ermsf

rRNA N-methyltransferase

Validation StatusCandidate

Overview

Validation Method: cloning and transfer to Streptomyces griseofuscus NRRL 23916
Drug Classes: Macrolide, Lincosamide, Streptogramin b
Organisms: Streptomyces fradiae, Streptomyces griseofuscus NRRL 23916
Papers: 1
Databases: Reslit

Papers1

Translational attenuation control of ermSF, an inducible resistance determinant encoding rRNA N-methyltransferase from Streptomyces fradiae.

PMID 3127381 · 1988

The ermSF gene from Streptomyces fradiae was identified as an inducible resistance determinant that confers resistance to macrolides, lincosamides, and streptogramin B antibiotics through rRNA N-methylation.

Gene Information

Gene Name: ermsf
Allele: ermSF
Encodes: rRNA N-methyltransferase
Source Database: Reslit
Confers Resistance To: MacrolideLincosamideStreptogramin b
Organisms Tested In: • Streptomyces fradiae
• Streptomyces griseofuscus NRRL 23916
Validation Method: cloning and transfer to Streptomyces griseofuscus NRRL 23916

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ermsf

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