gdx

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small multidrug resistance (SMR) efflux pump

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to gdx

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Validation StatusCandidate

Overview

Validation Method: cloning and overexpression in E. coli
Drug Classes: Quaternary ammonium compounds
Organisms: Escherichia coli
Papers: 1
Databases: Reslit

Papers1

Riboswitch-Associated Guanidinium-Selective Efflux Pumps Frequently Transmitted on Proteobacterial Plasmids Increase Escherichia coli Biofilm Tolerance to Disinfectants.

Research Article

PMID 32928929 · 2020

The study identified and characterized the GDM member sugE(p) and gdx, which are plasmid-encoded efflux pumps that increase E. coli biofilm tolerance to quaternary ammonium compounds (QACs).

Gene Information

Gene Name: gdx
Allele: gdx
Encodes: small multidrug resistance (SMR) efflux pump
Source Database: Reslit
Confers Resistance To: quaternary ammonium compounds
Organisms Tested In: • Escherichia coli
Validation Method: cloning and overexpression in E. coli
Sequence Accession: YP_002302254.1|NP_418572.4|NP_415075.1

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gdx

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gdx

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