Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
enoyl-acyl carrier protein reductase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| fabV | Reslit | 2 | Triclosan | Pseudomonas aeruginosa PAO1 +3 | Brazil | 2010, 2024 | - | - |
| FabV | Reslit | 2 |
| Vibrio cholera +1 |
| - |
| 2018, 2021 |
| - |
| - |
Triclosan resistance of Pseudomonas aeruginosa PAO1 is due to FabV, a triclosan-resistant enoyl-acyl carrier protein reductase.
The study identifies FabV as the gene responsible for triclosan resistance in Pseudomonas aeruginosa PAO1. FabV encodes a triclosan-resistant enoyl-acyl carrier protein reductase, and its expression in E. coli conferred resistance to triclosan.
Distribution of triclosan-resistant genes in major pathogenic microorganisms revealed by metagenome and genome-wide analysis.
Dynamic Adaptive Response of Pseudomonas aeruginosa to Clindamycin/Rifampicin-Impregnated Catheters.
The study identified the upregulation of several antibiotic resistance proteins in P. aeruginosa PAO1 exposed to clindamycin/rifampicin-impregnated catheters, including porins, efflux pumps, and ribosomal proteins, indicating an adaptive response to antibiotic pressure.
The mobilome landscape of biocide-resistance in Brazilian ESKAPE isolates.
The study identified multiple biocide resistance genes in Brazilian ESKAPE isolates, highlighting the presence of resistance mechanisms against benzalkonium chloride, chlorhexidine, and triclosan. Key genes included efflux pumps (acrE/envC, acrF/envD, adeA, adeB, adeC, mexD, oqxA, oqxB, qacA, qacR, sdeB), enzyme modifiers (fabV, sh-fabI), and porins (kpnO).
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