The study identifies multiple antibiotic resistance genes in the NDM-1-encoding Klebsiella pneumoniae strain, including eight beta-lactamase genes and various other resistance determinants, highlighting the complexity of its resistance profile.

The study developed a disk potentiation test to detect fosfomycin-nonsusceptible E. coli isolates producing glutathione S-transferases (FR-GSTs), specifically fosA3 and fosA4. The test involves the use of sodium phosphonoformate (PPF) to enhance the growth inhibition zone around fosfomycin disks, allowing reliable identification of FR-GST producers.

The study developed a disk potentiation test to detect fosfomycin-nonsusceptible E. coli isolates producing glutathione S-transferases (FR-GSTs), specifically fosA3 and fosA4. The test involves the use of sodium phosphonoformate (PPF) to enhance the growth inhibition zone around fosfomycin disks, allowing reliable identification of FR-GST producers.

The study reports the first occurrence of the fosfomycin resistance gene fosA3 and the carbapenemase gene blaKPC-2 coexisting on the same transposon, Tn1721, within a conjugative IncP plasmid in clinical Enterobacteriaceae isolates.

The paper discusses multidrug efflux pumps from various bacterial food pathogens including Enterobacteriaceae, Vibrio cholerae, and Staphylococcus aureus, highlighting their role in multidrug resistance.

The study identified fosA3 as a fosfomycin resistance gene in ESBL-producing E. coli isolates from humans and pigs in Taiwan. Additionally, mutations in murA, glpT, and uhpT were found to contribute to fosfomycin resistance.

The study reports the draft genome sequence of MDR Pseudomonas aeruginosa strain VRFPA09, identifying several AMR genes including blaVeb-1, blaOXA-10, aadA1, aph(3')Iib, Sul1, CatB7, TetG, dfrB5, and fosA, which contribute to resistance against various antibiotics.

The study identifies the fosA3 gene as the cause of high-level fosfomycin resistance in an E. coli strain from Pennsylvania, USA, and characterizes the plasmid carrying this gene.

The study identifies a novel plasmid pKP1034 carrying multiple resistance genes including fosA3, blaKPC-2, blaCTX-M-65, blaSHV-12, and rmtB in a Klebsiella pneumoniae ST11 strain, highlighting the complex resistance mechanisms and potential for horizontal gene transfer.

The paper discusses the mechanisms of resistance in carbapenem-resistant Enterobacteriaceae (CRE), focusing on beta-lactamases such as KPC, NDM, and OXA-48, as well as regulatory genes and efflux pumps contributing to polymyxin and tigecycline resistance.

The study identifies multiple antibiotic resistance genes, including oqxAB, bla CTX-M, aac(6')-Ib-cr, floR, qnrS1, rmtB, fosA3, pcoA, and silE, on ST3-IncHI2 plasmids from E. coli isolates of food-producing animals, highlighting the co-spreading of metal and antibiotic resistance.

The study identifies fosA6, a plasmid-mediated glutathione-S-transferase from Klebsiella pneumoniae that confers high-level fosfomycin resistance in ESBL-producing Escherichia coli. FosA6 functions as a GST and inactivates fosfomycin efficiently.

The study presents SSTAR, a software tool for identifying antimicrobial resistance (AR) genes from whole-genome sequencing data. It detects known AR genes and potential new variants, including truncated forms. The tool was applied to analyze resistance genes in Klebsiella pneumoniae ST437 and Escherichia coli ST44, revealing various beta-lactamases, aminoglycoside resistance genes, and porin mutations contributing to resistance.

The study presents a real-time analysis framework for MinION sequencing data, demonstrating the ability to identify pathogens and antibiotic resistance genes within a few hours of sequencing. Key resistance genes identified include blaSHV, mphA, strA, strB, blaTEM, sul2, blaOXA, aac3, aac6, blaCMY, blaCFE, blaLAT, blaBIL, QnrB, aadA, oqxA, tetA, oqxB, rmtC, sul1, sul3, fosA, blaNDM, oqxA, blaSHV, oqxB, aadB, sul1, sul3, blaOXA, blaOKP, fosA, blaSHV, blaOKP, blaLEN, oqxA, and oqxB.

The study identified numerous antimicrobial resistance genes in Escherichia coli isolates from river water, highlighting the presence of multidrug-resistant and extraintestinal pathogenic strains. Key resistance genes included blaTEM-1, aac(3)-IId, qnrB7, and others.

The paper discusses the mechanisms of fosfomycin resistance, including the identification of fosfomycin-modifying enzymes such as FosA, FosB, FosX, and FosA3, which inactivate fosfomycin and contribute to resistance in various bacterial species.

The paper discusses the mechanisms of fosfomycin resistance, including the identification of fosfomycin-modifying enzymes such as FosA, FosB, FosX, and FosA3, which inactivate fosfomycin and contribute to resistance in various bacterial species.

