gloB

hydroxyacylglutathione hydrolase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to gloB

Browse AMR rules for gloB

Overview

Drug Classes: Cefoxitin, Cefotaxime, Cefpodoxime, Ceftriaxone, Cephalexin, Phenicols, Ciprofloxacin, Erythromycin, Levofloxacin, Linezolid, Nitrofurantoin, Penicillin, Tetracycline, Trimethoprim
Papers: 1
Mutations: 3

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
-	C1235T	-	-	cefoxitincefotaximecefpodoxime+11 more	Reslit	Candidate
-	G1234A	-	-	cefoxitincefotaximecefpodoxime+11 more	Reslit	Candidate
-	G1236A	-	-	cefoxitincefotaximecefpodoxime+11 more	Reslit	Candidate

Papers1

1

Evolution of extended-spectrum β-lactamase-producing ST131 Escherichia coli at a single hospital over 15 years.

Research Article

PMID 38168243 · 2023

Mutation Information

gloB: c.C1235T gloB: c.G1234A gloB: c.G1236A

Nucleotide Change: C1235T, G1234A, G1236A
Confers Resistance To: cefoxitincefotaximecefpodoximeceftriaxonecephalexinphenicolsciprofloxacinerythromycinlevofloxacinlinezolidnitrofurantoinpenicillintetracyclinetrimethoprim
Source Database: Reslit