The study identifies and characterizes novel SCCmec-SCCM1 composite islands in MRSA isolates, highlighting the presence of various AMR genes such as blaZ, erm(A), aadD, qacA, qacC, merA, merB, fosB, sdrM, aacA-aphD, far1 (fusB), Q6GD50 (fusC), and cat-pC194 (pMC524).

The study identified various AMR genes in nasal Staphylococcus aureus isolates from donkeys, including blaZ, erm(A), erm(C), tet(M), and fusC, which confer resistance to penicillin, erythromycin, tetracycline, and fusidic acid.

The study identifies a novel 51-kb pseudo SCC mec -SCC-SCC CRISPR composite element in ST779/t878 MRSA isolates, containing mecA, fusC, copB, copC, and novel ccrAB4 and ccrC alleles.

The study identifies a novel staphylococcal cassette chromosomal element, SCCfusC, which carries the fusC gene responsible for fusidic acid resistance and the speG gene contributing to polyamine resistance in methicillin-resistant Staphylococcus aureus (MRSA).

The study identifies fusC as a key gene responsible for fusidic acid resistance in community-associated meticillin-resistant Staphylococcus aureus (CA-MRSA). It also reports the emergence of chimeric SCC mec-fus cassettes that confer dual resistance to β-lactams and fusidic acid.

The study analyzed non-pseudomonal bacterial species from pediatric cystic fibrosis patients, identifying several AMR genes and mutations. Key findings include the presence of beta-lactamase genes (blaZ, blaI, blaRI) in Staphylococcus aureus, fosfomycin resistance gene fosB, fusidic acid resistance gene fusC, and efflux pumps smeZ, smeJ, and smeK in Stenotrophomonas maltophilia. Additionally, Enterobacter cloacae isolates carried resistance genes qacE delta 1, sul1, and dfrA5.

The study identified fusB and fusC genes as the primary mediators of fusidic acid resistance in commensal staphylococci, highlighting their potential role as reservoirs for resistance genes.

The study identified various AMR genes in MRSA isolates from Kuwait hospitals, including aphA3, aacA-aphD, ermA, ermC, mupA, tetK, tetM, fusC, far1, msrA, mphC, sat, qacA, qacC, merA, merB, dfrS1, aadD, fosB, cat, sdrM, icaA, icaC, and icaD, which conferred resistance to multiple antibiotics.

The study characterizes the diversity of SCCmec elements in Staphylococcus aureus isolates from South-Eastern Germany, identifying various SCCmec subtypes and their associated resistance genes, including mecA, mecC, fusC, and other SCC-associated markers.

The study identified multiple antimicrobial resistance genes and mutations in Staphylococcus aureus isolates from meat products, including resistance to β-lactams, macrolides, aminoglycosides, tetracyclines, and others.

The study identifies fusC gene carriage and fusA mutations as the primary mechanisms of fusidic acid resistance in Staphylococcus aureus from Danish atopic dermatitis patients.

The study identified several AMR genes, including mecA, fusB, fusC, blaZ, qacA/qacC, ileS2, and ACME-arc, in nasal staphylococci from medical students, highlighting the potential for gene transfer between S. aureus and CoNS in the absence of antibiotic pressure.

The paper discusses various antimicrobial resistance genes and mutations in staphylococci of animal origin, highlighting their roles in resistance to multiple antibiotics such as macrolides, lincosamides, streptogramins, oxazolidinones, and others. Key genes include erm, msr, mph, ere, lnu, vga, cfr, optrA, dfr, fus, ileS2, blaZ, aadD, ble, fosD, fosB, czrC, and qac genes, which confer resistance to specific antibiotics and are prevalent in different staphylococcal species.

The study identified rpoB mutations and fusB/fusC genes associated with rifampin and fusidic acid resistance in Staphylococcus aureus isolates from tuberculosis patients receiving rifampin-containing regimens.

The paper discusses the mechanisms of antibiotic resistance in Staphylococcus aureus, focusing on beta-lactam resistance through the blaZ and mecA genes, glycopeptide resistance via the vanA operon, and resistance to other antibiotics through various genes and mutations.

The study identified fusA mutations, fusB, and fusC as resistance determinants for fusidic acid in canine-derived staphylococci. Additionally, qacA/B and smr were found to be associated with chlorhexidine resistance.

The study identified several AMR genes in multidrug-resistant staphylococci from high-frequency touched surfaces in London, including blaZ, qacA/B, dfrC, norA, ant(4')-Ib, AAC(6')-Ie-APH(2")-Ia, fusB, msrA, ermC, mphC, tetK, mupA, cat, dfrG, lnuA, fusC, aph3-IIIa, sat4A, vgaA, and others. These genes conferred resistance to various antibiotics such as penicillin, fusidic acid, mupirocin, tetracycline, erythromycin, and chloramphenicol.