The study identified blaKPC-2 and blaNDM as the primary carbapenemase genes responsible for carbapenem resistance in CRE in China, with blaKPC-2 being more prevalent in K. pneumoniae and blaNDM in E. coli. Additionally, fosA3 was found to mediate fosfomycin resistance, and mcr-1 was associated with colistin resistance in some E. coli strains.

The study identified the emergence of plasmid-mediated fosfomycin-resistance genes, particularly fosA3 and fosA5, in Escherichia coli isolates in France, highlighting their association with extended-spectrum β-lactamase (ESBL) producers and potential implications for treatment failure.

The study identified the emergence of plasmid-mediated fosfomycin-resistance genes, particularly fosA3 and fosA5, in Escherichia coli isolates in France, highlighting their association with extended-spectrum β-lactamase (ESBL) producers and potential implications for treatment failure.

The study identified the emergence of plasmid-mediated fosfomycin-resistance genes, particularly fosA3 and fosA5, in Escherichia coli isolates in France, highlighting their association with extended-spectrum β-lactamase (ESBL) producers and potential implications for treatment failure.

The study identifies the widespread presence of the chromosomal fosA gene in various Gram-negative bacteria, which confers high-level fosfomycin resistance. The gene was shown to be responsible for fosfomycin resistance when expressed in E. coli and its deletion in S. marcescens eliminated resistance.

The study identified several AMR genes in Pseudomonas aeruginosa isolates, including blaADC35, aph(3')-II, blaOXA-50, catB7, and fosA, which conferred resistance to various antibiotics. The isolates showed varying resistance profiles, highlighting the complexity of AMR mechanisms in P. aeruginosa.

FosA3 and FosA_KP confer greater fosfomycin resistance than FosA_PA, primarily due to differences in their dimer interface loops and catalytic efficiency.

FosA3 and FosA_KP confer greater fosfomycin resistance than FosA_PA, primarily due to differences in their dimer interface loops and catalytic efficiency.

FosA3 and FosA_KP confer greater fosfomycin resistance than FosA_PA, primarily due to differences in their dimer interface loops and catalytic efficiency.

PPF inhibits FosA activity across Gram-negative species and can potentiate fosfomycin activity against the majority of strains with chromosomally encoded fosA.

The study demonstrates the feasibility of rapid nanopore sequencing for detecting plasmid-borne antimicrobial resistance (AMR) genes in clinical isolates. It identifies several AMR genes, including beta-lactamases, aminoglycoside-modifying enzymes, sulfonamide resistance genes, tetracycline resistance genes, macrolide resistance genes, and phenicol resistance genes, in both Escherichia coli and Klebsiella pneumoniae isolates.

The study identifies fosA3 as a plasmid-mediated fosfomycin resistance gene originating from the chromosome of Kluyvera georgiana. The gene was shown to confer high-level fosfomycin resistance when cloned in E. coli.

The study identified multiple antimicrobial resistance genes in 11 multidrug-resistant Klebsiella pneumoniae isolates, including ESBL genes (blaCTX-M-15, blaSHV-12, blaTEM-1B), fluoroquinolone resistance genes (oqxAB, qnrB), and others such as catA, catB, tet, sul, dfr, and fosA. These genes contribute to resistance against various antibiotics, highlighting the complex resistance profile of these isolates.

The study identified several AMR genes in Enterococcus faecalis and Enterobacter hormaechei isolated from neonatal feeding tubes, including lsaA (macrolide resistance), tetM (tetracycline resistance), blaACT-15 (beta-lactam resistance), and fosA (fosfomycin resistance).

The study identified a high prevalence of CTX-M-15-type ESBL-producing E. coli in migratory avian species in Pakistan, highlighting the role of wild birds as reservoirs of multidrug-resistant bacteria and the potential for horizontal gene transfer of resistance determinants.

The study identified multiple antibiotic resistance genes in ESBL-producing K. pneumoniae isolates from pigs and abattoir workers in Cameroon, including bla CTX-M-15, bla TEM-1B, bla SHV-28, and others, highlighting the presence of multidrug-resistant strains and their potential for zoonotic transmission.

The study identified the fosA gene as a determinant of fosfomycin resistance in E. coli, demonstrating its role in conferring resistance through experimental validation.

The study reports a pan-resistant Klebsiella pneumoniae isolate with resistance to all 26 antibiotics tested, including multiple beta-lactamases, aminoglycoside modifying enzymes, sulfonamide resistance, and colistin resistance due to mgrB inactivation.

The study identified 123 distinct antibiotic resistance genes (ARGs) in the genus Serratia, including intrinsic and acquired resistance genes, as well as efflux pump-related genes. Key findings include the detection of various beta-lactamases, aminoglycoside resistance genes, quinolone resistance genes, and efflux pumps. Notably, the study highlights the presence of plasmid-borne ARGs in nosocomial strains and the role of efflux pumps in multidrug resistance.

