antibiotic resistance in bacteria isolated from mammalian wild game, highlighting the prevalence of various AMR genes and mutations across different bacterial species.
Detection of antimicrobial resistance in Glaesserella parasuis in South China using whole-genome sequencing.
The study identified several AMR genes and mutations in Glaesserella parasuis isolates from South China, including bla ROB–1, catA3, floR, erm(T), tet(B), and tet(H) for resistance to amoxicillin, chloramphenicol, florfenicol, erythromycin, and tetracycline, as well as mutations in gyrA, parC, and parE for enrofloxacin resistance.
Antimicrobial Susceptibility of Glaesserella parasuis to Macrolides and Characterization of erm(T)-Carrying Mobile Elements on Chromosome.
The study identified the macrolide resistance gene erm(T) and the A2059G mutation in 23S rRNA in Glaesserella parasuis. It also characterized ICEs carrying erm(T) for the first time in this species.
Antimicrobial Resistance in emm 89 Streptococcus pyogenes Strains from Japan
The study identified ermT, folP, lmrP, and group_31 as genes associated with antimicrobial resistance in emm 89 Streptococcus pyogenes strains from Japan.
Identification of Novel Staphylococcus aureus Core and Accessory Virulence Patterns in Chronic Rhinosinusitis.
The study identifies various antimicrobial resistance genes in Staphylococcus aureus isolates from patients with chronic rhinosinusitis, including blaI, blaZ, blaPC1, blaR1, erm(T), erm(A), tet(38), mepA, fosB, and ermC, which confer resistance to penicillin, macrolides, lincosamides, streptogramins, tetracycline, and fosfomycin.
Increase of macrolide resistance among Streptococcus pyogenes pharyngitis driven by a mef(A)-msr(D)/emm2-ST55 lineage in Portugal (2014-2019).
The study identifies the emergence of a mef(A)-msr(D) positive emm2-ST55 lineage as a major driver of increased macrolide resistance in Streptococcus pyogenes pharyngitis in Portugal between 2014 and 2019. It also characterizes various macrolide resistance genes including erm(A), erm(B), erm(T), tet(O), and tet(M) associated with different genetic lineages.
Emergence of Livestock-Associated Methicillin-Resistant Staphylococcus aureus ST398 in Wild Birds, Brazil.
The study reports the first detection of livestock-associated Methicillin-Resistant Staphylococcus aureus ST398 in wild birds in Brazil, highlighting the emergence of antimicrobial-resistant S. aureus in a protected Atlantic Forest fragment. The MRSA isolates exhibited a broad resistome, including genes for resistance to multiple antimicrobial classes.
Genomic characterization of Staphylococcus aureus isolated from mastitis in small ruminants in Sardinia, Italy.
The study identified erm(T), tet(K), and tet(M) as the primary AMR genes in S. aureus isolates from mastitis in Sardinia, with low resistance rates to erythromycin and tetracycline.
Molecular characterization of a plasmid-borne (pGT633) erythromycin resistance determinant (ermGT) from Lactobacillus reuteri 100-63.
Molecular characterization of a plasmid-borne (pGT633) erythromycin resistance determinant (ermGT) from Lactobacillus reuteri 100-63.
Molecular characterization of a plasmid-borne (pGT633) erythromycin resistance determinant (ermGT) from Lactobacillus reuteri 100-63.
Molecular characterization of a plasmid-borne (pGT633) erythromycin resistance determinant (ermGT) from Lactobacillus reuteri 100-63., The erm(T) gene is flanked by IS1216V in inducible erythromycin-resistant Streptococcus gallolyticus subsp. pasteurianus., Sequence analyses of a broad host-range plasmid containing ermT from a tylosin-resistant Lactobacillus sp. Isolated from swine feces., Sequence and genetic organization of the 19.3-kb erythromycin- and dalfopristin-resistance plasmid pLME300 from Lactobacillus fermentum ROT1.
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