fema
factor essential for methicillin resistance
NCBI Pathogen Isolates
Bacterial genomes carrying this gene
NCBI Reference Gene Catalog
Known alleles and reference sequences
UniProt
Protein entries specific to fema
AMR Rules
Browse AMR rules for fema
Validation StatusCandidate
Overview
- Mechanism
- mutations in femA lead to lysostaphin resistance
- Validation Method
- PCR amplification and nucleotide sequence analysis
- Organisms
- Staphylococcus aureus
- Papers
- 1
- Databases
- Reslit
Papers1
1
Mechanism and Suppression of Lysostaphin Resistance in Oxacillin-Resistant Staphylococcus aureus.
The study identifies mutations in the femA gene as the mechanism for lysostaphin resistance in oxacillin-resistant Staphylococcus aureus, and shows that coadministration of β-lactam antibiotics can suppress this resistance.
Gene Information
- Gene Name
- fema
- Allele
- femA
- Encodes
- factor essential for methicillin resistance
- Source Database
- Reslit
- Mechanism
- mutations in femA lead to lysostaphin resistance
- Organisms Tested In
- • Staphylococcus aureus
- Validation Method
- PCR amplification and nucleotide sequence analysis
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