The study identifies multiple AMR genes and mutations in an XDR-KP strain, including blaKPC-3, blaOXA-9, blaTEM-1A, and various resistance mechanisms involving efflux pumps, porin deficiencies, and fluoroquinolone resistance mutations.

The study characterizes a novel multidrug resistance plasmid pSGB23 isolated from Salmonella enterica subspecies enterica serovar Saintpaul, carrying 11 antibiotic resistance genes responsible for resistance to 9 classes of antibiotics and quaternary ammonium compounds.

The paper discusses the characterization of various antimicrobial resistance genes in Escherichia coli, including extended-spectrum beta-lactamases (ESBLs), AmpC cephalosporinases, carbapenemases, plasmid-mediated quinolone resistance (PMQR) genes, aminoglycoside-modifying enzymes, fosfomycin resistance genes, and tetracycline resistance genes. These genes confer resistance to multiple classes of antibiotics, highlighting the complex nature of antimicrobial resistance in E. coli.

The study identifies novel and rare mutations in the arnT and eptA genes involved in lipid A modification pathways, along with novel fosA variants, contributing to colistin resistance in Klebsiella pneumoniae.

The study identifies novel and rare mutations in the arnT and eptA genes involved in lipid A modification pathways, along with novel fosA variants, contributing to colistin resistance in Klebsiella pneumoniae.

The study identifies novel and rare mutations in the arnT and eptA genes involved in lipid A modification pathways, along with novel fosA variants, contributing to colistin resistance in Klebsiella pneumoniae.

The study reports a fatal case of bacteremia caused by a hypermucoviscous KPC-2 producing extensively drug-resistant K64-ST11 Klebsiella pneumoniae. The isolate harbored multiple AMR genes including blaKPC-2, blaSHV-11, qnrS1, oqxA, oqxB, sul1, sul2, dfrA1, tetA, tetD, and fosA, contributing to its extensive drug resistance.

The study identified several AMR genes in Pseudomonas aeruginosa strains from different geographic locations, including beta-lactamases, aminoglycoside resistance genes, fosfomycin resistance, chloramphenicol resistance, sulfonamide resistance, quaternary ammonium compound resistance, tetracycline resistance, and others. Indian eye isolates exhibited a higher diversity of resistance genes compared to Australian isolates.

The study reports the draft genome sequence of a tigecycline-resistant Enterobacter cloacae ST93 clinical isolate, TREC1, which harbors multiple antimicrobial resistance genes, including those encoding resistance to beta-lactams, aminoglycosides, fluoroquinolones, fosfomycin, macrolides, lincosamides, streptogramin B, phenicols, sulfonamides, trimethoprim, and tetracyclines. The isolate is resistant to all antibiotics tested except colistin.

The study developed a rapid test for detecting fosfomycin resistance in E. coli, identifying fosA3 as a key gene responsible for acquired fosfomycin resistance.

The study identifies ANY1, a small-molecule inhibitor of FosA, which enhances fosfomycin activity against multidrug-resistant Gram-negative pathogens by inhibiting FosA-mediated fosfomycin metabolism.

The study identified multiple ESBL genes, including bla CTX-M-15, several bla SHV, bla TEM-63, and bla OXA-10, along with other AMR genes across diverse lineages of K. pneumoniae isolates from Malawi. No carbapenem resistance genes were detected, but plasmids similar to carbapenem resistance-associated plasmid pNDM-mar were found.

The study characterized multiple AMR genes in ESBL-producing K. pneumoniae isolates, including bla TEM-1B, bla CTX-M-15, bla SHV-1, bla OXA-1, aad AI6, aac (6′)Ib-cr, aph (6)Id, aph (3′)-Ib, oqx A, oqx B, fos A, ARR-3, sul 1, sul 2, dfr A14, dfr A27, cat A1, and cat B4.

The study characterizes the antimicrobial resistance genes and mutations in the emerging Klebsiella pneumoniae ST101 lineage, highlighting the presence of multiple resistance mechanisms including carbapenemases, extended-spectrum beta-lactamases, and various other resistance genes.

The study identifies a carbapenemase-producing hypervirulent Klebsiella pneumoniae isolate (CP-hvKP) in the United States, which carries the blaKPC-2 gene on a plasmid, along with other resistance genes such as blaSHV-36, fosA, oqxA, and oqxB. The isolate also possesses hypervirulence factors, highlighting the dual threat of antimicrobial resistance and virulence.

The study identified fosA and glpt genes associated with fosfomycin resistance in Pseudomonas aeruginosa isolates from Chinese mink, as well as mutations in gyrA and parC contributing to fluoroquinolone resistance.

