fadl

long-chain fatty acid transporter

Validation StatusCandidate

Overview

Validation Method: transformation and sequencing
Drug Classes: a-344583
Organisms: Haemophilus influenzae
Papers: 1
Databases: Reslit

Papers1

Novel approach to mapping of resistance mutations in whole genomes by using restriction enzyme modulation of transformation efficiency.

PMID 15980348 · 2005

The study identified resistance mutations in the acrB gene, which encodes the B subunit of the AcrAB-TolC efflux pump, and in the fadL gene, which encodes a long-chain fatty acid transporter, for the antibacterial compounds A-84568 and A-344583, respectively.

Gene Information

Gene Name: fadl
Allele: fadL
Encodes: long-chain fatty acid transporter
Source Database: Reslit
Confers Resistance To: a-344583
Organisms Tested In: • Haemophilus influenzae
Validation Method: transformation and sequencing
Sequence Accession: HI1264|NP_439419|HI0567|NP_438724|HI0795|NP_438954

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fadl

Gene Information