Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
c-di-AMP phosphodiesterase
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| E327* | - | - | Clostridioides difficile | vancomycin | Reslit | Candidate |
| E297K | - | - | - | oxacillinpenicillinamoxicillin clavulanic acid+1 more | Reslit | Candidate |
| Y475C | - | - | - | oxacillinpenicillinamoxicillin clavulanic acid+1 more | Reslit | Candidate |
| H621Y | - | - | - | oxacillinpenicillinamoxicillin clavulanic acid+1 more | Reslit | Candidate |
| I456V | - | - | Staphylococcus aureus | oxacillin | Reslit | Candidate |
| D561E | - | - | Staphylococcus aureus | oxacillin | Reslit | Candidate |
| E183A | - | - | - | nafcillinoxacillin | Reslit | Candidate |
| F241R | - | - | - | nafcillinoxacillin | Reslit | Candidate |
| N182K | - | cyclic-di-AMP phosphodiesterase GdpP | Staphylococcus aureus | nafcillincephalosporins | Reference Gene CatalogReslit | Confirmed |
| S222F | - | - | Staphylococcus aureus | nafcillin | Reslit | Candidate |
| I52V | - | Staphylococcus aureus | oxacillin | Reslit | Candidate |
Mechanisms and impact of antimicrobial resistance in Clostridioides difficile.
Review
In Vitro Selection of High-Level Beta-Lactam Resistance in Methicillin-Susceptible Staphylococcus aureus.
Research Article
Detected in SA0707 strain
Molecular Characterization of Equine Staphylococcus aureus Isolates Exhibiting Reduced Oxacillin Susceptibility.
Research Article
Mutations in GdpP contribute to reduced oxacillin susceptibility.
Altered PBP4 and GdpP functions synergistically mediate MRSA-like high-level, broad-spectrum β-lactam resistance in Staphylococcus aureus.
Research Article
loss-of-function mutation
Genetic Determinants Enabling Medium-Dependent Adaptation to Nafcillin in Methicillin-Resistant Staphylococcus aureus.
Research Article
A mecA-negative strain of methicillin-resistant Staphylococcus aureus with high-level β-lactam resistance contains mutations in three genes.
Research Article
gdpP
Comparative Genomics of Borderline Oxacillin-Resistant Staphylococcus aureus Detected during a Pseudo-outbreak of Methicillin-Resistant S. aureus in a Neonatal Intensive Care Unit.
Research Article