The study identified various antimicrobial resistance (AMR) genes in commensal Escherichia coli isolates from children and domestic animals in a semirural community in Ecuador. These genes included blaTEM-1B, dfrA8, qnrB19, strA, strB, tetA, tetB, sul1, sul2, and others, contributing to resistance against multiple antibiotics such as ampicillin, trimethoprim, tetracycline, and sulfamethoxazole. The research highlights the role of plasmids in disseminating these AMR genes and emphasizes the complexity of AMR transmission in such environments.

The study evaluated the synergy of ceftazidime-avibactam (CZA) in combination with other antibiotics against multidrug-resistant Klebsiella pneumoniae and Pseudomonas aeruginosa. Several AMR genes, including blaKPC-2, blaKPC-3, blaCTX-M-15, and others, were identified as conferring resistance to CZA and other antibiotics.

The study identified various AMR genes and mutations in multidrug-resistant Klebsiella pneumoniae isolates, including bla KPC, bla CTX-M, bla TEM, and mutations in ompk35, ompk36, gyrA, and parC. These findings highlight the complex resistance mechanisms contributing to the persistence of MDR-Kp in the hospital setting.

The study identifies various AMR genes in ST258 K. pneumoniae isolates, including blaKPC-2, blaKPC-3, aadA2, aadA1, blaTEM-1A, blaSHV-11, blaSHV-12, oqxA, oqxB, fosA, dfrA12, dfrA14, sul1, sul2, catA1, cml, and strAB, which confer resistance to multiple antibiotics.

The study identifies the presence of blaKPC-2 and fosA3 on two novel hybrid plasmids in a multidrug-resistant porcine Klebsiella pneumoniae ST11 strain, highlighting the potential for transmission between animals and humans.

The study reports the in vivo transmission of the fosA9 gene from Klebsiella variicola to Escherichia coli, resulting in fosfomycin resistance.

The study characterizes a carbapenem-resistant Kluyvera cryocrescens isolate carrying blaNDM-1 on a self-transmissible IncX3 plasmid, along with other resistance genes such as blaSHV-12, blaCTX-M-3, qnrS1, sul1, fosA, dfrA21, and dfrA14.

The study identified various AMR genes, including bla OXA-23, bla OXA-66, bla NDM-1, bla NDM-5, bla NDM-7, bla OXA-181, bla OXA-232, erm(B), vanA, msr(C), fosA, oqxA, aph(3')-lb, bla PAO, bla OXA-50, catB7, and bla GES-5, in multidrug-resistant bacteria isolated from ICU surfaces in Pakistan and the USA.

The study identified blaNDM genes as the primary cause of carbapenem resistance in Escherichia coli isolates from humans, pigs, chickens, and flies in rural China, highlighting the transmission of these resistance genes between humans and backyard animals.

The study identifies blaKPC-2 as the dominant carbapenemase gene in clinical CRKP isolates, along with various ESBLs and other resistance genes such as blaCTX-M, blaTEM, blaSHV, aac(3)-IId, rmtB, QnrS1, oqxA, oqxB, fosA, catA1, catA2, dfrA1, and dfrA17.

The study describes the first characterization of blaKPC-2 carrying Klebsiella pneumoniae, Escherichia coli, and Enterobacter asburiae isolates in Thailand, highlighting their resistance to carbapenems and other antibiotics.

The study demonstrates the capability of MinION sequencing combined with NanoOK RT software to rapidly identify pathogens and their antimicrobial resistance gene profiles in preterm infants, enabling real-time diagnostics and resistance profiling.

The study demonstrates the capability of MinION sequencing combined with NanoOK RT software to rapidly identify pathogens and their antimicrobial resistance gene profiles in preterm infants, enabling real-time diagnostics and resistance profiling.

The study identifies several AMR genes in multidrug-resistant Gram-negative bacteria isolated from German surface waters, highlighting the presence of clinically relevant resistance mechanisms such as bla CTX-M-1, bla CTX-M-15, mcr-1, and others.

The study identified the mcr-1 gene as a major determinant of colistin resistance in Enterobacteriaceae from retail meat, with the fosA3 gene contributing to fosfomycin resistance in a multidrug-resistant E. coli isolate from China.

The study identifies various AMR genes and mutations in Enterococcus faecium and Enterobacter hormaechei isolates from a liver transplant patient, highlighting their roles in resistance to multiple antibiotics.

The study identified multiple AMR genes in extensively drug-resistant Klebsiella pneumoniae isolates, including beta-lactamases (blaSHV-11, blaTEM-1B, blaVEB-1, blaOXA-10, blaKPC-2, blaOXA-9, blaVIM-27, blaCTX-M-15, blaOXA-1, blaOXA-48), aminoglycoside resistance genes (aadA1, ant(2'')-Ia, aph(6)-Id, arr-2, aadA24, aph(3')-Ia, aph(6)-Id, aac(3)-IIa, aac(6')Ib-cr, aac(6')-Ib, aac(6')-Ib-cr), sulfonamide resistance genes (sul1, sul2), tetracycline resistance genes (tet(A), tet(G)), trimethoprim resistance genes (dfrA1, dfrA14, dfrA23), chloramphenicol resistance genes (cmlA1, catB4), and others.

