erm(X)

ribosomal RNA methyltransferase

Validation StatusCandidate

Overview

Mechanism: methylation of 23S rRNA
Validation Method: cloning and MIC testing
Drug Classes: tylosin, erythromycin, spiramycin, clindamycin
Organisms: Arcanobacterium pyogenes
Papers: 1
Databases: Reslit

Papers1

Tylosin resistance in Arcanobacterium pyogenes is encoded by an erm X determinant.

PMID 14576111 · 2003

The study identifies erm(X) as a prevalent determinant of tylosin resistance in Arcanobacterium pyogenes, which confers resistance to macrolides, lincosamides, and streptogramin B antibiotics.

Gene Information

Gene Name: erm(X)
Allele: Erm(X)
Encodes: ribosomal RNA methyltransferase
Source Database: Reslit
Mechanism: methylation of 23S rRNA
Confers Resistance To: tylosinerythromycinspiramycinclindamycin
Organisms Tested In: • Arcanobacterium pyogenes
Validation Method: cloning and MIC testing
Sequence Accession: AY255627

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erm(X)

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