glmR

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protein

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to glmR

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: regulates cephalosporin resistance
Validation Method: deletion and complementation analyses
Drug Classes: cephalosporins
Organisms: Enterococcus faecalis, Enterococcus faecium
Papers: 1
Databases: Reslit

Papers1

Reciprocal regulation of enterococcal cephalosporin resistance by products of the autoregulated yvcJ-glmR-yvcL operon enhances fitness during cephalosporin exposure.

PMID 38512984 · 2024

YvcJ and GlmR reciprocally regulate cephalosporin resistance in Enterococcus faecalis. YvcJ negatively regulates resistance, while GlmR positively regulates resistance. Mutation of YvcJ (K18A) abolishes UDP-GlcNAc binding and removes negative regulation of resistance.

Gene Information

Gene Name: glmR
Allele: glmR
Encodes: protein
Source Database: Reslit
Mechanism: regulates cephalosporin resistance
Confers Resistance To: cephalosporins
Organisms Tested In: • Enterococcus faecalis
• Enterococcus faecium
Validation Method: deletion and complementation analyses
Sequence Accession: NC_017316.1

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glmR

Gene Information

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glmR

Gene Information