The study identifies a multidrug-resistant Enterobacter hormaechei strain L51 carrying the bla IMP-26 carbapenemase gene and bla SHV-178 ESBL gene, along with other resistance genes on a conjugative IncHI2/2A plasmid.

The study identifies the antimicrobial-resistant Klebsiella grimontii isolate SS141, which exhibits resistance to ampicillin, amoxicillin, and fosfomycin due to the presence of the bla OXY-6-4 and a variant of fosA genes. Additionally, the isolate shows biofilm-forming capabilities on various plastic surfaces.

The study identified several AMR genes in Gram-negative bacteria isolated from LTCF residents, including bla CTX-M-27, bla CTX-M-14, bla TEM-1B, bla IMP-1, and others, which confer resistance to various antibiotics such as β-lactams, aminoglycosides, and fluoroquinolones.

The study identified fosfomycin resistance mechanisms in E. coli isolates from South Korea, including the presence of the fosA3 gene and mutations in glpT, uhpT, and murA. Fosfomycin resistance was found in 6.7% of isolates, with higher rates in LTCF-onset isolates.

The study identifies several antibiotic resistance genes, including bla CTX-M, fosA3, bla TEM, qnrS, and tet(X), which were enriched in the gut resistome of students exposed to swine farm environments. These genes conferred resistance to various antibiotics such as cephalosporins, fosfomycin, penicillins, fluoroquinolones, and tetracyclines.

The study characterizes an IMP-4-producing Klebsiella pneumoniae ST1873 strain, identifying multiple antimicrobial resistance genes including blaIMP-4, blaSHV-2, blaSHV-11, oqxA, oqxB, aph(6)-Id, strA, catA1, dfrA5, sul2, and fosA.

The study identifies seven resistance genes in the pandrug-resistant K. pneumoniae ST11 strain KP65, including bla KPC-2, bla CTX-M-65, rmtB, fosA, and fosA3, along with chromosomal mutations in mgrB and rpsJ that contribute to colistin and tigecycline resistance.

The study identifies seven resistance genes in the pandrug-resistant K. pneumoniae ST11 strain KP65, including bla KPC-2, bla CTX-M-65, rmtB, fosA, and fosA3, along with chromosomal mutations in mgrB and rpsJ that contribute to colistin and tigecycline resistance.

The study identified various AMR genes in CTX-M-producing E. coli isolates from peri-urban wild animals in Brazil, including bla CTX-M-55, bla CTX-M-2, bla CTX-M-15, bla CTX-M-14, and others, indicating the presence of multidrug-resistant bacteria in wildlife.

The study identifies a multidrug-resistant ST 27 Escherichia coli isolate co-harboring bla(NDM-1), mcr-1, and fosA3, highlighting the emergence of resistance to carbapenems, colistin, and fosfomycin.

The study identified 27 unique antibiotic resistance genes in Ewingella americana, including fosA, which confers resistance to fosfomycin. The strain B6-1 exhibited resistance to several antibiotics, including ampicillin, cefazolin, clindamycin, novobiocin, rifampicin, tetracycline, and vancomycin.

The study identified various AMR genes and mutations in Klebsiella pneumoniae isolates from pregnant women in low-income countries, highlighting the prevalence of multidrug-resistant strains and the role of environmental factors in their carriage.

The study identifies several AMR genes, including blaNDM-5, mcr-1, tetA, mdfA, oqxAB, arr-2, aph(4), aac(3)-IV, and fosA3, which are associated with resistance to various antibiotics. These genes were found in a multidrug-resistant E. coli isolate and were shown to be targeted by the antibiotic adjuvant SLAP-S25, enhancing the efficacy of antibiotics against MDR Gram-negative pathogens.

The study identifies fosA10, a novel plasmid-mediated fosfomycin resistance gene originating from Klebsiella pneumoniae, which was transferred to E. coli via IS10. fosA10 conferred high-level fosfomycin resistance when cloned into E. coli.

The study identified several AMR genes in a culture-negative sample from a patient with severe pneumonia, including bla SHV-12, bla KPC-2, bla TEM-1, bla CTX-M-65, aac(3)-IIa, aadA1, dfrA1, sul1, aph(3')-Ia, catA1, fosA, acrA, and rmtB, which confer resistance to various antibiotics.

The study identified various antimicrobial resistance genes in Klebsiella isolates from preterm infants, highlighting the presence of multidrug resistance mechanisms.

The study identified various antimicrobial resistance genes in Klebsiella isolates from preterm infants, highlighting the presence of multidrug resistance mechanisms.

