Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
methylase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| erm(Y) | ResFinder Database | 1 | QUINUPRISTIN, PRISTINAMYCIN IA +4 | Staphylococcus aureus | - | 2002 | AB014481 | - |
| Erm(Y) | Card Database |
| 5 |
| Macrolide, Lincosamide +9 |
| Staphylococcus aureus +1 |
| Global |
| 1998, 2002, 2023 |
| AB014481 |
| BAB20748.1 |
| ErmY | Card DatabaseReslit | 7 | Macrolide, Lincosamide +4 | Bacteroides ovatus ELH-B2 +5 | Europe, USA|Japan|Taiwan|NASA's-JPL SAF, Peninsular Malaysia|Malaysia | 2018, 2022, 2024, 2025 | NZ_CP012938 | BAB20748.1 |
New erm Gene in Staphylococcus aureus clinical isolates.
New erm Gene in Staphylococcus aureus clinical isolates.
The study identifies a novel erm gene, erm(Y), in Staphylococcus aureus clinical isolates, which confers resistance to macrolides, lincosamides, and streptogramin B through ribosomal modification.
Antimicrobial Resistance in Bacteria: Mechanisms and Current Challenges
This paper characterizes several beta-lactamases, including TEM-1, SHV-1, CTX-M-15, and NDM-1, which confer resistance to various beta-lactam antibiotics. It also identifies erm(B) and mef(A) as mechanisms of macrolide, lincosamide, and streptogramin B resistance. Additionally, aadA1 and aac(6')-Ib are noted for aminoglycoside resistance, while catA1 and floR contribute to chloramphenicol resistance. The vanA gene is associated with glycopeptide resistance, and mcr-1 is linked to polymyxin resistance.
Pilot Safety Evaluation of a Novel Strain of Bacteroides ovatus.
The study identified several antibiotic resistance genes in Bacteroides ovatus ELH-B2, including those conferring resistance to tetracycline, erythromycin, aminoglycosides, macrolides, and other antibiotics. These genes were validated through minimum inhibitory concentration (MIC) tests.
River Biofilms Microbiome and Resistome Responses to Wastewater Treatment Plant Effluents Containing Antibiotics.
The study identified various antibiotic resistance genes (ARGs) in river biofilms upstream and downstream of a wastewater treatment plant (WWTP), including qnrA, qnrS, mfsA, ermC, ermX, macB, mefA_10, cat, catB3, aadB, aph(3')-III, AAC(3)-Ib, bacA_1, blaPer-1, blaIMP, blaTEM, blaKPC, blaDHA, cblA, ermC, ermY, ermX, mdtL, cusF, copD, qacA, mecA, dfrF, arnA, sul1, sulA, vat(A), IS6100, ISS1N, Intl1, blaCTX-M, blaIMP, mefA_10, tolC, mdfF, acrA, dfrA27, aac(6')-IIa, vanA, intl3, and TTV. These genes were associated with resistance to various antibiotics such as fluoroquinolones, macrolides, chloramphenicol, aminoglycosides, beta-lactams, polymyxins, sulfonamides, and others. The study also found that the resistome composition varied between upstream and downstream sites, indicating the impact of WWTP effluents on the distribution of ARGs in river biofilms.
The resistomes of Mycobacteroides abscessus complex and their possible acquisition from horizontal gene transfer.
The study identifies numerous AMR genes in Mycobacteroides abscessus complex, highlighting the widespread presence of resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, glycopeptides, and others. Key findings include the detection of beta-lactamases like blaLAP-1 and blaTLA-2, 23S rRNA methyltransferases such as erm(33), erm(43), and erm(44), and various aminoglycoside modifying enzymes. Additionally, vancomycin resistance genes like vanA, vanB, and vanC were identified, along with efflux pump genes contributing to multidrug resistance.
Molecular Basis of Non-β-Lactam Antibiotics Resistance in Staphylococcus aureus.
The paper discusses the molecular mechanisms of resistance to non-beta-lactam antibiotics in Staphylococcus aureus, highlighting the roles of various genes and mutations in conferring resistance to macrolides, lincosamides, aminoglycosides, glycopeptides, oxazolidinones, lipopeptides, fluoroquinolones, and other antibiotics.
Novel spore-forming species exhibiting intrinsic resistance to third- and fourth-generation cephalosporins and description of Tigheibacillus jepli gen. nov., sp. nov.
The study identifies Tigheibacillus jepli as a novel spore-forming species with intrinsic resistance to third- and fourth-generation cephalosporins, lacking known β-lactamases, suggesting resistance via variant penicillin-binding proteins. It also reports three vancomycin resistance-related ARG in T. jepli.
Genomic Insights into Multidrug-resistant Mammaliicoccus sciuri Carrying Novel Staphylococcal Cassette Chromosome mec (SCCmec) Elements and Plasmids from Farm Ruminants on the East Coast of Peninsular Malaysia.
The study identified multiple antimicrobial resistance genes in four multidrug-resistant Mammaliicoccus sciuri isolates from farm ruminants in Peninsular Malaysia, including mecA, ermY, mphC, msrA, tetL, tetS, aadD, ant(6)-Ia, aac(6')-Ie-aph(2")-Ia, fexA, icaA, icaB, icaC, icaD, icaR, sspA, ndk, and lgt. These genes confer resistance to various antibiotics, including β-lactams, macrolides, tetracyclines, aminoglycosides, and chloramphenicol.
A plasmid that encodes three genes for resistance to macrolide antibiotics in Staphylococcus aureus.
A plasmid that encodes three genes for resistance to macrolide antibiotics in Staphylococcus aureus.
A plasmid that encodes three genes for resistance to macrolide antibiotics in Staphylococcus aureus.
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