Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
fosfomycin resistance glutathione transferase FosA8
Overview
Multiple mutations in lipid-A modification pathway & novel fosA variants in colistin-resistant Klebsiella pneumoniae.
The study identifies novel and rare mutations in the arnT and eptA genes involved in lipid A modification pathways, along with novel fosA variants, contributing to colistin resistance in Klebsiella pneumoniae.
Identification of FosA8, a Plasmid-Encoded Fosfomycin Resistance Determinant from Escherichia coli, and Its Origin in Leclercia adecarboxylata.
The study identifies fosA8, a novel plasmid-encoded fosfomycin resistance gene in Escherichia coli, which was originally found in Leclercia adecarboxylata. FosA8 confers high-level fosfomycin resistance through glutathione S-transferase activity.
Identification and Characterization of a Novel FosA7 Member from Fosfomycin-Resistant Escherichia coli Clinical Isolates from Canadian Hospitals.
The study identifies and characterizes three fosA genes (fosA3, fosA8, and a novel fosA7.5) from fosfomycin-resistant E. coli clinical isolates, demonstrating their role in conferring resistance to fosfomycin.
Selective Culture Medium for Screening of Fosfomycin Resistance in Enterobacterales.
The study developed a selective culture medium called SuperFOS for screening fosfomycin-resistant Enterobacterales. It successfully detected fosfomycin resistance in various strains, including those harboring plasmid-mediated resistance genes such as fosA3, fosA4, fosA8, and fosL1.
FosA8-producing E. coli ST131: clinical cases in Italy, February 2023.
The study identified FosA8-producing E. coli ST131 in two patients in Italy, highlighting the emergence of fosfomycin resistance in this high-risk clone.
Genomic Analysis of Cronobacter condimenti s37: Identification of Resistance and Virulence Genes and Comparison with Other Cronobacter and Closely Related Species.
The study identified 17 antimicrobial resistance genes in Cronobacter condimenti s37, including genes involved in resistance to multiple antibiotic classes such as beta-lactams, tetracyclines, macrolides, phenicols, quinolones, aminoglycosides, glycopeptides, peptide antibiotics, rifamycins, nitroimidazoles, phosphonic acid derivatives, diaminopyrimidine derivatives, and elphamycins.
Detection and Whole-Genome Characteristics of Bordetella trematum Isolated from Captive Snakes.
The study identified three AMR genes in Bordetella trematum isolates from captive snakes: tmexD4, adeF, and fosA8, which confer resistance to tetracyclines, fluoroquinolones/tetracyclines, and fosfomycin, respectively.
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