The study characterizes two carbapenemase-producing plasmids, pT18 and pT211, from Proteus mirabilis, highlighting the role of cointegrate plasmids in the dissemination of antibiotic resistance genes. The plasmids carry various resistance genes, including blaKPC-2, blaCTX-M-65, blaTEM-1B, rmtB, and fosA3, contributing to multidrug resistance.

The study reports the first autochthonous extensively drug-resistant NDM-1 Pseudomonas aeruginosa ST235 strain in Italy, highlighting the presence of multiple beta-lactamase genes, aminoglycoside modifying enzymes, and multidrug efflux pumps contributing to its extensive drug resistance.

The study reports the first autochthonous extensively drug-resistant NDM-1 Pseudomonas aeruginosa ST235 strain in Italy, highlighting the presence of multiple beta-lactamase genes, aminoglycoside modifying enzymes, and multidrug efflux pumps contributing to its extensive drug resistance.

The study identified a multidrug-resistant E. coli strain EC121 harboring 14 antimicrobial resistance genes, including bla CTX-M-2, which confers resistance to multiple beta-lactam antibiotics.

The study presents machine learning models for predicting antimicrobial resistance in Gram-negative bacteria using whole-genome sequencing data. Key resistance genes identified include AAC(6')-Ib, APH(3")-Ib, OqxB21, FosA2, SHV-200, EC-18, CTX-M-222, KPC-33, OXA-51, and OXA-561.

The study identified the fosA gene as a determinant of fosfomycin resistance in carbapenem-resistant Enterobacter cloacae and Klebsiella aerogenes. Five out of eight isolates carried the fosA gene, while none harbored the recently discovered fosL-like gene.

The study identifies IMP-38-producing high-risk ST307 Klebsiella pneumoniae strains in a neonatal unit in China, highlighting the acquisition of diverse antimicrobial resistance genes, including blaIMP-38, blaCTX-M-3, blaSHV-2A, blaSHV-28, blaTEM-1, aacA4, catB3, oqxA, oqxB, and fosA6.

The study identifies fosA3 as a plasmid-mediated fosfomycin resistance gene in ESBL-producing Enterobacterales isolates from retail vegetables in China, highlighting the role of multiple plasmid vectors in its spread.

The study identifies and characterizes the antimicrobial resistance genes and mutations associated with the high-risk Klebsiella pneumoniae clones ST307 and ST147, highlighting their global spread and the diversity of resistance mechanisms they employ.

The study identifies a cluster of extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae sequence type 101 isolated from food and humans, highlighting the potential role of food as a source of multidrug-resistant bacteria transmission to humans.

The study identifies fosA3 as a novel plasmid-mediated fosfomycin resistance gene in E. coli isolates in Spain. Fosfomycin resistance is primarily due to defects in the UhpT transporter system, while nitrofurantoin resistance involves mutations in nfsA, nfsB, and ribE genes.

The study identified fosA3 as a major contributor to fosfomycin resistance in carbapenemase-producing Klebsiella pneumoniae. Additionally, mutations or loss of glpT and/or uhpT were associated with high-level fosfomycin resistance. The silence of fosA3 was observed in some fosfomycin-susceptible isolates.

The study identifies a multidrug-resistant Klebsiella pneumoniae strain carrying several AMR genes, including blaCTX-M-15, blaTEM-1B, blaSHV-27, aac(3)-IId, aadA1, sul2, tetB, tetD, fosA-like, oqxA, oqxB, and qnrE1, highlighting the potential of native Amazonian fish as reservoirs of clinically relevant AMR genes.

The study compared hybrid assembly approaches for bacterial pathogen genomes and identified AMR genes such as blaZ, msr(A), and tet(K) in Staphylococcus aureus.

The study compared hybrid assembly approaches for bacterial pathogen genomes and identified AMR genes such as blaZ, msr(A), and tet(K) in Staphylococcus aureus.

The study identified NDM-5-producing CRKP and SIM-producing hvKP strains, highlighting the emergence of novel resistance mechanisms and the effectiveness of tigecycline-carbapenem combinations in treating these infections.

The study identified three novel Tn7-like transposons (Tn6813, Tn6814, and Tn6765) in Enterobacterales isolates from food-producing animals in China, which carry multiple antibiotic resistance genes including blaDHA-1, qnrA1, aac(6')-Ib-cr, floR, mphE, msrE, and lunF. These transposons contribute to multidrug resistance in the isolates.

The study identified several AMR genes in two hypermucoviscous Klebsiella pneumoniae isolates from renal transplant recipients, including bla CTX-M-15, aac(6')-Ib-cr, and others, indicating resistance to various antibiotics.

The study identifies and characterizes three fosA genes (fosA3, fosA8, and a novel fosA7.5) from fosfomycin-resistant E. coli clinical isolates, demonstrating their role in conferring resistance to fosfomycin.

