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Explore antimicrobial resistance genes from the literature
UDP-N-acetylglucosamine pyrophosphorylase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| glmU | Reslit | 1 | - | Pseudomonas aeruginosa +1 | - | 2008 | - | - |
| GlmU | Reslit | 1 | - |
| - |
| 2024 |
| - |
| - |
Cellular reporter screens for inhibitors of Burkholderia pseudomallei targets in Pseudomonas aeruginosa.
The study developed cellular reporter screens for inhibitors of Burkholderia pseudomallei targets in Pseudomonas aeruginosa, focusing on essential genes such as gyrA, secA, and glmU. These genes were found to be critical for bacterial viability and were used to identify potential inhibitors through bioluminescence reporter assays.
Integration of molecular docking and molecular dynamics simulations with subtractive proteomics approach to identify the novel drug targets and their inhibitors in Streptococcus gallolyticus.
The study identified three potential drug targets in Streptococcus gallolyticus: GlmU, PPAT, and RpoD. Computational methods were used to predict and validate the binding of natural product compounds to these targets, highlighting their potential as novel therapeutics.
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