exoS

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bifunctional enzyme with Rho-GAP and ADP-ribosyltransferase activities

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to exoS

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Validation StatusCandidate

Overview

Mechanism: confers resistance to antibiotics
Validation Method: presence in isolates and association with increased antibiotic resistance
Drug Classes: fluoroquinolones
Organisms: Pseudomonas aeruginosa
Geographic Location: South India
Papers: 1
Databases: Reslit

Papers1

Characterization of Ocular Clinical Isolates of Pseudomonas aeruginosa from Non-Contact Lens Related Keratitis Patients from South India.

PMID 32075262 · 2020

The study identified the presence of virulence genes such as exoU, exoS, lasB, aprA, prpL, and ladS in P. aeruginosa isolates from non-contact lens-related keratitis patients. These genes are associated with increased antibiotic resistance and virulence.

Gene Information

Gene Name: exoS
Allele: exoS
Encodes: bifunctional enzyme with Rho-GAP and ADP-ribosyltransferase activities
Source Database: Reslit
Mechanism: confers resistance to antibiotics
Confers Resistance To: fluoroquinolones
Organisms Tested In: • Pseudomonas aeruginosa
Geographic Location: South India
Validation Method: presence in isolates and association with increased antibiotic resistance

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exoS

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exoS

Gene Information