The study highlights the utility of whole genome sequencing (WGS) in monitoring antimicrobial resistance (AMR) trends, particularly in identifying ESBL genes such as bla CTX-M-1, bla CTX-M-15, bla SHV-12, bla CMY-2, and bla DHA-1, along with other resistance genes like sul2, tet(A), dfrA17, aadA5, ant3-1a, strA, strB, and fosA3 in E. coli isolates from pig surveillance.

The study identified fosA as a key gene responsible for fosfomycin resistance in Klebsiella pneumoniae, and its inactivation significantly reduced resistance.

The study reports the emergence of the mcr-9.1 gene in a colistin-resistant Enterobacter kobei strain isolated from a critically endangered franciscana dolphin in Brazil, along with various other AMR genes.

The study characterizes two clinical Enterobacter cloacae complex isolates co-producing VIM and MCR enzymes, identifying specific AMR genes and their resistance mechanisms.

The study identified multiple antimicrobial resistance genes in bacterial isolates from chronic non-healing wounds, including beta-lactamases, aminoglycoside modifying enzymes, macrolide resistance genes, and others. These genes were found in various bacterial species such as E. coli, S. aureus, P. aeruginosa, and others.

The study identified mcr-1-positive Enterobacterales in retail chicken in Egypt, including Escherichia coli and Citrobacter freundii. It also found the fosA4 gene associated with fosfomycin resistance and various extended-spectrum β-lactamase (ESBL) genes such as bla CTX-M-9, bla CTX-M-14, bla CTX-M-15, and bla SHV-12.

The study identified several AMR genes and mutations in Pseudomonas spp. isolated from chicken meat in Norway, including beta-lactamases, efflux pumps, and genes involved in resistance to aminoglycosides, fluoroquinolones, and colistin.

The study identified several extended-spectrum beta-lactamase (ESBL) genes, including bla CTX-M-15, bla CTX-M-8, bla CTX-M-27, bla CTX-M-14, and bla CTX-M-55, along with mcr-1.1 and mcr-3.1 for colistin resistance. Additionally, various other resistance genes such as qnrS1, mdf(A), mph(A), and others were found in the isolates, indicating multidrug resistance.

The study identified ESBL/AmpC-producing and fosfomycin-resistant E. coli in poultry farms in southern Brazil, highlighting the presence of bla CTX-M group 1, 2, and 8 genes, the cit gene, and the fosA3 gene as key contributors to antimicrobial resistance.

The study identifies multiple AMR genes in endophytic ESBL-producing Enterobacterales isolated from fresh vegetables, highlighting their potential role in the spread of antibiotic resistance.

The study identifies multiple AMR genes and mutations in multidrug-resistant Klebsiella pneumoniae ST101 clone, including blaCTX-M-15, blaOXA-48, blaOXA-1, blaSHV-106, blaTEM-150, aac(3)-IIa, aac(6')-Ib-cr, oqxA10, oqxB17, fosA, catB3, dfrA14, tet(D), and mutations in mgrB, ompK35, gyrA, and parC.

The study identifies fosA3 and bla CTX-M-14 in multidrug-resistant Citrobacter freundii isolates from flowers and retail environments in China, highlighting the role of untypable plasmids in the spread of these resistance genes.

The study identifies a novel hybrid plasmid, pCRHV-C2244, in a carbapenem-resistant Klebsiella pneumoniae ST11 isolate, which encodes the β-lactamase KPC-2 along with various virulence factors. The plasmid shows stable maintenance without significant fitness costs and enhances virulence in vitro and in vivo.

The study presents a DNA microarray-based assay for the simultaneous detection of 44 sepsis-relevant bacterial pathogens, 360 virulence factors, and 409 antibiotic resistance genes. The assay was evaluated with 14 multidrug-resistant strains, including all ESKAPE pathogens.

The study identified multiple clades of IMP-producing Enterobacter cloacae complex sequence type 78 (ST78) strains causing an institutional outbreak. These strains carried blaIMP-1 and blaIMP-11 genes on IncHI2 and IncL/M plasmids, along with various other resistance genes such as aac(6')-IIc, qnrB6, fosA, sul1, and tet(B).

The study identifies bla CTX-M-15 and bla KPC-3 as key resistance genes in Klebsiella pneumoniae isolates from Portuguese hospitals, along with fosA contributing to fosfomycin resistance. Methylation analysis reveals unique patterns around these genes.

The study identifies a carbapenem-resistant Klebsiella pneumoniae isolate carrying the plasmid-mediated AmpC gene blaDHA-1, along with other resistance genes such as blaOXA-1, aac(6')-Ib-cr, aph(3')-Ia, sul1, oqxA, oqxB, qnrB4, arr-3, tet(A), catB3, mph(A), fosA, IncFIB(K), and IncR.

