gbuA

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guanidinobutyrase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to gbuA

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: metabolic adaptation
Validation Method: gene expression analysis
Drug Classes: meropenem
Organisms: Pseudomonas aeruginosa
Papers: 1
Databases: Reslit

Papers1

Minimal gene signatures enable high-accuracy prediction of antibiotic resistance in Pseudomonas aeruginosa.

PMID 41038842 · 2025

The study identifies minimal gene signatures for high-accuracy prediction of antibiotic resistance in Pseudomonas aeruginosa, highlighting the role of efflux pumps, metabolic adaptations, and porin alterations in resistance mechanisms.

Gene Information

Gene Name: gbuA
Allele: gbuA
Encodes: guanidinobutyrase
Source Database: Reslit
Mechanism: metabolic adaptation
Confers Resistance To: meropenem
Organisms Tested In: • Pseudomonas aeruginosa
Validation Method: gene expression analysis

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gbuA

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gbuA

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