The study identifies a novel SCCmec VI element harbouring the fusC gene, which confers fusidic acid resistance in Staphylococcus aureus strains from the Arabian Gulf region.

The study identified LA-MRSA isolates belonging to CC96, CC97, and CC398, with CC97 being the dominant clone. Resistance genes such as erm(A), erm(C), msr(A), aacA-aphD, fusC, tet(K), cat, and dfrS1 were detected, indicating multidrug resistance.

The study identified CC15-MRSA-V+SCCfus isolates carrying genes for resistance to multiple antibiotics, including aacA-aphD, fusC, inu(A), and tet(K).

The study identified high prevalence of multidrug-resistant ST239 isolates with strong biofilm-producing ability. Key AMR genes included mupA, fusC, erm(A), erm(C), ant(4')-Ia, aac(6')-Ie/aph(2''), aph(3')-IIIa, tetM, and tetK.

The study identified various AMR genes in MRSA isolates from Kuwait hospitals, including mupA, aacA-aphD, erm(A), erm(C), tet(K), tet(M), fusC, fusB, and faR1, which conferred resistance to mupirocin, gentamicin, erythromycin, tetracycline, and fusidic acid.

The study identified various methicillin-resistant Staphylococcus aureus (MRSA) strains in the United Arab Emirates, including novel variants with resistance genes such as fusC, ermC, aacA-aphD, mupR, and cfr. These genes confer resistance to fusidic acid, erythromycin/clindamycin, gentamicin, mupirocin, and chloramphenicol/florfenicol/linezolid/tigecycline, respectively.

The study identifies Bucl8 as a component of a novel tetrapartite efflux pump that confers resistance to fusaric acid in Burkholderia pseudomallei and Burkholderia mallei. Expression of the Bucl8-pump in E. coli also conferred FA resistance.

The study identified several AMR genes in ST72 isolates, including blaZ, aadD, ermC, msr(A), mph(C), tetK, aac(6')-aph(2'), fusC, and dfrG, which confer resistance to various antibiotics. K07-204 showed resistance to methicillin, ampicillin, erythromycin, kanamycin, and tetracycline, while K07-561 exhibited resistance to ampicillin and tetracycline. Additionally, K07-204 was found to be highly resistant to lysostaphin.

The study confirms that fusC mediates resistance to fusidic acid and mupA mediates high-level resistance to mupirocin in multiple S. aureus genetic backgrounds. Exposure to sub-inhibitory concentrations of these antibiotics leads to the selection of multidrug-resistant S. aureus strains.

The study identified various AMR genes and mutations in S. aureus isolates from SSTIs in ambulatory patients in Portugal, including blaZ, mecA, erm(A), erm(C), msr(A), mph(C), aadD, aacA-aphD, aph(3')-IIIa, and fusC, along with mutations in grlA, gyrA, and fusA associated with fluoroquinolone and fusidic acid resistance.

The study characterizes the fusC gene, which confers resistance to fusidic acid in Staphylococcus aureus CC1153. The gene is part of a novel SCC mec/fusC chimeric element and shows variation in its surrounding regions.

The study identified several AMR genes in commensal CoNS from healthy individuals in Germany, including mecA, tetK/L, tetM, ermA, ermC, ermB, fusB, fusC, aac(6')/aph(2"), cat194, fexB, and spc. These genes were associated with resistance to methicillin, tetracycline, erythromycin, fusidic acid, gentamicin, chloramphenicol, florfenicol, and spectinomycin.

The study identified three genetic determinants, fusA mutation (fusA), fusB, and fusC, responsible for fusidic acid resistance in methicillin-resistant Staphylococcus aureus isolates from Kuwait hospitals. The majority of isolates carried fusC, while fusA mutations were associated with high-level resistance.

The study developed a lateral flow immunoassay for detecting Panton-Valentine leukocidin (PVL) in Staphylococcus aureus isolates from skin and soft tissue infections. The assay showed 100% sensitivity and specificity. The study also identified the presence of pvl genes and fusC, a fusidic acid resistance gene, in MRSA and MSSA isolates.

The study reports the first isolation of CC5-MRSA-IV-SCCfus 'Maltese Clone' from bat guano in Algeria, highlighting the presence of fusidic acid resistance element fusC, fosfomycin resistance gene fosB, and penicillinase gene blaZ in the MRSA isolates.

The study identified fusB and fusC genes in S. epidermidis and fusB/C in M. sciuri as the primary genetic determinants of fusidic acid resistance. A V599I mutation in the fusA gene was also found in one S. epidermidis isolate, although it did not significantly increase resistance levels.