The study identified various AMR genes and mutations in Gram-negative bacteria isolated from chronic wounds in Ghana, including beta-lactamases, fosfomycin resistance genes, chloramphenicol resistance genes, aminoglycoside resistance genes, fluoroquinolone resistance genes, tetracycline resistance genes, sulfonamide resistance genes, trimethoprim resistance genes, and efflux pumps. Mutations in gyrA, parE, and parC were also found to contribute to fluoroquinolone resistance.

The study identifies several antimicrobial resistance genes in a genetically adapted Pseudomonas aeruginosa isolate from a COVID-19 patient, including aph(3')-IIb, blaOXA-395, blaPAO, fosA, and catB7, which confer resistance to aminoglycosides, beta-lactams, fosfomycin, and phenicols.

The study identifies the coproduction of Tet(X7), FosA4, and Mcr-1.1 in E. coli strains from chickens in Egypt, highlighting the emergence of multidrug-resistant bacteria with resistance to tigecycline, fosfomycin, and colistin.

This study identified several antimicrobial resistance genes in Pasteurella multocida, including aminoglycoside, beta-lactam, tetracycline, macrolide, and sulfonamide resistance genes, highlighting the diverse resistance mechanisms present in this pathogen.

The study reports the emergence of a high-level carbapenem-resistant and extensively drug-resistant (XDR) Escherichia coli strain N7 producing NDM-5, highlighting the presence of multiple resistance genes on plasmids and chromosomes.

The study identified fosA3 and fosA5 as the main fosfomycin resistance genes in carbapenem-resistant Klebsiella pneumoniae strains, with fosA3 being the predominant mechanism. These genes were found on transferable plasmids and surrounded by insertion sequence IS26.

The study identified fosA3 and fosA5 as the main fosfomycin resistance genes in carbapenem-resistant Klebsiella pneumoniae strains, with fosA3 being the predominant mechanism. These genes were found on transferable plasmids and surrounded by insertion sequence IS26.

The study identified various AMR genes and mutations in P. aeruginosa isolates from a CF patient, including beta-lactamases, aminoglycoside-modifying enzymes, fluoroquinolone resistance genes, and mutations in regulatory and structural genes contributing to resistance against multiple antibiotics.

The study identified bla CTX-M, bla NDM, mcr-1, and fosA3 as the major AMR genes in ExPEC isolates from healthy chickens in China, highlighting the presence of multidrug-resistant ExPEC, including those carrying mcr-1 and bla NDM.

The study identifies that reduced expression of fosA and the peptidoglycan-recycling pathway genes leads to fosfomycin collateral sensitivity in Pseudomonas aeruginosa antibiotic-resistant mutants.

The study identified fosA3 and bla(CTX-M-14) as key genes responsible for fosfomycin and beta-lactam resistance in E. coli O101:H9-ST10 and O101:H9-ST167 strains isolated from diarrheal calves in a Chinese farm. The fosA3 gene was found to be chromosomally located in some isolates and plasmid-borne in others, while bla(CTX-M-14) was co-localized with fosA3 on plasmids.

The study identified a high prevalence of fosA3-positive E. coli isolates in a pigeon farm in China, highlighting the role of horizontal and clonal transfer in the spread of fosfomycin resistance.

The study identifies several AMR genes and mutations associated with third-generation cephalosporin resistance in Enterobacter cloacae complex, including blaACT-16, blaACT-15, blaACT-7, qnrB1, qnrB19, qnrS2, fosA, oqxA, oqxB, mdfA, and mutations in ampD.

The study reports an outbreak of NDM-1-producing Klebsiella pneumoniae in an ICU during the COVID-19 pandemic, highlighting the presence of multiple AMR genes including blaNDM-1, blaTEM-1, blaCTX-M-15, blaOXA-1, blaCMY-4, and others, along with mutations in ParC and GyrA contributing to quinolone resistance.

The study reports the co-occurrence of fosA5, bla(SHV-145), and bla(OXA-48) in a Klebsiella pneumoniae ST16 isolate from China, highlighting the presence of multiple antimicrobial resistance genes.

The study identified the presence of sul2, aminoglycoside resistance gene aadA, fosfomycin resistance gene fosA, and fluoroquinolone resistance gene gyrB in all three B. trematum isolates. Additionally, isolate two carried a beta-lactamase gene (bla) conferring resistance to ampicillin and ampicillin/sulbactam.

The study identified various AMR genes in K. pneumoniae strains, including beta-lactamases (blaSHV, blaOXA, blaTEM, blaCTX-M), fosfomycin resistance (fosA), quinolone resistance (oqxA, qnrB), chloramphenicol resistance (catB3), aminoglycoside resistance (aac(3), aadA1, strB), sulfonamide resistance (sul1), trimethoprim resistance (dfrA), and tetracycline resistance (tet(A)).

The study identifies bla(VIM-2) and bla(KPC-2) genes in multidrug-resistant Pseudomonas aeruginosa isolates from Colombia, highlighting their diverse genetic environments and mechanisms of resistance.