flgE

flagellar hook protein

Validation StatusCandidate

Overview

Mechanism: biofilm formation and antibiotic tolerance
Validation Method: genomic knockout and biofilm tolerance assays
Drug Classes: Gentamicin, Colistin, Ciprofloxacin
Organisms: Pseudomonas aeruginosa
Papers: 1
Databases: Reslit

Papers1

Role of the flagellar hook in the structural development and antibiotic tolerance of Pseudomonas aeruginosa biofilms.

PMID 34880458 · 2022

The study identifies flgE as a gene that, when inactivated, leads to increased biofilm tolerance to gentamicin, colistin, and ciprofloxacin in Pseudomonas aeruginosa.

Gene Information

Gene Name: flgE
Allele: flgE
Encodes: flagellar hook protein
Source Database: Reslit
Mechanism: biofilm formation and antibiotic tolerance
Confers Resistance To: GentamicinColistinCiprofloxacin
Organisms Tested In: • Pseudomonas aeruginosa
Validation Method: genomic knockout and biofilm tolerance assays

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flgE

Gene Information