The study identified several AMR genes in methicillin-resistant staphylococci isolates from goats and their farm environments in Saudi Arabia, including mecA, blaZ, norA, lmrS, mepA, mepR, arlR, arlS, tet(38), mecR1, dfrC, fusC, fosB, fexA, tetM, msrA, mphC, fusB, APH(3′)-IIIa, tetK, and dfrG. These genes confer resistance to various antibiotics such as penicillins, fluoroquinolones, aminoglycosides, macrolides, phenicols, diaminopyrimidines, oxazolidinones, tetracyclines, and fosfomycin.

The study identified multiple AMR genes in the multidrug-resistant S. hominis ShoR14 isolate, including tetK, norA, aac(6')-aph(2"), aadD, blaZ, mecA, mupA, fusC, ermC, sul4, dfrC, and catA7, which contribute to resistance against various antibiotics.

The study benchmarked two bioinformatic workflows for analyzing whole-genome sequenced Staphylococcus aureus isolates, focusing on their ability to predict antibiotic resistance genes and mutations. The 1928 platform and in-house pipeline showed high agreement in predicting resistance genes such as mecA and mecC, as well as mutations in grlA, grlB, and gyrA that confer resistance to ciprofloxacin.

The study identifies a fusidic acid resistance gene (fusc) in a meticillin-resistant Staphylococcus aureus (MRSA) strain causing an outbreak of impetigo in the Netherlands.

The study identified several AMR genes in multidrug-resistant S. aureus strains, including blaZ, mecA, mecC, norA, norC, MgrA, tet(45), APH(3′)-IIIa, ermC, AAC(6′)-APH(2″), and fusC. These genes confer resistance to various antibiotics such as beta-lactams, fluoroquinolones, tetracyclines, aminoglycosides, macrolides, lincosamides, streptogramin B, and fusidic acid.

The study identified various antimicrobial resistance genes in Staphylococcus species isolated from diabetic foot ulcers and healthy skin, highlighting the prevalence of resistance to beta-lactams, aminoglycosides, macrolides, tetracyclines, fusidic acid, trimethoprim-sulfamethoxazole, fosfomycin, kanamycin, neomycin, and quaternary ammonium compounds.

The study identified several antibiotic resistance genes in Staphylococcus aureus isolates from both patients and retail meat, including blaZ, fosB-Saur, tet38, mphC, msrA, sat4, mecA, aph(3')-IIIa, and fusC. These genes were associated with resistance to various antibiotics such as penicillin, tetracycline, macrolides, and fusidic acid.

The study identified specific mutations and gene acquisitions in OM-MRSA ST45 isolates that confer resistance to fluoroquinolones, fusidic acid, gentamicin, and doxycycline, highlighting their increased pathogenicity and resistance mechanisms compared to CL-MRSA ST45 isolates.

The study identified novel methicillin-resistant Staphylococcus pseudintermedius (MRSP) lineages, including ST726 and ST551, and characterized antimicrobial resistance genes such as mecA, blaZ, tetK, and mupA. It also noted a high prevalence of multidrug resistance (MDR) among MRSP isolates.

The study identified novel Staphylococcal cassette chromosome mec (SCC mec ) elements in four methicillin-resistant coagulase-negative Staphylococci (CoNS) isolates from healthy medical students. The isolates harbored various antimicrobial resistance genes, including mecA, blaZ, mphC, msrA, tetK, fusC, fusF, qacA, qacB, qacC, norA, copB, arsC, cadC, cadD, copZ, copA, copR, and czcD, which conferred resistance to beta-lactams, macrolides, tetracyclines, fusidic acid, quaternary ammonium compounds, fluoroquinolones, and heavy metals.

The study identifies a novel variant of a CC15 livestock-associated MRSA strain from Egypt that carries the exfoliative toxin gene etA, highlighting potential increased virulence and the need for enhanced surveillance.

The paper discusses three main mechanisms of fusidic acid resistance in Staphylococcus aureus: mutations in the fusA gene encoding EF-G, expression of resistance proteins like FusB, FusC, FusD, and FusF, and mutations in the rplF gene encoding ribosomal protein uL6. These mechanisms involve either direct interference with FA binding, target protection, or disruption of the FA-locked state of EF-G.

Three Staphylococcus pseudintermedius isolates from dogs and humans in Egypt were characterized. The isolates showed resistance to various antibiotics, including penicillin, tetracycline, aminoglycosides, chloramphenicol, fusidic acid, macrolides, streptothricin, and trimethoprim. None of the isolates carried the mecA gene, which is associated with methicillin resistance.

The study identified several AMR genes in Staphylococcus aureus ST1 isolates from New Zealand, including blaZ, tet(38), mecA, mecR1, qacA, qacB, ermC, fusC, mupA, and others. These genes were associated with resistance to various antibiotics such as penicillin, tetracycline, methicillin, quaternary ammonium compounds, erythromycin, fusidic acid, mupirocin, and fluoroquinolones. The study also highlighted the presence of a novel prophage, φSabovST1, in bovine ST1 isolates, which encoded bovine-adapted leukocidins.