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Explore antimicrobial resistance genes from the literature

ResLit

fosY

bacillithiol transferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to fosY

AMR Rules

Browse AMR rules for fosY

Validation StatusConfirmed2+ DBs

Overview

Mechanism: enzyme-mediated resistance
Validation Method: cloning into pTXΔ and MIC testing
Drug Classes: Fosfomycin, FOSFOMYCIN
Organisms: Staphylococcus aureus
Geographic Location: China|Thailand
Alleles: 2
Papers: 1
Databases: Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Allele Variants2

Allele	Database	Papers	Drug Classes	Organisms	Countries	Years	Sequence Accession	Protein Accession
FosY	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	4	Fosfomycin, FOSFOMYCIN	Staphylococcus aureus	China\|Thailand	2022	MN961674.1\|CP091523\|OM925572

Papers1

The novel fosfomycin resistance gene fosY is present on a genomic island in CC1 methicillin-resistant Staphylococcus aureus.

PMID 35332834 · 2022

The study identifies a novel fosfomycin resistance gene, fosY, located on a genomic island (RI fosY) in CC1 methicillin-resistant Staphylococcus aureus. The gene was experimentally validated to confer fosfomycin resistance through cloning and MIC testing.

Gene Information

Gene Name: fosY
Allele: FosY
Encodes: bacillithiol transferase
Source Database: Reslit
Mechanism: enzyme-mediated resistance
Confers Resistance To: Fosfomycin
Organisms Tested In: • Staphylococcus aureus
Geographic Location: China|Thailand
Validation Method: cloning into pTXΔ and MIC testing
Sequence Accession: MN961674.1|CP091523|OM925572

The novel fosfomycin resistance gene fosY is present on a genomic island in CC1 methicillin-resistant Staphylococcus aureus.

PMID 35332834 · 2022

Gene Information

Gene Name: fosY
Allele: fosY
Source Database: ResFinder Database
Mechanism: Enzymatic inactivation
Confers Resistance To: FOSFOMYCIN
Organisms Tested In: • Staphylococcus aureus
Sequence Accession: MN961674

PMID N/A

Gene Information

Gene Name: fosY
Allele: FosY
Encodes: fosfomycin resistance bacillithiol transferase FosY
Source Database: Reference Gene Catalog
Mechanism: Enzymatic inactivation
Confers Resistance To: FOSFOMYCIN
Organisms Tested In: • Staphylococcus aureus
Sequence Accession: MN961674.1
Protein Accession: QTE33800.1
Notes: ARO:3007069

PMID N/A

Gene Information

Gene Name: fosY
Allele: FosY
Encodes: fosfomycin resistance bacillithiol transferase FosY
Source Database: ResFinder Database
Mechanism: Enzymatic inactivation
Confers Resistance To: FOSFOMYCIN
Organisms Tested In: • Staphylococcus aureus
Sequence Accession: MN961674.1
Protein Accession: QTE33800.1
Notes: ARO:3007069

PMID N/A

Gene Information

Gene Name: fosY
Allele: FosY
Encodes: fosfomycin resistance bacillithiol transferase FosY, fosfomycin thiol transferase
Source Database: Card Database
Mechanism: Enzymatic inactivation, antibiotic inactivation
Confers Resistance To: FOSFOMYCIN
Organisms Tested In: • Staphylococcus aureus
Sequence Accession: MN961674.1
Protein Accession: QTE33800.1
Notes: ARO:3007069